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UrduAfter years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet in Sweden provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are published in the scientific journal Nature Communications , open…
Tag: PHARMACEUTICAL/COMBINATORIAL CHEMISTRY
Accelerated speed of discovery could lead to more effective smoking cessation aids
As smokers know all too well, nicotine is highly addictive. It’s hard to quit smoking, a habit that claims the lives of more than seven million people each year. Smoking tobacco delivers nicotine to the neuroreceptors responsible for addiction, affecting…
Accelerated speed of discovery could lead to more effective smoking cessation aids
As smokers know all too well, nicotine is highly addictive. It’s hard to quit smoking, a habit that claims the lives of more than seven million people each year. Smoking tobacco delivers nicotine to the neuroreceptors responsible for addiction, affecting…
Accelerated speed of discovery could lead to more effective smoking cessation aids
As smokers know all too well, nicotine is highly addictive. It’s hard to quit smoking, a habit that claims the lives of more than seven million people each year. Smoking tobacco delivers nicotine to the neuroreceptors responsible for addiction, affecting…
Deep learning, 3D technology to improve structure modeling, create better drugs
WEST LAFAYETTE, Ind. – Proteins are often called the working molecules of the human body. A typical body has more than 20,000 different types of proteins, each of which are involved in many functions essential to human life. Now, Purdue…
A new effort to tackle tuberculosis
Researchers at the University of Dundee are aiming to make a breakthrough against tuberculosis, backed by a $3 million grant from the Bill & Melinda Gates Foundation
A new effort to tackle tuberculosis
Researchers at the University of Dundee are aiming to make a breakthrough against tuberculosis, backed by a $3 million grant from the Bill & Melinda Gates Foundation
Beiersdorf and Insilico employ AI technology in computer-simulated skin research
Beiersdorf uses artificial intelligence to accelerate the discovery of novel and safe active ingredients New molecules for a specific skin indication to be generated and analyzed using next-generation artificial intelligence developed by Insilico Medicine Beiersdorf is a leader in the…
Beiersdorf and Insilico employ AI technology in computer-simulated skin research
Beiersdorf uses artificial intelligence to accelerate the discovery of novel and safe active ingredients New molecules for a specific skin indication to be generated and analyzed using next-generation artificial intelligence developed by Insilico Medicine Beiersdorf is a leader in the…
This ‘lemon’ could help machine learning create better drugs
WEST LAFAYETTE, Ind. – One of the challenges in using machine learning for drug development is to create a process for the computer to extract needed information from a pool of data points. Drug scientists must pull biological data and…
This ‘lemon’ could help machine learning create better drugs
WEST LAFAYETTE, Ind. – One of the challenges in using machine learning for drug development is to create a process for the computer to extract needed information from a pool of data points. Drug scientists must pull biological data and…
Reflecting on the year in chemistry
A lot can happen in a year, especially when it comes to science. As 2019 draws to a close, Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, is highlighting the year’s biggest stories in chemistry,…
The fifth volume of Frontiers in Natural Product Chemistry is now published
Frontiers in Anti-Infective Agents is a book series that focuses on antibiotics and vaccines, both current and new
Reflecting on the year in chemistry
A lot can happen in a year, especially when it comes to science. As 2019 draws to a close, Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, is highlighting the year’s biggest stories in chemistry,…
The fifth volume of Frontiers in Natural Product Chemistry is now published
Frontiers in Anti-Infective Agents is a book series that focuses on antibiotics and vaccines, both current and new
NICE recommends Vifor Pharma’s Veltassa® (patiromer)
A positive final appraisal determination (FAD) for Veltassa® (patiromer) recommends patients in England have access to a new treatment option for treating hyperkalaemia (raised serum potassium levels) in adults 1 Hyperkalaemia is a serious condition, which has a negative impact…
NICE recommends Vifor Pharma’s Veltassa® (patiromer)
A positive final appraisal determination (FAD) for Veltassa® (patiromer) recommends patients in England have access to a new treatment option for treating hyperkalaemia (raised serum potassium levels) in adults 1 Hyperkalaemia is a serious condition, which has a negative impact…
Developing next-generation biologic pacemakers
Stem cells originally found in fat converted to pacemaker-like cells
Developing next-generation biologic pacemakers
Stem cells originally found in fat converted to pacemaker-like cells
How light a foldable and long-lasting battery can be?
With the launch of wearable devices and smartphones that require high capacity of electricity such as foldable phones and 5G phones, the interest in batteries are increasing and various battery types are developed. For example, flexible batteries embedded in the…
Tropical flower offers potential new route for treating pancreatic cancer
An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat deadly pancreatic cancer. Pancreatic cancer is…
How light a foldable and long-lasting battery can be?
With the launch of wearable devices and smartphones that require high capacity of electricity such as foldable phones and 5G phones, the interest in batteries are increasing and various battery types are developed. For example, flexible batteries embedded in the…
Tropical flower offers potential new route for treating pancreatic cancer
An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat deadly pancreatic cancer. Pancreatic cancer is…
She uses mushroom enzyme and light to create green chemicals
By combining nature’s own reactions, Associate Professor Selin Kara from the Department of Engineering at Aarhus University aims to develop a fully green and sustainable production process for chemicals.
