The popular heartburn drug ranitidine, commonly known as Zantac, was voluntarily recalled due to the contamination of a human carcinogen that could potentially cause cancer. The recall includes oral tablets, capsules, and syrup.
Tag: Cancer
Inadequacies in current early-stage lung cancer treatment revealed
Researchers from Tohoku University and Tohoku University Hospital have revealed why some existing cancer treatments are ineffective in tackling the early-stages of lung cancer. A team led by Professor Tetsuya Kodama investigated the ability of anti-cancer agents to affect early-stage…
What protects killer immune cells from harming themselves?
White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists from UCL and the Peter MacCallum Cancer Centre in…
Cancer research that’s out-of-this-world
Australia’s first space research mission to the International Space Station will attempt to establish how some of the most aggressive cancer cells behave in a zero-gravity environment
Biennial mammography screening yields more advanced-stage cancers
CHICAGO – Cancers found in patients undergoing annual mammography screening are smaller and less advanced than those found in patients undergoing screenings every two years, according to a new study presented next week at the annual meeting of the Radiological…
A novel pathway to target colorectal cancer
Investigators at the Medical University of South Carolina report in Gastroenterology that PGE2, a signaling molecule involved in inflammation, promotes colorectal cancer progression
UK and China research team take first steps towards a vaccine for pancreatic cancer
Researchers from Queen Mary University of London and Zhengzhou University have developed a personalised vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in…
Biennial mammography screening yields more advanced-stage cancers
CHICAGO – Cancers found in patients undergoing annual mammography screening are smaller and less advanced than those found in patients undergoing screenings every two years, according to a new study presented next week at the annual meeting of the Radiological…
Splicing factor to blame in triple negative breast cancer
A splicing factor called TRA2B enhances triple negative breast cancers’ ability to grow and metastasize.
Linking wound healing and cancer risk
When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down…
A novel pathway to target colorectal cancer
Investigators at the Medical University of South Carolina report in Gastroenterology that PGE2, a signaling molecule involved in inflammation, promotes colorectal cancer progression
UK and China research team take first steps towards a vaccine for pancreatic cancer
Researchers from Queen Mary University of London and Zhengzhou University have developed a personalised vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in…
Splicing factor to blame in triple negative breast cancer
A splicing factor called TRA2B enhances triple negative breast cancers’ ability to grow and metastasize.
Linking wound healing and cancer risk
When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down…
Research: Alcohol and tobacco policies can reduce cancer deaths
Policies aimed at cutting alcohol and tobacco consumption, including the introduction of random breath testing programs and bans on cigarette advertising, have resulted in a significant reduction in Australian cancer death rates, new research shows. The La Trobe Centre for…
Intestinal Stem Cell Genes May Link Dietary Fat and Colon Cancer
Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a Rutgers study. The study, published in the journal Gastroenterology, describes a new connection between the way cells consume fat and how genes regulate stem cell behavior in the intestines of mice.
NF decline but stable QOL in 1st year after temozolomide-based chemoradiotherapy
NRG oncology trial shows neurocognitive function decline but stable quality of life in first year after temozolomide-based chemoradiotherapy for patients with high risk, low-grade gliomas
Encouraging normal liver cells to fight cancer
A study conducted at the VIB-KU Leuven Center for Cancer Biology discovered that healthy liver tissue surrounding a tumor activates a defence mechanism that restrains tumor growth. Remarkably, the researchers found that hyperactivation of this mechanism above levels normally present…
Study reveals lower rates of cancer and early death in Adventists, including among black individuals
A recent study found lower rates of premature death and cancer in Seventh-day Adventists, a Protestant denomination long known for health promotion, compared with individuals in the general U.S. population. Published early online in CANCER , a peer-reviewed journal of…
Breakthrough in understanding common childhood cancer
Scientists studying one of the most common forms of childhood cancer have made an important breakthrough in understanding how the disease progresses. Neuroblastoma is a rare type of cancer of the nervous system that mainly affects babies and young children.…
Safety evaluation of conditionally immortalized cells for renal replacement therapy
Here, the research team assessed the safety of conditionally immortalized proximal tubule epithelial cells for bioartificial kidney application, by using in vitro assays and athymic nude rats
Anchored by a dense neighborhood: What stops cells from going astray
Researchers from the Mechanobiology Institute (MBI) at the National University of Singapore have shown that cells can attach to the fibrous protein meshwork that surrounds them only if the fibres are spaced close enough. The team’s findings, which can explain…
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target
The cover for issue 61 of Oncotarget features Figure 4, ‘The influence of stress conditions on API-5 expression and inhibition,’ by Bousquet, et al.
