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UrduBATON ROUGE, LOUISIANA – In patients with type 2 diabetes, big swings in blood sugar levels between doctors’ visits are associated with an increased risk of heart disease. The study, published in the journal Diabetes, Obesity & Metabolism, looked at…
Tag: METABOLISM/METABOLIC DISEASES
New clues to how muscle wasting occurs in people with cancer
UNIVERSITY PARK, Pa. — Muscle wasting, or the loss of muscle tissue, is a common problem for people with cancer, but the precise mechanisms have long eluded doctors and scientists. Now, a new study led by Penn State researchers gives…
Insulin can be stored out of refrigeration in hot settings!
A team from UNIGE and MSF has shown that a vial of insulin can be stored for 4 weeks after opening and at up to 37°C, without losing efficacy
Harvard researchers use machine learning models to study health impacts of walnuts
Findings show eating walnuts leaves a metabolomic signature in the body linked with lower risk of type 2 diabetes and cardiovascular disease.
Biomedical basis of the Barker hypothesis uncovered
According to the Barker hypothesis (Hales and Barker 1992) (also referred to as “small baby syndrome”), infants with too low body weight have an increased risk of suffering from cardiovascular diseases, high blood pressure, diabetes and chronic kidney diseases in…
Body and mind: hormones in the brain may explain how exercise improves metabolism
During moderate exercise, the brain’s hypothalamus – the region controlling metabolism – releases a hormone linked to obesity resistance, according to research in mice.
New policy guidance highlights urgent global need for post-fracture care programs
‘Capture the Fracture® (CTF) Partnership – Guidance for Policy Shaping’ sets out a step-by-step approach to building secondary fracture prevention policy which can improve patient outcomes, save healthcare costs, and save lives
New research looks at teen bariatric surgery outcomes by age
Results of study, published in Pediatrics, support early intervention based on clinical indication rather than age alone
New IOF position paper urges routine use of DXA-VFA in fracture liaison services
Vertebral fractures often remain undetected, despite their significance as risk factors for future fractures; routine use of VFA in fracture liaison services would help physicians detect unrecognized fractures and inform treatment decisions
Social media study reveals diabetics’ fear of disrupted insulin supplies because of Brexit
Diabetics living in the UK worry about disruption to insulin supplies as a result of Brexit, new research shows.
Scientists discover a new promising target for diabetes treatment
Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum Muenchen, the Technical University of Munich and the German Center for Diabetes Research is a significant milestone for diabetes research as the…
New benchmark set to deliver optimal osteoporosis care throughout Asia Pacific
Launch of first pan-Asia Pacific minimum clinical standards for the screening, diagnosis & management of osteoporosis
New York Tech researchers secure NIH grant, study decalcification as heart disease therapy
A New York Institute of Technology research team led by Olga V. Savinova, Ph.D., assistant professor of biomedical sciences at New York Institute of Technology College of Osteopathic Medicine (NYITCOM), has secured a five-year grant from the National Institutes of…
A compound that slows bone loss, and a resource for developing treatments to slow aging
Longitudinal and functional study of 700 aging mice provides a treasure trove of data for those studying aging and age-related diseases
The longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation
Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight . Reduced expression of mINDY, which is…
Study helps understand why kids of obese mothers may be susceptible to metabolic diseases
The phenomenon may be associated with a deficiency of the protein mitofusin-2 in the mother’s eggs, which affects the shape and functioning of mitochondria.
Mouse study identifies novel compound that may help develop diabetes drugs
COLUMBUS, Ohio – Research led by The Ohio State University Wexner Medical Center and College of Medicine identified a new compound that might serve as a basis for developing a new class of drugs for diabetes. Study findings are published…
The interconnection of global pandemics — Obesity, impaired metabolic health and COVID-19
In a Nature Reviews Endocrinology article authors from the German Center for Diabetes Research (DZD) highlight the interconnection of obesity and impaired metabolic health with the severity of COVID-19. First, they provide information about the independent relationships of obesity, disproportionate…
Diabetes powerfully associated with premature coronary heart disease in women
A new biomarker of insulin resistance was tied to a 600 percent increase in risk of premature coronary heart disease
Eating habits partly down to your genetics, finds new study
Your food intake patterns are partly under genetic control, according to the latest research from researchers at King’s College London, published today in the journal Twin Research and Human Genetics . Researchers can study the quality of an individual’s typical…
Lack of physical exercise during COVID-19 confinement may lead to a rise in mortality
In a review article published in Frontiers of Endocrinology, Brazilian researchers estimate a reduction of 35% in levels of physical activity and a rise of 28% in sedentary behavior in the initial months of confinement imposed by the pandemic
New research finds connection: Inflammation, metabolism and scleroderma scarring
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.