The next step in organ transplants: New startup takes aim at reperfusion injury
Charleston, SC-based Lydex Pharmaceuticals has received a small business technology transfer grant from the NIH to investigate and develop compounds targeting key enzymes responsible for organ damage, inflammation and rejection after transplant
Cutting nanoparticles down to size — new study
A new technique in chemistry could pave the way for producing uniform nanoparticles for use in drug delivery systems. Scientists have been investigating how to make better use of nanoparticles in medicine for several decades. Significantly smaller than an average…
Key to rubustness of plants discovered
In every weather situation, plants need to be robust and flexible at the same time. These structural properties come from its cell wall: It’s responsible to keep the plant in shape, to compensate its osmotic pressure and to protect it…
Using fungi to search for medical drugs
An enormous library of products derived from more than ten thousand fungi could help us find new drugs. Researchers from the group of Jeroen den Hertog at the Hubrecht Institute , in collaboration with researchers from the Westerdijk Institute and…
We love coffee, tea, chocolate and soft drinks so much, caffeine is literally in our blood
CORVALLIS, Ore. – Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body. In conducting mass…
Key to rubustness of plants discovered
In every weather situation, plants need to be robust and flexible at the same time. These structural properties come from its cell wall: It’s responsible to keep the plant in shape, to compensate its osmotic pressure and to protect it…
Using fungi to search for medical drugs
An enormous library of products derived from more than ten thousand fungi could help us find new drugs. Researchers from the group of Jeroen den Hertog at the Hubrecht Institute , in collaboration with researchers from the Westerdijk Institute and…
We love coffee, tea, chocolate and soft drinks so much, caffeine is literally in our blood
CORVALLIS, Ore. – Scientists at Oregon State University may have proven how much people love coffee, tea, chocolate, soda and energy drinks as they validated their new method for studying how different drugs interact in the body. In conducting mass…
New flu drug drives drug resistance in influenza viruses
MADISON – On January 31, 2019, an 11-year old boy in Japan went to a medical clinic with a fever. The providers there diagnosed him with influenza, a strain called H3N2, and sent him home with a new medication called…
New flu drug drives drug resistance in influenza viruses
MADISON – On January 31, 2019, an 11-year old boy in Japan went to a medical clinic with a fever. The providers there diagnosed him with influenza, a strain called H3N2, and sent him home with a new medication called…
Heating techniques could improve treatment of macular degeneration
Macular degeneration can lead to vision loss, with treatments sometimes ineffective; this may be improved with thermally induced fluid mixing
Nine young scientists obtain funding from Russian Foundation for Basic Research
The allocated sums are 4 to 6 million rubles, and the duration is 2 years
UTSA to unlock the power of sulfur in future drug design
Organosulfur compounds are widely present in our bodies and the natural environment. They are found in onions, shallots and even cauliflower. Medical research finds that when consumed, they can protect against cancer, heart disease and even diabetes. There is also…
The good side of carbon monoxide
Most people think of carbon monoxide as harmful, and with good reason — the colorless, odorless gas sends 50,000 people in the U.S. to hospitals each year when their furnaces malfunction or car engines run in poorly ventilated spaces. But…
Dozens of potential new antibiotics discovered with free online app
CHAMPAIGN, Ill. — A new web tool speeds the discovery of drugs to kill Gram-negative bacteria, which are responsible for the overwhelming majority of antibiotic-resistant infections and deaths. The tool also offers insights into discrete chemical changes that can convert…
New catalysts remove NOx pollutants at lower temperatures
Bulk ‘defective’ vanadium oxide for NOx removal from industrial exhaust at temperatures lower than 150 degrees Celsius
FDA awards $1.7 million to IU and other universities for quality management research
BLOOMINGTON, Ind. — The U.S. Food and Drug Administration has awarded $1.7 million to five universities, including Indiana University, for a wide-ranging research project designed to help the agency better understand how to employ its quality management resources when inspecting…
FDA awards $1.7 million to IU and other universities for quality management research
BLOOMINGTON, Ind. — The U.S. Food and Drug Administration has awarded $1.7 million to five universities, including Indiana University, for a wide-ranging research project designed to help the agency better understand how to employ its quality management resources when inspecting…
Electrochemistry amps up in pharma
Sparked by several high-profile reports, electrochemistry — using electricity to perform chemical reactions like oxidation and reduction — is gaining popularity in the pharmaceutical field. Some researchers have embraced the technology as a tool to synthesize compounds that are difficult…
‘Vaping’: The BfR advises against self-mixing e-liquids
E-cigarette consumers should avoid products of uncertain origin
Brain cancer-detecting innovation by CCNY researchers receives two US patents
Raising hopes of rapid and more specific brain cancer diagnoses, a new “Resonance Raman” technique developed by world-renowned physicist Robert R. Alfano and his IUSL research group at The City College of New York is the recipient of two U.S.…
Hospital disinfectants struggling to kill C. diff bacteria colonies
Clorox comes close, but none completely eliminates superbug
Electrochemistry amps up in pharma
Sparked by several high-profile reports, electrochemistry — using electricity to perform chemical reactions like oxidation and reduction — is gaining popularity in the pharmaceutical field. Some researchers have embraced the technology as a tool to synthesize compounds that are difficult…
‘Vaping’: The BfR advises against self-mixing e-liquids
E-cigarette consumers should avoid products of uncertain origin
Brain cancer-detecting innovation by CCNY researchers receives two US patents
Raising hopes of rapid and more specific brain cancer diagnoses, a new “Resonance Raman” technique developed by world-renowned physicist Robert R. Alfano and his IUSL research group at The City College of New York is the recipient of two U.S.…
Hospital disinfectants struggling to kill C. diff bacteria colonies
Clorox comes close, but none completely eliminates superbug