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UrduMechanical engineering assistant professor Elliot Hawkes is one of 20 Packard Fellows for 2020
Tag: UROGENITAL SYSTEM
A simple, cost-effective molecular assay may help manage growing spread of drug-resistant gonorrhea
A multiplex assay based on high-resolution melting technology accurately identified antimicrobial resistant determinants in Neisseria gonorrhoeae, researchers report in the Journal of Molecular Diagnostics
Inhibitor of KRAS gene mutation shows promise in lung, bowel and other solid tumors
Latest results from KRYSTAL-1 early clinical trial of adagrasib (MRTX849)
Researchers identify genetic variants linked to toxic side effects from bevacizumab
In the largest study of its kind, researchers have found two common genetic variants that can be used to predict whether or not cancer patients might suffer severe adverse side-effects from the drug bevacizumab. The study is unique because researchers…
Study discovers gene that helps us know when it’s time to urinate
Results suggest ‘sixth sense’ PIEZO2 gene may help body sense a full urinary bladder
Body MRI reinterpretations plagued by discrepancies and errors
Secondary interpretations of body MR images at tertiary care centers identify high rate of discrepancies, with cognitive error types predominating, suggesting subspecialty interpretations and additional resources are needed
$1.6 Million grant to reverse urinary incontinence
Electrical stimulation of pelvic floor nerves may re-establish strength
Health care-associated infections among critically ill children
What The Study Did: This observational study looked at changes from 2013 to 2018 in the rates of catheter-associated bloodstream and urinary tract infections among critically ill infants and children the United States. Authors: Heather E. Hsu, M.D., M.P.H., of…
Study could be first step in providing personalized care to patients with ureteral stents
LONDON, ONTARIO – For patients with kidney stones, ureteral stents (hollow devices placed in the ureter – the tube between the kidney and bladder) can be used temporarily to relieve urinary obstruction. Despite the use of antibiotics, ureteral stents often…
Diabetes dramatically reduces the kidney’s ability clean itself
AUGUSTA, Ga. (September 22, 2020) – The kidneys often become bulky and dysfunctional in diabetes, and now scientists have found that one path to this damage dramatically reduces the kidney’s ability to clean up after itself. The natural cleanup is…
Childhood sexual abuse: Mental and physical after-effects closely linked
A new Canadian study reveals that the psychological and physical effects of childhood sexual abuse are closely tied. The finding could help healthcare professionals develop more effective interventions and ultimately improve mental and physical health outcomes for survivors of abuse…
European survey shows alarmingly low awareness of erectile dysfunction
Majority does not know what it is
Cancer drug can rebalance kidney function in a devastating genetic disease
Researchers at the University of Cambridge and the University of Zurich have discovered that a drug newly approved for cancer improves kidney dysfunction in a mouse model of Dent disease 2 and Lowe syndrome The study is published today in…
Prophylactic antivirals prevent chronic HCV in patients receiving kidneys from positive donors
Embargoed News from Annals of Internal Medicine
A new model to predict survival in colorectal cancer
This article by Dr. Mohanad Mohammed and colleagues is published in Current Bioinformatics, 2020
NAMS releases the 2020 Genitourinary Syndrome of Menopause Position Statement
New recommendations for treating women with genitourinary syndrome of menopause reflect the latest proven safe and effective therapeutic options
SGLT2 inhibitors can slow progression of chronic kidney disease
Two randomized controlled studies [1, 2] show: SGLT2 inhibitors can slow CKD progression in all patients, not only in patients with diabetes
Dartmouth awarded NIH grant for device to detect cancer left behind during surgery
Dartmouth engineers have been awarded a $2.5 million grant from the National Cancer Institute ( NCI ), part of the National Institutes of Health ( NIH ), to develop and test a device–a microendoscopic electrical impedance sensing probe– that could…
Reproducing the pathophysiology of polycystic kidney disease from human iPS cells
Understanding the pathogenesis of hereditary polycystic kidney disease and developing new treatments
Urine sediment test results, diagnoses vary significantly across nephrologists
Standardized approaches necessary to increase validity, reliability of widely-used diagnostic test
Genetic cause of congenital malformation discovered
Study by the University of Bonn reveals that genetic information controls development of the urinary tract, rectum and genitals
Penis microbiota predicts if a man’s female partner will develop bacterial vaginosis
Bacterial Vaginosis (BV) is an infection affecting more than 20% of women worldwide.
