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UrduSkaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.
Tag: Cancer
LGBTQI+ Latinx people don’t receive culturally competent cancer prevention and treatment
This ‘double minority’ group reports they are afraid to tell health care providers their gender identity and/or sexual orientation, City of Hope researcher says
Scientists develop new methodology to genetically modify lab mice and human cells
Technique designed by Cedars-Sinai-led team produces personalized models of complex cancers
Neurons promote growth of brain tumor cells
Joint press release by Heidelberg University Hospital and the German Cancer Research Center In a current paper published in the journal ” Nature “, Heidelberg-based researchers and physicians describe how neurons in the brain establish contact with aggressive glioblastomas and…
Key similarities discovered between human and archaea chromosomes
Discovery from Indiana University could advance use of single-celled organism in research on cancers related to errors in cellular gene expression
Study estimates more than 100,000 cancer cases could stem from contaminants in tap water
WASHINGTON – A toxic cocktail of chemical pollutants in U.S. drinking water could result in more than 100,000 cancer cases, according to a peer-reviewed study from Environmental Working Group – the first study to conduct a cumulative assessment of cancer…
Association for Molecular Pathology announces 2019 award recipients
ROCKVILLE, Md. – September 19, 2019 – The Association for Molecular Pathology (AMP), the premier global, molecular diagnostics professional society, today announced the recipients of this year’s Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious…
Psoriasis drug target offers potential for osteosarcoma
A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings from the Garvan Institute of Medical Research suggest. In an animal model, researchers demonstrated that the immune molecule IL23 is central…
New factor in the development of childhood lymphoma
A study recently published in the renowned journal Blood , led by Kaan Boztug, Scientific Director of the St. Anna Children’s Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Adjunct Principal Investigator at the CeMM…
The path of breast-to-brain cancer metastasis
In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers. One of the biggest problems with any type of cancer is metastasis; and when breast cancer metastasizes, the brain…
Yale Cancer Center research highlighted at ASTRO 2019
Yale Cancer Center (YCC) scientists presented research at the 61st annual American Society for Radiation Oncology (ASTRO) annual meeting in Chicago.
Yale Cancer Center research highlighted at ASTRO 2019
Yale Cancer Center (YCC) scientists presented research at the 61st annual American Society for Radiation Oncology (ASTRO) annual meeting in Chicago.
Yale Cancer Center researchers show adding radiation after immunotherapy improves survival time for patients with advanced lung cancer
The results of a phase II clinical trial by Yale Cancer Center (YCC) researchers show adding high-dose radiation after immunotherapy stops working increases survival time for patients with metastatic non-small-cell lung cancer (NSCLC).
Yale Cancer Center researchers show adding radiation after immunotherapy improves survival time for patients with advanced lung cancer
The results of a phase II clinical trial by Yale Cancer Center (YCC) researchers show adding high-dose radiation after immunotherapy stops working increases survival time for patients with metastatic non-small-cell lung cancer (NSCLC).
Novel approach to ultrasound raises possibility of new medical applications
A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. Researchers hope to fine-tune the technique for use in assessing osteoporosis risk and treatment. Researchers have also demonstrated that a variation of the same technique…
Breast cancer screening found effective in men at high risk for the disease
Men at high risk of developing breast cancer may benefit from mammography, or breast X-ray, screening for the disease, a new study shows. The study, publishing in the journal Radiology online Sept. 17, involved 1,869 men, ages 18 to 96,…
Screening mammography could benefit men at high risk of breast cancer
OAK BROOK, Ill. – Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a landmark study published in the journal Radiology . Breast cancer in…
Cancer cells turn to cannibalism to survive chemotherapy, study suggests
Researchers from the Tulane University School of Medicine have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study, which will be published September 17 in the Journal of Cell Biology , suggests that this…
Novel anti-cancer nanomedicine for efficient chemotherapy
Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University,Finland and Huazhong University of Science and Technology,China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use…
Stevens researchers to develop handheld device to diagnose skin cancer
The proven technology will be designed into a handheld device that could reduce need for painful biopsies by 50 percent — and disrupt the $5.3 billion diagnostics market
Targeted radiotherapy technique could cut treatment time from two months to two weeks
Advanced radiotherapy technology could safely deliver curative treatment for some prostate cancer patients in just one or two weeks, according to new research published today.
Synthetic cells capture and reveal hidden messages of the immune system
When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body’s response to various…
‘Death Star’ bacterial structures that inject proteins can be tapped to deliver drugs
Not all bacteria spread diseases, many are beneficial and this strain has nanoscale syringes that deliver proteins which cause metamorphosis in marine animals, and could be modified as a novel drug delivery tool for future vaccines and cancer care
Dana-Farber receives $5 million gift to create the Edward P. Evans Center for MDS
Largest single philanthropic commitment to MDS research and care in Dana-Farber history
Physicians report high refusal rates for the HPV vaccine and need for improvement
The HPV vaccine is one of only two vaccines that prevent cancer but is underutilized in the US
Pre-salvage RT PSA predictive of hormone therapy benefit with salvage RT for recurrent prostate cancer
Pre-salvage RT PSA is predictive of hormone therapy benefit with salvage RT for men with recurrent prostate cancer on NRG oncology trial
New SU2C teams accelerate clinical trials for difficult breast & prostate cancers
LOS ANGELES – Stand Up To Cancer (SU2C) is launching teams of experts to lead innovative attacks on two types of cancer that have defied conventional treatment: triple-negative breast cancer (TNBC) in women and metastatic prostate cancer in men. The…
Renegade genes caught red handed
Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A University of Arizona researcher disputes that belief and hopes to change the paradigm even further.