Recovering from metabolic syndrome significantly reduces risk for cardiovascular disease
Embargoed News from Annals of Internal Medicine
Prostate cancer: radiation therapy effective in patients with no further treatment options
Reports of new cancer treatments often raise high hopes and expectations, particularly, of course, among cancer patients and their families. But raising expectations is not something that Samer Ezziddin, Professor of Nuclear Medicine and Director of the Department of Nuclear…
Using gene scissors to detect diseases
The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors – which scientists can use to edit genetic material – in order to better diagnose…
Konstanz-based CRC 969 to receive additional funding
The Konstanz-based research in the area of cellular proteostasis will receive funding in the amount of approximately EUR ten million for another four years, at the end of which it will have reached its maximum funding period of twelve years.…
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
Encouraging normal liver cells to fight cancer
A study conducted at the VIB-KU Leuven Center for Cancer Biology discovered that healthy liver tissue surrounding a tumor activates a defence mechanism that restrains tumor growth. Remarkably, the researchers found that hyperactivation of this mechanism above levels normally present…
Cellular origins of pediatric brain tumors identified
Researchers make a breakthrough by identifying that several aggressive pediatric brain tumors are the result of stalled development in embryonic cells
Study reveals lower rates of cancer and early death in Adventists, including among black individuals
A recent study found lower rates of premature death and cancer in Seventh-day Adventists, a Protestant denomination long known for health promotion, compared with individuals in the general U.S. population. Published early online in CANCER , a peer-reviewed journal of…
NF decline but stable QOL in 1st year after temozolomide-based chemoradiotherapy
NRG oncology trial shows neurocognitive function decline but stable quality of life in first year after temozolomide-based chemoradiotherapy for patients with high risk, low-grade gliomas
Safety evaluation of conditionally immortalized cells for renal replacement therapy
Here, the research team assessed the safety of conditionally immortalized proximal tubule epithelial cells for bioartificial kidney application, by using in vitro assays and athymic nude rats
Prostate cancer: radiation therapy effective in patients with no further treatment options
Reports of new cancer treatments often raise high hopes and expectations, particularly, of course, among cancer patients and their families. But raising expectations is not something that Samer Ezziddin, Professor of Nuclear Medicine and Director of the Department of Nuclear…
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target
The cover for issue 61 of Oncotarget features Figure 4, ‘The influence of stress conditions on API-5 expression and inhibition,’ by Bousquet, et al.
Using gene scissors to detect diseases
The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors – which scientists can use to edit genetic material – in order to better diagnose…
Recovering from metabolic syndrome significantly reduces risk for cardiovascular disease
Embargoed News from Annals of Internal Medicine
Konstanz-based CRC 969 to receive additional funding
The Konstanz-based research in the area of cellular proteostasis will receive funding in the amount of approximately EUR ten million for another four years, at the end of which it will have reached its maximum funding period of twelve years.…
Cellular origins of pediatric brain tumors identified
Researchers make a breakthrough by identifying that several aggressive pediatric brain tumors are the result of stalled development in embryonic cells
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
Cancer patients are at higher risk of dying from heart disease and stroke
More than one in ten cancer patients do not die from their cancer but from heart and blood vessel problems instead, according to new research published in the European Heart Journal [1] today (Monday). For some cancers, like breast, prostate,…
‘Magic bullet’ takes aim at pancreatic cancer
Every day, more than 1200 people worldwide are told they have pancreatic cancer. Within 12 months, 80 per cent of them will have succumbed to the disease. It’s one of the most lethal cancers in the world but new research…
Using Artificial Intelligence to determine whether immunotherapy is working
Researchers use AI with routine CT scans to predict how well lung cancer patients will respond to expensive treatment based off changes in texture patterns inside and outside the tumor.
Tiny devices made of DNA detect cancer with fewer false alarms
DNA circuits could help ensure that cancer screens and therapies zero in on the right culprits
Biosimilar for HER2+ breast cancer: Overall response rate matches reference trastuzumab
ESMO Asia Congress 2019
Combination of immunotherapy and VEGF inhibitor improves survival in HCC
ESMO Asia Congress 2019
Breast cancer recurrence after lumpectomy & RT is treatable with localized RT without mastectomy
NRG Oncology trial shows that breast cancer recurrence after lumpectomy and radiation is treatable with localized radiation without mastectomy
Ohio State-developed drug receives FDA approval for treatment of CLL and SML
COLUMBUS, Ohio – On Nov. 21, 2019, the U.S. Food and Drug Administration (FDA) approved the use of the drug acalabrutinib for first-line therapy in chronic lymphocytic leukemia (CLL) and small cell lymphoma (SCL). This is the first full approval…
In a first for cell biology, scientists observe ribosome assembly in real time
The imaging feat clarifies how RNA molecules fold — and might one day translate into better medicines for a host of diseases
Department of Defense awards grant to Stephenson researcher for lung cancer study
OKLAHOMA CITY – Cancer researchers operate from a fundamental premise: Tumor cells are very smart. Because of their ability to disguise themselves, hide or otherwise evade the immune cells that can kill them, the key to successful treatment depends upon…