Regulatory T cells (Tregs)* prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective. Researchers at Helmholtz Zentrum München and LMU Munich have now deciphered a mechanism that impairs…
Tag: METABOLISM/METABOLIC DISEASES
Form of severe malnutrition linked to DNA modification
A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level – the chemical tags in DNA that help regulate gene expression – between two clinically distinct forms of acute childhood malnutrition known…
Type 1 Diabetes: New starting point to delay autoimmune response
Regulatory T cells (Tregs)* prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective. Researchers at Helmholtz Zentrum München and LMU Munich have now deciphered a mechanism that impairs…
Your DNA is not your destiny — or a good predictor of your health
New study from the University of Alberta suggests that diseases such as many cancers, diabetes, and Alzheimer’s have a genetic contribution of 5 to 10 per cent at most
Caffeine may offset some health risks of diets high in fat, sugar
CHAMPAIGN, Ill. — A new study in rats suggests that caffeine may offset some of the negative effects of an obesogenic diet by reducing the storage of lipids in fat cells and limiting weight gain and the production of triglycerides.…
Two-year Ellipsys data featured at annual Controversies in Dialysis Access (CiDA) Meeting
Innovative endoAVF technology is a ‘true paradigm shift’ in dialysis access, leading physicians say
Eating too much — not exercising too little — may be at core of weight gain, study finds
Findings about children’s calorie expenditure challenge conventional wisdom and may provide clues for reversing global trends in obesity, Baylor University researcher says
Two-year Ellipsys data featured at annual Controversies in Dialysis Access (CiDA) Meeting
Innovative endoAVF technology is a ‘true paradigm shift’ in dialysis access, leading physicians say
Eating too much — not exercising too little — may be at core of weight gain, study finds
Findings about children’s calorie expenditure challenge conventional wisdom and may provide clues for reversing global trends in obesity, Baylor University researcher says
Good aerobic fitness doesn’t protect children against type 2 diabetes, staying active does
Good aerobic fitness does not protect children against obesity-induced insulin resistance, which is a key risk factor of type 2 diabetes, a new study from Finland shows. However, more physical activity and less sedentary time were associated with reduced insulin…
In mice, a high-fat, high-sugar diet remodels the microbiome and endocannabinoid system
Washington, DC – December 17, 2019 – Weight gain and diet have long been known to shuffle the population of gut microbes. More recently, studies have also connected weight gain and diet to changes in the intestinal endocannabinoid system (eCB),…
Blood lipid profile predicts risk of type 2 diabetes better than obesity
Using lipidomics, a technique that measures the composition of blood lipids at a molecular level, and machine learning, researchers at Lund University in Sweden have identified a blood lipid profile that improves the possibility to assess, several years in advance,…
Good aerobic fitness doesn’t protect children against type 2 diabetes, staying active does
Good aerobic fitness does not protect children against obesity-induced insulin resistance, which is a key risk factor of type 2 diabetes, a new study from Finland shows. However, more physical activity and less sedentary time were associated with reduced insulin…
In mice, a high-fat, high-sugar diet remodels the microbiome and endocannabinoid system
Washington, DC – December 17, 2019 – Weight gain and diet have long been known to shuffle the population of gut microbes. More recently, studies have also connected weight gain and diet to changes in the intestinal endocannabinoid system (eCB),…
Blood lipid profile predicts risk of type 2 diabetes better than obesity
Using lipidomics, a technique that measures the composition of blood lipids at a molecular level, and machine learning, researchers at Lund University in Sweden have identified a blood lipid profile that improves the possibility to assess, several years in advance,…
Can good sleep patterns offset genetic susceptibility to heart disease and stroke?
