New funding from NIH will help Lehigh University computer science and engineering professor Brian Chen develop software that can identify relevant protein mutations and explain their significance
Month: December 2019
Majority of children with allergies needlessly avoid common antibiotics
Eight in 10 children who reported being allergic to common classes of antibiotics used to treat respiratory, skin and intestinal infections were not truly allergic to it, a new study shows. The research, led by the Murdoch Children’s Research Institute…
Old drug offers new hope for children with devastating disorder
Fenfluramine reduces seizures, is safe for patients with dravet, study shows
Meerkat mobs do ‘war dance’ to protect territory
Meerkat clans perform a ‘war dance’ to frighten opponents and protect their territory, according to a new UCL and University of Cambridge study. Published in Proceedings of the Royal Society B , this is the first empirical study to reveal…
The Lancet: Drug could help reduce frequency of seizures for children with Dravet Syndrome, a severe treatment-resistant epilepsy, compared with placebo
14-week randomised controlled trial of 119 children aged between 2-18 years finds evidence for the benefit of fenfluramine in Dravet syndrome when given in addition to existing anti-epilepsy drugs
Martin, Pappu, Yang among most highly-cited researchers worldwide
Washington University ranks seventh in the world for its number of highly-cited researchers
Caring for a grandchild linked to lower risk of loneliness and social isolation
Active grandparents have larger social networks than those without this role
Significant safety issues for kids on long term ventilation at home
In nearly half of officially reported incidents in England and Wales over 5 years, child came to harm, analysis shows
Vaping may have similar effects to smoking on harmful lung bacteria
E-cigarette vapor may have similar effects to cigarette smoke on bacteria associated with smoking-related illness such as chronic obstructive pulmonary disease (COPD) and asthma, according to a study published in Respiratory Research . Although e-cigarettes are perceived as a safer…
Dogs process numerical quantities in similar brain region as humans, study finds
Unique experiment explores canine ‘numerosity’
Can good sleep patterns offset genetic susceptibility to heart disease and stroke?
For the first time researchers have assessed the impact on the risk of heart or blood vessel problems from the combination of sleep patterns and genetic susceptibility to cardiovascular disease. The study, which is published in the European Heart Journal…
New tool reveals DNA structures that influence disease
UNIVERSITY PARK, Pa. — Disruption of certain DNA structures — called topologically associating domains, or TADs — is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps elucidate the complex…
Air quality tests need simplifying to help reduce dangerous emissions
New methods of testing and simulating air quality should be considered in order to help policy makers have a more accurate understanding of how emissions affect air pollution levels, new research suggests. In a review published in the Journal of…
Stand out from the herd: How cows commoonicate through their lives
First evidence of cows maintaining individual vocalization | Study explains why farmers should take note
Mothers’ and babies’ brains ‘more in tune’ when mother is happy
Mothers’ and babies’ brains can work together as a ‘mega-network’ by synchronising brain waves when they interact. The level of connectivity of the brain waves varies according to the mum’s emotional state: when mothers express more positive emotions their brain…
Novel genetic signature that can predict some kinds of breast cancer is identified
The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, as a model of angiogenesis, with analysis of transcriptomic gene expression profiles from public breast cancer databases.
Plant-eating insects disrupt ecosystems and contribute to climate change
A new study from Lund University in Sweden shows that plant-eating insects affect forest ecosystems considerably more than previously thought. Among other things, the insects are a factor in the leaching of nutrients from soil and increased emissions of carbon…
Protein injections in medicine
One day, medical compounds could be introduced into cells with the help of bacterial toxins
Mass General team detects Alzheimer’s early using electronic health records
BOSTON – A team of scientists from Massachusetts General Hospital (MGH) has developed a software-based method of scanning electronic health records (EHRs) to estimate the risk that a healthy person will receive a dementia diagnosis in the future. Their algorithm…
A closer look at the diabetes disaster
In a new book, Amy Moran-Thomas examines how diabetes is reaching epidemic levels in countries across the world.
Screen could offer better safety tests for new chemicals
CAMBRIDGE, MA — It’s estimated that there are approximately 80,000 industrial chemicals currently in use, in products such as clothing, cleaning solutions, carpets, and furniture. For the vast majority of these chemicals, scientists have little or no information about their…
Disruption of glycine receptors to study embryonic development and brain function
Collaborative work identified a new function for glycine receptors during embryonic development
How vulnerable is your car to cyberattacks?
