Salk researchers made new inroads into understanding how the commonly prescribed drug metformin works in the body
Tag: METABOLISM/METABOLIC DISEASES
American Heart Association honors UVA endocrinologist for high blood pressure work
Robert M. Carey, MD, Professor of Medicine at the University of Virginia School of Medicine, has been named a Distinguished Scientist of the American Heart Association for his “extraordinary contributions” to cardiovascular research. Carey, a former dean of the school,…
Linking calorie restriction, body temperature and healthspan
A new study reveals that reduced body temperature plays a major role in initiating the extensive health benefits of calorie-restricted diets.
‘One size fits all’ medication approach doesn’t work in pregnancy
New research led by the University of South Australia shows that a blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk for the rest of their lives. UniSA and New Zealand fetal physiologists say…
Probiotics may help manage childhood obesity
Conference abstract, observational, people
The brain can induce diabetes remission in rodents, but how?
Fibroblast growth factor 1 effects on specific brain cell types, and on nets that enmesh neurons, inform how it restores blood sugar levels to normal in diabetic animals
New weight-loss hope for those with highest obesity risk: Underserved, low-income patients
Low-income Louisiana patients enrolled in a tailored obesity intervention program lost much more weight than counterparts receiving usual care.
Offspring of mice fed imbalanced diets shown to be neurologically ‘programmed’ for obesity
Pregnant mice fed a diet high in omega-6 fats and low in omega-3 fats produce offspring that go on to exhibit “hedonic”–pleasurable but excessive–levels of consumption of hyper-caloric diets, according to researchers at Hiroshima University. Omega-6 fats are found in…
New weight-loss hope for those with highest obesity risk: Underserved, low-income patients
Patients in primary care clinic program lost 5 percent of body weight
Two ERC Starting Grants for MDC scientists
ERC funding for pioneering research
Minimally invasive ellipsys system allows kidney patients to begin dialysis sooner
New study has important patient safety implications, as shortening dialysis timeline reduces reliance on riskier vascular access procedures
Handgrip strength shown to identify people at high risk of type 2 diabetes
Findings demonstrate handgrip strength could be a cost-effective early screening tool
Finding cortisone alternatives with fewer side effects
DNA binding is essential for effectiveness of steroids
Protein discovery could improve type 2 diabetes treatment
A world first discovery of how a protein works in the liver could lead to a more effective type 2 diabetes drug.
A naturally-occurring metabolite ups lifespan and compresses late-life morbidity in mice
Alpha-ketaglutarate dramatically improves several measures of healthspan in double-blind study
Cholesterol drug combinations could cut health risk for European patients
New findings from a large European study of patients in 18 countries, including the UK, show that while many patients are able to reduce their risk through taking statins, those at the highest risk of cardiovascular events may benefit from…
A surprising protein player in diabetes
A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) and Riken Center of Integrative…
Cardiac biomarker shows stronger associations with kidney disease progression than BP
The primary goal of this study by Amanda H. Anderson et al was to identify independent risk factors of CKD progression among participants with and without diabetes in a prospective CKD cohort study (N=3,379). Among those with diabetes, CKD progression…
Obesity linked with higher risk for COVID-19 complications
A review of COVID-19 studies reveals a troubling connection between two health crises: coronavirus and obesity.
Consuming your own fecal microbiome when dieting may limit weight regain — Ben-Gurion University
Injesting frozen capsules as part of a green-mediterranean diet supplemented with Mankai
Obesity linked with higher risk for COVID-19 complications
UNC-Chapel Hill study raises concern that COVID-19 vaccine will be less effective for those with obesity
Transplanted brown-fat-like cells hold promise for obesity and diabetes
Studies in mice offer a proof of concept that ‘HUMBLE’ cells, created from human white fat, can treat metabolic diseases
Artificial pancreas effectively controls type 1 diabetes in children age 6 and up
A clinical trial at four pediatric diabetes centers in the United States has found that a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — is safe and effective at managing blood glucose levels in…
Metabolic syndrome linked to worse outcomes for COVID-19 patients
Patients hospitalized with COVID-19 were over three times more likely to die if they had metabolic syndrome
Dr. Daniel Pinto named winner of the 2020 ESCEO-IOF Pierre Meunier Young Scientist Award
The prestigious annual Award recognizes young investigators in the field who have demonstrated outstanding scientific merit early in their careers
IOF CNS Medal awarded to Dr. Famida Jiwa, President and CEO of Osteoporosis Canada
The International Osteoporosis Foundation (IOF) has recognized Dr. Jiwa for major contributions to the IOF Committee of National Societies (CNS), as well as her longstanding dedication to osteoporosis awareness, education and advocacy.
