Analysis finds PSA levels predict which men with recurrent prostate cancer will be harmed by adding long-term hormone therapy to radiation
Tag: Clinical Trials
Noninvasive radiation tx offers long-term benefits to pts with high-risk heart arrhythmia
Image-guided cardiac radioablation dramatically reduces episodes of fast, abnormal heartbeats for more than 2 years
PACIFIC survival explained: Cancer spread reduced, new distant growth most often in the brain
Vast majority of new, distant lesions from metastatic non-small cell lung cancer (NSCLC) occurred in a single site or very few sites, pointing to a potential role for further local therapy
Trial finds high-dose radiation effective for men whose prostate cancer has spread
Phase II, randomized trial data show targeted radiation sparks immune system response similar to vaccination
New genes identified in hearing loss, providing treatment hope
A new study published today in The American Journal of Human Genetics has identified 44 genes linked to age-related hearing loss giving a much clearer understanding of how the condition develops and potential treatments. In the study, researchers from King’s…
Adding radiation after immunotherapy improves PFS for some pts with metastatic NSCLC
Treating a single tumor with high-dose radiation boosts the immune system and shrinks distant tumors for some patients
Blood-brain barrier damage occurs even with mild head trauma — Ben-Gurion U study
BEER-SHEVA, ISRAEL…September 25, 2019 – In a new study of adolescent and adult athletes, researchers at Ben-Gurion University of the Negev, Stanford University and Trinity College in Dublin have found evidence of damage to the brain’s protective barrier, without a…
Study assesses asthma treatment options in African American children and adults
Use of long-acting bronchodilators had no impact for some African American children
HSS researchers identify factor essential for tendon growth
Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research by investigators at Hospital for Special Surgery (HSS). The findings provide a strong rationale for pursuing clinical…
Baby brain scans made available online to advance research
The Developing Human Connectome Project (dHCP) has published ground-breaking MR brain scans of over 500 newborn babies, which researchers from all over the world can download and use to study how the human brain develops. A collaboration between King’s College…
Children exposed to secondhand smoke at higher risk for atrial fibrillation
Study highlights relationship between parental smoking status and offspring AFib risk
How to Successfully Recruit Minority Adolescents for STI/HIV Prevention Research
Disparities in rates of sexually transmitted infections (STIs) and HIV between Black/African American and Hispanic/Latino adolescents and their white counterparts are well documented. Culturally and developmentally appropriate efforts targeted to help these youth establish healthy practices to lower their risk of sexually transmitted infections are warranted. However, such interventions present unique challenges in recruiting and retaining research participants.
Cross clade immune responses found in South Africa from the RV144/Thai HIV vaccine regimen
SEATTLE, SEPTEMBER 18, 2019 – The results of the study called HVTN 097, titled “Immune correlates of the Thai RV144 vaccine regimen in South Africa” and led by Dr. Glenda Gray, Co-Principal Investigator of the HIV Vaccine Trials Network (HVTN),…
Dana-Farber receives $5 million gift to create the Edward P. Evans Center for MDS
Largest single philanthropic commitment to MDS research and care in Dana-Farber history
Imaging reveals new results from landmark stem cell trial for stroke
Researchers led by Sean I. Savitz, MD, reported today in the journal Stem Cells that bone marrow cells used to treat ischemic stroke in an expanded Phase I trial were not only safe and feasible, but also resulted in enhanced…
Pre-salvage RT PSA predictive of hormone therapy benefit with salvage RT for recurrent prostate cancer
Pre-salvage RT PSA is predictive of hormone therapy benefit with salvage RT for men with recurrent prostate cancer on NRG oncology trial
New SU2C teams accelerate clinical trials for difficult breast & prostate cancers
LOS ANGELES – Stand Up To Cancer (SU2C) is launching teams of experts to lead innovative attacks on two types of cancer that have defied conventional treatment: triple-negative breast cancer (TNBC) in women and metastatic prostate cancer in men. The…
Penn’s Angela DeMichele, MD, MSCE, part of team awarded Stand Up 2 Cancer grant
$3 million award will support combination therapy trial for triple-negative breast cancer
Few people with peanut allergy tolerate peanut after stopping oral immunotherapy
Continuing with a modest dose confers more protection, NIH-funded study finds
Innovative treatment to prevent common brain infection could save NHS £7 million per year
An innovative solution used to prevent common brain infections in patients having surgery for hydrocephalus has been found to significantly reduce infection rates according to a report published in The Lancet today (12 September 2019). Hydrocephalus is a build-up of…
Shimmer announces launch of healthcare industry open source initiative for wearable sensor algorithm
Initiative will enable the development of industry standards for wearable sensor data
Exercising at home has a positive effect on Parkinson’s patients
Even though exercise is known to be healthy, many people find it difficult to maintain an exercise program for a longer time. This applies even more to people with a chronic illness such as Parkinson’s disease, where physical and mental…
Parents to learn signs of sepsis
Sepsis takes the life of more than one million children every year, but thanks to a boost in researc