Penn’s Angela DeMichele, MD, MSCE, part of team awarded Stand Up 2 Cancer grant
$3 million award will support combination therapy trial for triple-negative breast cancer
Two studies show promise, safety of proton therapy in the brain in children with cancer
Penn, CHOP research expands evidence of proton benefit
Patients diagnosed with cancer after skipping appointment more likely to die within a year
Cancer patients who miss an urgent referral appointment for their symptoms are 12% more likely to di
Italian Chemical Society and Elsevier recognize three early-career researchers
The 2019 Reaxys SCI Early Career Researcher Award aims to promote young talent in the chemistry fiel
Search tightens for genes driving prostate cancer
The National Cancer Institute (NCI) is set up to fund individual projects in fields like genomics, computational biology, and pathology. Now researchers at University of Colorado Cancer Center are taking advantage of an innovative new program in cancer systems biology…
Scientists discover new breakthrough in cancer hair loss treatment
Scientists have determined a new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss as a result of cancer treatments. Researchers based at The University of Manchester have discovered a new strategy for how…
Knotty problem of cell reprogramming solved, USC scientists report
The researchers found a way to repurpose cells more reliably than current methods by untangling DNA,
How breast cancer uses exosomes to metastasize to the brain
Study details how exosomes, released by the breast tumor, tricks cells in the blood-brain barrier in
Breaking the ‘stalemate’ in the most common soft tissue sarcoma in children
First randomized clinical trial to show positive results in rhabdomyosarcoma since 1974
Machine learning improves the diagnosis of patients with head and neck cancers
Researchers from Charité – Universitätsmedizin Berlin and the German Cancer Consortium (DKTK) have successfully solved a longstanding problem in the diagnosis of head and neck cancers. Working alongside colleagues from Technische Universität (TU) Berlin, the researchers used artificial intelligence to…
Shimmer announces launch of healthcare industry open source initiative for wearable sensor algorithm
Initiative will enable the development of industry standards for wearable sensor data
Some cancer drugs in clinical trials don’t work by hitting their targets
Multiple cancer drug candidates in clinical trials kill tumor cells through off-target effects instead of by interacting with their intended molecular targets, according to a new study. The unexpected findings demonstrate that the targets of these drugs are not essential…
Gene mutation, tissue location, signaling networks drive cancer incidence and severity
BOSTON – The KRAS gene is one of the commonly mutated genes in cancer. More than 40 percent of colorectal cancers have a mutated KRAS gene, or oncogene, that is at least partially responsible for cancer development. Mutated KRAS genes…
Cancer drugs don’t always work as intended, researchers warn
Scientists at Cold Spring Harbor Laboratory (CSHL) have identified 10 cancer drugs currently in clinical trials that do not work how clinicians thought they would. In identifying what went wrong, experts can now work to improve drug discovery and personalized…
UK improves cancer survival, but is still behind other high-income countries
Cancer survival in the UK has improved since 1995, although it still lags behind other high-income countries, according to new analysis* by the International Cancer Benchmarking Partnership (ICBP), which is managed by Cancer Research UK. The study, published in Lancet…
A liquid biopsy test can identify patients who may respond to immune checkpoint blockade
Bottom Line: A new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it could help determine which patients are likely to respond to immune checkpoint inhibitors. Journal in Which the Study was Published:…
KEYNOTE-024 three-year survival update
Pembrolizumab effective as first-line therapy for advanced non-small-cell lung cancer
Nurse led follow-up service aids patients with respected early stage lung cancer, improves clinic ef
Barcelona– The presence of the specialist nurse within thoracic surgical centers in the United Kingdom increased clinic capacity and efficiency, reduced waiting time for appointments, promoted junior medical training and ensured continuity of care for the patients, according to an…
Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy
Five-year outcomes from the randomized, phase 3 trials checkmate 017/057: nivolumab vs. docetaxel in
Trial seeks to reduce neuropathy, improve outcomes for black women with breast cancer
Researchers at Indiana University School of Medicine have launched a new, unique study recruiting black women with breast cancer designed to better understand and treat neuropathy, a side effect from chemotherapy. The National Cancer Institute-sponsored clinical trial, EAZ171, is led…
NUS invention makes biopsies less invasive and more informative
STAMP technology is a million times more sensitive and comprehensive to accurately detect and classi
New blood test for prostate cancer is highly-accurate and avoids invasive biopsies
A new and simple blood test has been found to efficiently and accurately detect the presence of aggressive prostate cancer, according to research by Queen Mary University of London. In combination with the current prostate specific antigen (PSA) test, the…