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‘Selfies’ could be used to detect heart disease
Sending a “selfie” to the doctor could be a cheap and simple way of detecting heart disease, according to the authors of a new study published today (Friday) in the European Heart Journal
Study to ID brain neurons that control metabolism
Results could lead to new medications, diets that improve health
A gatekeeper against insulin resistance in the brain
The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive. A group of scientists at Helmholtz…
‘Selfies’ could be used to detect heart disease
New research uses artificial intelligence to analyse facial photos
New research on Post-fracture Care Coordination Programs highlighted at WCO-IOF-ESCEO
World experts in the field of osteoporosis focus on secondary fracture prevention, with sessions dedicated to healthcare policy change, post-fracture care services, and development of a tool to assess the cost-saving impact of Fracture Liaison Services
First IOF Skeletal Rare Diseases Academy Awards recognize research excellence
Today, at the 2020 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, five young investigators were awarded the first International Osteoporosis Foundation (IOF) Skeletal Rare Diseases Academy Awards in recognition of the quality of their research related to rare disorders…
Genetic background influences disease risk from single-gene variants
In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk
Yale-led surgical innovation promises better dialysis outcomes
New Haven, Conn. — A new technique developed by a Yale-led research team improves blood flow in surgically made blood vessels used in dialysis, enables them to last longer, and results in fewer complications than the standard technique. The findings,…
2020 ESCEO-IOF Herbert Fleisch Medal awarded to Dr Stefania Maggi
Dr Maggi, a leading geriatrician and epidemiologist, was awarded the prestigious Herbert A. Fleisch ESCEO-IOF Medal during the opening ceremony of the virtual World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
IOF Medal Of Achievement 2020 awarded to Dr Basel Masri
Prestigious annual award underlines the International Osteoporosis Foundation’s (IOF) mission to increase understanding and awareness of osteoporosis and to promote medical innovation in the field
IOF President’s Award honours global experts for commitment to IOF and the bone field
Professor Maria-Luisa Brandi, Dr Lee Joon-Kiong and Professor Ego Seeman have been awarded the 2020 International Osteoporosis Foundation (IOF) President’s Award for extraordinary contributions to the advancement of IOF programmes and to the bone field
Research shows air pollution could play role in development of cardiometabolic diseases
First-of-its-kind study, based on a mouse model, finds living in a polluted environment could be comparable to eating a high-fat diet, leading to a pre-diabetic state
IOF announces launch of Skeletal Rare Diseases Academy
New International Osteoporosis Foundation (IOF) initiative will support communication, educational programmes and research advances in rare disorders of bone.
Virtual IOF-ESCEO World Congress draws record attendance
The CME-accredited WCO-IOF-ESCEO 2020, from August 20-22, will feature more than 210 live and pre-recorded sessions covering new clinical research and advances in the field of osteoporosis, osteoarthritis and musculoskeletal diseases.
First immune-evading cells created to treat type 1 diabetes
Salk researchers develop transplantable human cells that make insulin, controlling blood sugar without immunosuppressants in mouse models
Major weight loss — whether from surgery or diet — has same metabolic benefits
For severely obese, it’s the weight loss alone that drives improvements such as remission of diabetes
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High fructose diet in pregnancy impacts metabolism of offspring, study finds
An increased level of fructose intake during pregnancy can cause significant changes in maternal metabolic function and milk composition and alter the metabolism of their offspring, researchers from the University of Otago, Wellington, have found.
How protein protects against fatty liver
Non-alcoholic fatty liver disease is the most common chronic liver disease in the world, with sometimes life-threatening consequences. A high-protein, calorie-reduced diet can cause the harmful liver fat to melt away – more effectively than a low-protein diet. A new…
Risk of diabetes complications increases with elevated levels of NT-proBNP
Healthy people – especially women – with elevated levels of the heart failure marker NT-proBNP have a lower risk of developing type 2 diabetes. However, if these people develop diabetes nonetheless, they are more likely to suffer from macro- and…
Is turning back the clock in aging fat cells a remedy for lifestyle diseases?
Researchers led by Osaka University find that reversing age-related changes in fat cells may prevent the development of lifestyle diseases such as diabetes and fatty liver
High fructose diet in pregnancy impacts metabolism of offspring, study finds
An increased level of fructose intake during pregnancy can cause significant changes in maternal metabolic function and milk composition and alter the metabolism of their offspring, researchers from the University of Otago, Wellington, have found. The research, which was led…
Low ‘good’ cholesterol levels found in Latin America and the Caribbean
New findings suggest low levels of HDL cholesterol are the most common kind of lipid disorder in Latin America and the Caribbean
Drugs against alpha-ketoglutarate may combat deadly childhood brain tumor
NIH funded pre-clinical study highlights intricate links between brain tumors and cancer cell metabolism
Autism-cholesterol link
New research reveals a subtype of autism associated with lipid abnormalities