NIH study compares low-fat, plant-based diet to low-carb, animal-based diet
People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of…
General health checkups may detect early signs of Parkinson’s disease
A research team led by Nagoya University in Japan has found that blood pressure, the hematocrit (the percentage of red blood cells in blood), and serum cholesterol levels change in patients with Parkinson’s disease long before the onset of motor…
Green med diet cuts non-alcoholic fatty liver disease by half – Ben-Gurion U. study
BEER-SHEVA, Israel…January 18, 2021 – A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver disease (NAFLD) in half, according to a long-term clinical intervention trial led by Ben-Gurion University of the…
IOF and IFCC review calls for harmonization of assays for reference bone turnover markers
New review describes the current status of assays for PINP and β-CTX in blood, as well as the plans for and progress towards the achievement of harmonization or standardization of commercial assays for these reference markers
Physical frailty syndrome: a cacophony of multisystem dysfunction
In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related pathophysiology underpinning the clinical…
How plants produce defensive toxins without harming themselves
Defense and autotoxicity: Researchers elucidate the biosynthesis and mode of action of diterpene glycosides in wild tobacco
Ovarian cancer cells adapt to their surroundings to aid tumor growth
New study brings us closer to targeted treatments that suppress the growth of ovarian cancer, which is often fatal, as early stages are hard to detect
Scientists modeled protein behavior of archaeal viruses to crack protein folding mystery
Scientists from the Pacific Quantum Center of Far Eastern Federal University (FEFU) figured out how the AFV3-109 protein with slipknot structure folds and unfolds depending on temperature. The protein is typical for the viruses of the oldest single-celled organisms that…
Scientists reveal mechanism that causes irritable bowel syndrome
KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study,…
HEALTHCARE NUTRITION COUNCIL LEADS THE WAY ON MEDICAL FOOD DISCUSSIONS
Announcement of Publication of Workshop Proceedings
Tissue stiffness likely drives immune responses in many chronic diseases
Buck research points to the possibility of new immunotherapeutics and highlights critically needed changes in experimental techniques
Hip fracture incidence expected to increase two-to-three fold in some Eurasian countries
A new report on the burden of osteoporosis in the Russian Federation and seven other Eurasian countries warns of increasing fracture rates due to expected demographic changes, and poor access to diagnosis and treatment.
New taxonomy of non-skeletal rare disorders with impact on bone
Outlines six groups of rare disorders that may influence the activity of bone cells or the characteristics of bone matrix, classified according to the systemic disease, genetic defect, pathophysiology of bone phenotype, and therapy.
High doses of saccharin don’t lead to diabetes in healthy adults, study finds
A new study led by researchers at The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine found the sugar substitute saccharin doesn’t lead to the development of diabetes in healthy adults.
Prevalence of patients receiving dialysis in China may exceed 800,000 by 2025
Study published in the American Journal of Kidney Diseases (AJKD) projects that prevalence of patients receiving dialysis in China will increase from 384.4 patients per million (PPM) in 2017 to 629.7 PMP in 2025 with a predicted 874,373 patients receiving…
Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation
Promises new approaches to treat diseases
How the circadian clock regulates liver genes in time and space
Nothing in biology is static. Biological processes fluctuate over time, and if we are to put together an accurate picture of cells, tissues, organs etc., we have to take into account their temporal patterns. In fact, this effort has given…
Landmark study reveals link between gut microbes, diet and illnesses
Diets rich in healthy and plant-based foods encourages the presence of gut microbes that are linked to a lower risk of common illnesses including heart disease, research has found. A large-scale international study using metagenomics and blood chemical profiling has…
Study reveals strong links between gut microbes, diet and metabolic health
A large-scale international study uses metagenomics and blood analysis to uncover gut microbes associated with the risks for common illnesses such as diabetes and heart disease.
Prediabetes subtypes identified
All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases. This is…
New USC study on circadian clock shows “junk DNA” plays a key role in regulating rhythms
Study suggests the impact of non-coding microRNAs on circadian rhythms is tissue specific and may reveal new insights into disease processes
Study of 50,000 people finds brown fat may protect against numerous chronic diseases
Brown fat is that magical tissue that you would want more of. Unlike white fat, which stores calories, brown fat burns energy and scientists hope it may hold the key to new obesity treatments. But it has long been unclear…
ASN applauds release of 2020 Dietary Guidelines
Integral Role of ASN and ASN Members in DGA Development Exemplifies ASN’s Leadership in the Field of Nutrition Science
UOC to study whether intermittent fasting slows down ageing in postmenopausal women
Faculty of Health Sciences researchers Salvador Macip and Marta Massip are leading a three-year research project funded by the Ministry of Science and Innovation
Polysaccharides from red algae affect mice immune systems, say FEFU scientists
Carrageenans, biologically active polysaccharides isolated from red algae and widely used in the food industry as stabilizers, thickeners, or jelly agents have an express effect on the immune systems of mice, a study reports. The research was carried out by…
Quick look under the skin
Self-learning algorithms analyze medical imaging data
New drug combination could improve glucose and weight control in diabetes
Adding an experimental cancer drug to a widely used diabetes medicine enhances glucose management and weight control in mice
Light flips genetic switch in bacteria inside transparent worms
Light-controlled genes could reveal how gut bacteria impact health