Penis microbiota predicts if a man’s female partner will develop bacterial vaginosis
Bacterial vaginosis is triggered by BV-related bacteria present in some men’s penile microbiome
Drug used to slow kidney disease found to be ineffective
Following a major clinical trial, clinicians find the drug allopurinol does not prevent worsening of kidney disease. The Australasian Kidney Trials Network led a large, two-year study, known as CKD-FIX, to assess the effectiveness of allopurinol, in slowing the rate…
Drug used to slow kidney disease found to be ineffective
Following a major clinical trial, clinicians find the drug allopurinol does not prevent worsening of kidney disease. The Australasian Kidney Trials Network led a large, two-year study, known as CKD-FIX, to assess the effectiveness of allopurinol, in slowing the rate…
Antibodies against sugars, internal radiation: Powerful package against cervical cancer
The sugar coating on cancer cells helps them thrive, and a new study indicates patients with cervical cancer who make antibodies to those sugars appear to do better when they also receive internal radiation therapy. Scientists looked in the blood…
Antibodies against sugars, internal radiation: Powerful package against cervical cancer
The sugar coating on cancer cells helps them thrive, and a new study indicates patients with cervical cancer who make antibodies to those sugars appear to do better when they also receive internal radiation therapy. Scientists looked in the blood…
Synthesized cell culture process sets stage for more efficient cancer research
Researchers in Japan have replicated cancer cells from diseased bladder tissue in dogs, minimizing the use of costly stem cell products. The synthesized tumor cells allow scientists to diagnose cancer and optimize treatment without putting the patient through tiresome rigors…
Synthesized cell culture process sets stage for more efficient cancer research
Researchers in Japan have replicated cancer cells from diseased bladder tissue in dogs, minimizing the use of costly stem cell products. The synthesized tumor cells allow scientists to diagnose cancer and optimize treatment without putting the patient through tiresome rigors…
High uric acid levels benefit women’s lungs in aging and disease
Researchers at Kumamoto University in Japan have discovered that uric acid, an antioxidant, protects against declining lung function from age or lung disease, especially in women. High uric acid levels can cause health problems such as gout and renal damage,…
Discovery of a novel gene involved in DNA damage repair and male fertility
A research group from the Institute of Molecular Embryology and Genetics (IMEG) at Kumamoto University, Japan has discovered that the gene C19ORF57 plays a critical role in meiosis.
Inherited mutation linked to higher prostate cancer risk in African American families
Keck School of Medicine researchers have identified a variant in the genome that may explain why multiple men in the same family develop the disease — and could serve as a guide for screening
Unique ‘home built’ device provides fast disease analysis in kidneys affected by diabetes
WASHINGTON — The amount of scarring in damaged kidneys as a result of diabetes or acute injury, is a key factor in determining treatment. But it has not been possible, using traditional techniques, to quickly and accurately assess how widespread…
Immunotherapy improves survival in patients with advanced bladder cancer
An immunotherapy drug ‘avelumab’ significantly improves survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Queen Mary University of London & Barts Cancer Centre
Unique ‘home built’ device provides fast disease analysis in kidneys affected by diabetes
WASHINGTON — The amount of scarring in damaged kidneys as a result of diabetes or acute injury, is a key factor in determining treatment. But it has not been possible, using traditional techniques, to quickly and accurately assess how widespread…
Immunotherapy improves survival in patients with advanced bladder cancer
An immunotherapy drug ‘avelumab’ significantly improves survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Queen Mary University of London & Barts Cancer Centre
New urine testing method holds promise for kidney stone sufferers
Simpler test that can be done in doctor’s office offers results in 30 minutes
Combination of chemo and immunotherapy is shown to work against metastatic bladder cancer
New York, NY (May 14, 2020) – A clinical trial led by Mount Sinai researchers has showed for the first time that combining chemotherapy and immunotherapy can slow down metastatic bladder cancer. The trial also showed that immunotherapy alone may…
Combination of chemo and immunotherapy is shown to work against metastatic bladder cancer
New York, NY (May 14, 2020) – A clinical trial led by Mount Sinai researchers has showed for the first time that combining chemotherapy and immunotherapy can slow down metastatic bladder cancer. The trial also showed that immunotherapy alone may…
Microbiome therapy protects against recurrent bacterial vaginosis
Reducing this common infection could help prevent HIV and preterm birth
Microbiome therapy protects against recurrent bacterial vaginosis
Reducing this common infection could help prevent HIV and preterm birth
Clinical characteristics, results of semen tests among men with COVID-19
What The Study Did: The clinical characteristics of men with coronavirus disease 2019 (COVID-19) whose semen tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are examined in this observational study. Authors: Weiguo Zhao, M.D., of the Eighth Medical…
Clinical characteristics, results of semen tests among men with COVID-19
What The Study Did: The clinical characteristics of men with coronavirus disease 2019 (COVID-19) whose semen tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are examined in this observational study. Authors: Weiguo Zhao, M.D., of the Eighth Medical…
Androgen-deprivation treatments for prostate cancer could protect men from COVID-19
A study of 4532 men in the Veneto region of Italy has found that those who were being treated for prostate cancer with androgen-deprivation therapies (ADT) were less likely to develop the coronavirus COVID-19 and, if they were infected, the…
Blood filter may calm the cytokine storm of COVID-19
Cytokine storms created by COVID-19 are causing major organ destruction and death, and for the first time in the United States, when patients begin to show signs of trouble, physicians are replacing the usual filter in a kidney dialysis machine…
NUS researchers develop novel device to improve performance of underactive bladders
New device can be attached to the bladder to provide real-time volume detection and efficient voiding capabilities
Blood filter may calm the cytokine storm of COVID-19
Cytokine storms created by COVID-19 are causing major organ destruction and death, and for the first time in the United States, when patients begin to show signs of trouble, physicians are replacing the usual filter in a kidney dialysis machine…
NUS researchers develop novel device to improve performance of underactive bladders
New device can be attached to the bladder to provide real-time volume detection and efficient voiding capabilities
A world first: Assessing kidney quality before transplantation using photoacoustic imaging
Researchers discover non-invasive method to visualize damage in donor kidneys – empowering doctors to match kidney quality with patient life expectancy for longer-lasting transplantation outcomes.
A world first: Assessing kidney quality before transplantation using photoacoustic imaging
Researchers discover non-invasive method to visualize damage in donor kidneys – empowering doctors to match kidney quality with patient life expectancy for longer-lasting transplantation outcomes.