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UrduLeptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.
Tag: Leptin
New Potential Therapy for Fatty Liver Disease
In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.
Researchers ID Weight and Energy Balance Pathway Independent of Hunger Hormone
Article title: LRP1 regulates food intake and energy balance in GABAergic neurons independently of leptin action Authors: Min-Chel Kang, Ji A. Seo, Hyon Lee, Aykut Uner, Won-Mo Yang, Kellen Cristina Cruz Rodrigues, Hyun Jeong Kim, Wenjing Li, John Nelson Campbell,…
Exercise Makes Female Rats Hungrier, Leads to Weight Gain
Article title: Compensatory eating behaviors in male and female rats in response to exercise training Authors: Rebecca M. Foright, Ginger C. Johnson, Darcy Kahn, Catherine A. Charleston, David M. Presby, Courtney A. Bouchet, Elizabeth A. Wellberg, Vanessa D. Sherk, Matthew…
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Exploring How a Key Blood Pressure Hormone Works in Males and Females
Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body. Researchers at the “Metabolic and sex differences in aldosterone responses” symposium will explore the growing body of research that finds sex is a major determinant of how aldosterone acts on the body.
Researchers Discover New, Treatable Pathway Known to Cause Hypertension in Obese People
There’s no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules — a signaling channel that’s found in a tiny organ on the side of your neck — effectively lowers blood pressure in obese mice, the researchers reported recently in the journal Circulation Research.