Even the smartest of smart cars have issues
Legionella Conference 2020 moves to Chicago with a health care focus
NSF Health Sciences and National Environmental Health Association partner for public health conference
Blood lipid profile predicts risk of type 2 diabetes better than obesity
Using lipidomics, a technique that measures the composition of blood lipids at a molecular level, and machine learning, researchers at Lund University in Sweden have identified a blood lipid profile that improves the possibility to assess, several years in advance,…
Clinical trial results in critical care medicine to be unveiled at leading UK conference
Results of three major critical care trials, and a fourth major international epidemiological sepsis study, to be unveiled at an international conference in Northern Ireland
Researchers create functional mini-liver by 3D bioprinting
Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future
Moffitt researchers develop more efficient approach to create mouse models
Chimera mouse models and chimera-derived melanoma cell lines provide a faster approach to study skin cancer
100,000s of people select names for exoplanet systems
On 17 December 2019 the names of 112 sets of exoplanets and host stars named in the IAU100 NameExoWorlds campaigns were announced at a press conference in Paris (France). Within the framework of the International Astronomical Union’s 100th anniversary commemorations…
Multiple sclerosis: New standards required for planning clinical trials
The patient perspective needs more consideration
Gastric cancer susceptibility marker discovered
Gastric cancer, the third most common cause of cancer-related deaths, is often associated with a poor prognosis because it tends to be diagnosed at an advanced stage and is therefore difficult to treat. To reduce the death rate, it is…
Changes in the immune system explain why belly fat is bad for thinking
Iowa State researchers have found for the first time that less muscle and more body fat may affect how flexible our thinking gets as we become older, and changes in parts of the immune system could be responsible. These findings…
Changes in opioid-related drug overdose deaths in US
Bottom Line: Researchers analyzed changes in the proportion of drug overdose deaths involving opioids that were certified as suicide, unintentional or of undetermined intent in this observational study. Using 2000-2017 mortality data, researchers report 47,506 total opioid deaths (excluding homicides)…
Possible strategy for cancer treatment found in nuclear transport proteins
Although less often the focus of cancer research, recent studies have hinted at the possible importance of a type of protein known as nuclear transport receptors. Now researchers at Kanazawa University and collaborating institutions in Japan and the US have…
A new playbook for interference
NIST scientists correlate photon pairs of different colors generated in separate buildings
Solving the challenges of long duration space flight with 3D printing
Astronauts on future missions to the Moon and Mars need to be able to make their own spare parts, tools and materials essentially on demand
NASA’s SDO sees new kind of magnetic explosion on sun
NASA’s Solar Dynamics Observatory has observed a magnetic explosion the likes of which have never been seen before. In the scorching upper reaches of the Sun’s atmosphere, a prominence — a large loop of material launched by an eruption on…
AI improves breast cancer risk prediction
OAK BROOK, Ill. – A sophisticated type of artificial intelligence (AI) can outperform existing models at predicting which women are at future risk of breast cancer, according to a study published in the journal Radiology . Most existing breast cancer…
Genomic insights: How female butterflies alter investment in attractiveness vs. fecundity
By analyzing the genomes of orange and white females of the clouded yellow butterfly, researchers have identified the location and key components of an alternative life history switch that is only expressed in females
New animal model shows effective treatment for latent tuberculosis
Top clinicians call the results ‘dramatic’
HIIT timing matters for increasing fitness
60-second intervals with 60-second breaks are effective whereas 30-second ones and 120-second rests aren’t
Blue mushroom dye used to develop new fluorescent tool for cell biologists
A new fluorescent tool for detecting reactive oxygen species based on a chemical found in mushrooms has been developed by scientists at the University of Bath. Reactive oxygen species (ROS), such as free radicals and peroxides, are produced in cells…
How immune cells switch to attack mode
Study led by the University of Bonn reveals how macrophages react immediately after contact with bacteria
In some children with autism, ‘social’ and ‘visual’ neural circuits don’t quite connect
Researchers combined eye gaze data with brain scans to discover that in a common subtype of autism, in which ASD toddlers prefer images of geometric shapes over those of children playing, brain areas responsible for vision and attention are not controlled
Archaeologists find Bronze Age tombs lined with gold
The family tombs are near the 2015 site of the ‘Griffin Warrior,’ a military leader buried with armor, weapons and jewelry.
RIT and IAR observe pulsars for the first time from South America
Upgraded radio telescopes enable scientists to study pulsars from the southern hemisphere
Regenstrief VP co-authors National Academy report on AI’s potential to improve health
Seminal report focuses on hope, hype, promise, and peril of AI use in medical arena
Applying physics principle yields grim prediction on hurricane destruction in an era
BROOKLYN, New York, Tuesday, December 17, 2019 – Global warming could lead to hurricanes even more powerful than meteorologists currently forecast. That warning came from a physicist researching the behavior of tropical cyclones who noticed that one of the principles…
Suboptimal diet and cardiometabolic disease healthcare costs in the US
Approximately $50 billion dollars of the annual healthcare cost of cardiometabolic disease in the US population could be associated with poor diet, according to a research article published this week in the open access journal PLOS Medicine . The results…
Social determinants of health are linked to gun homicide rates
Gun homicide rates in the US are associated with several social determinants of health, including income inequality, government welfare spending, trust in institutions, and social mobility, according to a new study published December 17 in the open-access journal PLOS Medicine…