Breaking the ‘stalemate’ in the most common soft tissue sarcoma in children
First randomized clinical trial to show positive results in rhabdomyosarcoma since 1974
A smart artificial hand for amputees merges user and robotic control
EPFL scientists are developing new approaches for improved control of robotic hands – in particular for amputees – that combines individual finger control and automation for improved grasping and manipulation. This interdisciplinary proof-of-concept between neuroengineering and robotics was successfully tested…
Microbial profile to support growing field of human gut research
George Washington University researchers publish comprehensive list of the types and ratios of micro
A liquid biopsy test can identify patients who may respond to immune checkpoint blockade
Bottom Line: A new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it could help determine which patients are likely to respond to immune checkpoint inhibitors. Journal in Which the Study was Published:…
KEYNOTE-024 three-year survival update
Pembrolizumab effective as first-line therapy for advanced non-small-cell lung cancer
Nurse led follow-up service aids patients with respected early stage lung cancer, improves clinic ef
Barcelona– The presence of the specialist nurse within thoracic surgical centers in the United Kingdom increased clinic capacity and efficiency, reduced waiting time for appointments, promoted junior medical training and ensured continuity of care for the patients, according to an…
Trial seeks to reduce neuropathy, improve outcomes for black women with breast cancer
Researchers at Indiana University School of Medicine have launched a new, unique study recruiting black women with breast cancer designed to better understand and treat neuropathy, a side effect from chemotherapy. The National Cancer Institute-sponsored clinical trial, EAZ171, is led…
Kazan Federal University and Mayo Clinic implement unique spinal rehab technology
Spinal cord stimulation device was implanted to a patient for a first time in Russia at Far Eastern
Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial
Methotrexate was more effective than mycophenolate mofetil at treating severe forms of the eye disea
Third baby born after uterus transplant at Baylor University Medical Center in Dallas
Baylor Scott & White Research Institute program continues to help women with absolute uterine factor
BioMILD trial demonstrates lung cancer screening using MicroRNA blood test enhances prevention
Barcelona–Lung cancer screening efforts have accelerated in the last decade, with researchers showing that low dose CT screening is effective in reducing lung cancer mortality. Now, researchers in Milan report that using a blood test, accompanied by low dose CT…
Feeling legs again improves amputees’ health
Neurofeedback for leg prostheses
Harms and benefits of estrogen therapy among women with a hysterectomy appear to depend on age when
Embargoed news from Annals of Internal Medicine
Feeling legs again improves ampu-tees’ health
Neurofeedback for leg prostheses
Device to detect pre-cancerous Barrett’s Esophagus receives FDA 510(k) clearance
Minimally invasive, cost-effective alternative to endoscopy identifies precursor to cancer of the es
Scientists confirm efficacy of a combination therapy for advanced liver cancer
A procedure that cuts off blood supply to tumors improves the effectiveness of a drug for advanced-s
New study confirms protective effect of diabetes drugs against kidney failure
A new meta-analysis published in The Lancet Diabetes and Endocrinology today has found that SGLT2 inhibitors can reduce the risk of dialysis, transplantation, or death due to kidney disease in people with type 2 diabetes. Lead author Dr Brendon Neuen…
New peanut allergy treatment shows effectiveness and safety
UNC School of Medicine researchers show that tiny under-the-tongue doses of peanut protein can offer
Vast majority of dementia patients don’t receive specialty diagnosis and care, study finds
Researchers found the use of dementia specialty care is particularly low for Hispanics and Asians
LSU Health New Orleans awarded $13.6 million for expanded cancer clinical trials network
New Orleans, LA – LSU Health New Orleans has been awarded a $13.6 million grant by the National Cancer Institute to expand its successful statewide clinical trials network with a special emphasis on minority and underserved cancer patients. Principal Investigator…
A tech intervention to tame tuberculosis
An interactive program using mobile phones helps more patients conclude treatment successfully
National study seeks earlier diagnosis of ATTR cardiac amyloidosis in minorities
Boston Medical Center and Columbia University Irving Medical Center awarded grant for new trial
Human flourishing in an age of gene editing
International uproar followed the recent birth of the first babies created from embryos whose genomes had been edited with a breakthrough technology. Another scientist has announced the intention to create more gene-edited babies. The potential uses of gene-editing technologies such…
Finding an effective way to reduce pressure ulcers
Expensive high-tech air mattresses are only marginally better at preventing pressure sores and ulcers than a specialist foam mattress, according to the results of a major study. Known as an alternating-pressure mattress, the high-tech devices contain air pockets that inflate…
Early life environment may lead to high blood pressure in children
High outdoor temperatures, low city walkability and BPA exposure associated with higher risk of hype
Poor diet causes blindness in a young ‘fussy eater’
Embargoed News from Annals of Internal Medicine
New radiomics model uses immunohistochemistry to predict thyroid nodules
Machine learning models can be trained to extract immunohistochemical (IHC) characteristics from the