For the first time researchers have assessed the impact on the risk of heart or blood vessel problems from the combination of sleep patterns and genetic susceptibility to cardiovascular disease. The study, which is published in the European Heart Journal…
NICE recommends Vifor Pharma’s Veltassa® (patiromer)
A positive final appraisal determination (FAD) for Veltassa® (patiromer) recommends patients in England have access to a new treatment option for treating hyperkalaemia (raised serum potassium levels) in adults 1 Hyperkalaemia is a serious condition, which has a negative impact…
Consumption of chili pepper cuts down the risk of death from a heart or cerebral attack
An Italian study, conducted on twenty-three thousand people and published in the Journal of the American College of Cardiology, shows that regular consumption of this spice is linked to a reduction of death risk for cardiac and cerebrovascular causes
New review study shows that egg-industry-funded research downplays danger of cholesterol
Researchers explain how faulty, industry-funded studies can harm public health
NICE recommends Vifor Pharma’s Veltassa® (patiromer)
A positive final appraisal determination (FAD) for Veltassa® (patiromer) recommends patients in England have access to a new treatment option for treating hyperkalaemia (raised serum potassium levels) in adults 1 Hyperkalaemia is a serious condition, which has a negative impact…
Consumption of chili pepper cuts down the risk of death from a heart or cerebral attack
An Italian study, conducted on twenty-three thousand people and published in the Journal of the American College of Cardiology, shows that regular consumption of this spice is linked to a reduction of death risk for cardiac and cerebrovascular causes
New review study shows that egg-industry-funded research downplays danger of cholesterol
Researchers explain how faulty, industry-funded studies can harm public health
Low income and work stress contribute to link between education, heart disease and stroke
First nationwide study of 1.68 million people
The Lancet: More than one in three low- and middle-income countries face both extremes of malnutrition
Twin presence of obesity and undernutrition reflects shifts in food systems
More than 1 in 3 low- and middle-income countries face both extremes of malnutrition
Being undernourished or overweight are no longer separate public health issues
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
UMass Amherst scientist expanding chemical exposure research to include humans
Mitochondria are the ‘canary in the coal mine’ for cellular stress
Finding by Salk researchers helps explain how some cancers resist chemotherapy
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
UMass Amherst scientist expanding chemical exposure research to include humans
Mitochondria are the ‘canary in the coal mine’ for cellular stress
Finding by Salk researchers helps explain how some cancers resist chemotherapy
New research aims to improve oral delivery of insulin
DETROIT – Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin — a hormone that regulates blood sugar– or the body cannot effectively use the insulin it produces. According to the Diabetes Research Institute…
JDRF awards 23 training grants to advance type 1 diabetes research
Nonprofit funding to accelerate laboratory and clinical research to treat, prevent and drive cures for type 1 diabetes
New research aims to improve oral delivery of insulin
DETROIT – Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin — a hormone that regulates blood sugar– or the body cannot effectively use the insulin it produces. According to the Diabetes Research Institute…
‘Football as Medicine’
Prescribing football for global health promotion
JDRF awards 23 training grants to advance type 1 diabetes research
Nonprofit funding to accelerate laboratory and clinical research to treat, prevent and drive cures for type 1 diabetes
‘Football as Medicine’
Prescribing football for global health promotion
Diet, not exercise, may be key to addressing our biggest cause of liver disease
Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch. Fatty liver disease affects…
$2.5 million to protect the brain from metabolic insult
More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general…
Teams of microbes are at work in our bodies. Here’s how to figure out what they’re doing
Drexel researchers’ algorithm toolkit can identify microbe communities and their functions
Exercise yields some cardiovascular benefits in children with excess weight
Eight months of daily, afterschool physical activity in previously inactive 8- to 11-year-olds with obesity and overweight improved key measures of their cardiovascular health like good cholesterol levels, aerobic fitness and percent body fat, but didn’t improve others like arterial…
Increasing food intake by swapping mitochondrial genomes
Many of the characteristics that make people so different from each other, are often the result of small differences in the DNA between individuals. Variation in just a single base in our DNA can cause significant variation in traits like…
Exercise yields some cardiovascular benefits in children with excess weight
Eight months of daily, afterschool physical activity in previously inactive 8- to 11-year-olds with obesity and overweight improved key measures of their cardiovascular health like good cholesterol levels, aerobic fitness and percent body fat, but didn’t improve others like arterial…
Secret behind diabetes drug’s benefits revealed
Metformin shows benefits on aging and a number of diverse diseases
Increasing food intake by swapping mitochondrial genomes
Many of the characteristics that make people so different from each other, are often the result of small differences in the DNA between individuals. Variation in just a single base in our DNA can cause significant variation in traits like…
Secret behind diabetes drug’s benefits revealed
Metformin shows benefits on aging and a number of diverse diseases
The next step in organ transplants: New startup takes aim at reperfusion injury
Charleston, SC-based Lydex Pharmaceuticals has received a small business technology transfer grant from the NIH to investigate and develop compounds targeting key enzymes responsible for organ damage, inflammation and rejection after transplant
Pilot study finds time-restricted eating has benefits for people at risk for diabetes
Previous studies have looked at employing time-restricted eating (TRE), a form of intermittent fasting, as a way to lose weight and improve health measures such as blood sugar and blood pressure in mice and healthy people. But in a study…
Pilot study finds time-restricted eating has benefits for people at risk for diabetes
Previous studies have looked at employing time-restricted eating (TRE), a form of intermittent fasting, as a way to lose weight and improve health measures such as blood sugar and blood pressure in mice and healthy people. But in a study…
Eating in sync with biological clock could replace problematic diabetes treatment
An early-morning, carb-filled meal improves glycemic control among diabetics, Tel Aviv University researchers say
Eating in sync with biological clock could replace problematic diabetes treatment
An early-morning, carb-filled meal improves glycemic control among diabetics, Tel Aviv University researchers say
The Intersection of Innovation and Practice Heads to Atlanta
Interventional cardiology’s premier event will head to Atlanta, Georgia for annual conference