English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduA researcher at the University of Virginia School of Medicine is testing what he calls a “radically different” approach to managing type 2 diabetes for those who can’t or don’t want to lose weight. Daniel Cox, PhD, professor of psychiatry…
Tag: METABOLISM/METABOLIC DISEASES
In liver, a stressed cell can be bad news for its neighbors
Findings provide new insights into obesity, diabetes, and fatty liver disease
New drug molecules hold promise for treating rare inherited terminal childhood disease
Scientists at the University of Exeter have identified a way to “rescue” cells that have genetically mutated, paving the way to a possible new treatment for rare terminal childhood illness such as mitochondrial disease. The research, funded by the United…
New screening platform leads to discovery of next-generation prodrugs for type 1 diabetes
Zinc-binding prodrug may mitigate type 1 diabetes mellitus β-cell depletion
Water may be an effective treatment for metabolic syndrome
Water suppresses vasopressin, a hormone linked to obesity, diabetes
Why does exercise make some people healthier than others?
The answers may lie in how the power plants of your cells react to physical activity
Research shows impact of bariatric surgery on cardiovascular disease risk in obese teens
Five-year study by Children’s Hospital Colorado researchers published in Surgery for Obesity and Related Diseases
Grant gives scientists chance to advance tools to predict readmission in diabetic patients
(Philadelphia, PA) – Each year in the United States, more than 1 million patients with diabetes make return trips to the hospital for diabetes-related illness, often being readmitted within 30 days of their initial hospitalization. The costs of these return…
New nationwide collaborative study to determine factors that predict disease severity and long-term health impacts of COVID-19
Researchers at CU Anschutz are part of the 37 academic medical center cohort
USC-led researchers develop new way to watch pancreatic cells package insulin
For the first time, scientists have peered deeply inside a pancreatic cell and observed it packaging insulin and responding to a drug treatment, an intimate look at the mechanisms responsible for preventing diabetes . A team of scientists — led…
Sous vide cooking method makes beef protein more digestible
Once used to prepare cuisine in only the finest restaurants, sous vide is now making its way into home chefs’ kitchens. French for “under vacuum,” the technique involves vacuum sealing food in a plastic pouch and then slowly cooking it…
Targeting T cell protein could prevent type 1 diabetes, study suggests
Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes. The study, which will be published December 9 in the Journal of Experimental Medicine ( JEM ), reveals…
The gut microbiome in polycystic ovary syndrome and its association with metabolic traits
University of Tartu researchers and their collaborators from Finland and Spain investigated the relationship between the gut microbiome and polycystic ovary syndrome. Their study revealed that women with polycystic ovary syndrome in their late reproductive years have significant microbial changes…
Lipid identified in human breast milk may play important role in early childhood weight
A lipid metabolite called 12,13-diHOME is in human breast milk and appears to be associated with beneficial infant weight gain and body composition in the early postnatal period.
More years of obesity means higher risk of disease, study finds
A greater obesity duration is associated with worse values for all cardiometabolic disease factors, according to a new study published this week in PLOS Medicine by Tom Norris of Loughborough University, UK, and colleagues. People with obesity do not all…
Arctic ground squirrels recycle nutrients to endure deep hibernation
By studying the body chemistry of hibernating Arctic ground squirrels, researchers have found that the animals are able to recycle their body’s own nutrients to survive during a long, inactive winter. A University of Alaska Fairbanks-led study monitored ground squirrels…
Participation in competitive sport in adolescence brings midlife health benefits to women
Higher lean mass and bone density and better physical performance at midlife were associated with competitive sport participation at the age of 13 to 16 years
The Mediterranean diet reduces the risk of having another heart attack
Heart disease is the main cause of death in developed countries.
Grant boosts Louisiana children’s access to clinical trials
Federal program could improve health for all children in the state, country
New study debunks blood type diet
ABO blood types benefit similarly from plant-based diet, according to research published in the Journal of the Academy of Nutrition and Dietetics
Hidden structure found in essential metabolic machinery
Discovery ‘requires us to rethink everything we thought we knew about peroxisomes’
Better diabetes treatment: New insulin molecule can self-regulate blood sugar
Researchers from the University of Copenhagen and biotech firm Gubra have developed a new insulin molecule that will make blood sugar regulation both easier and safer for those with type 1 diabetes
Blackcurrants are favorable for glucose metabolism
Blackcurrants have a beneficial effect on post-meal glucose response, and the required portion size is much smaller than previously thought, a new study from the University of Eastern Finland shows. Blackcurrants have a beneficial effect on the blood glucose response…
‘Artificial Pancreas Dashboard’ to standardize hybrid closed-loop reporting
New Rochelle, NY, November 30, 2020–A standardized “Artificial Pancreas (AP) Dashboard” should provide easy to use single-page hybrid closed-loop system (HCL) reporting for insulin requiring patients with diabetes. The AP Dashboard will help standardize HCL reporting similar to standardized CGM…
Molecule that regulates muscle adaptation to exercise is discovered
An article in Cell shows that the metabolite succinate is released by muscle cells during physical exercise and triggers a process of tissue remodeling that makes muscles stronger and enhances metabolic efficiency
Obesity changes cell response to glucose, uses slower metabolic path in mouse liver
Trans-omic network shows obese mice modeling Type 2 diabetes chart a different path for responding to glucose than healthy peers
Lab results don’t explain ‘obesity paradox,’ but bias may
AUGUSTA, Ga. (Dec.1, 2020) – Results of standard laboratory tests performed on adult outpatients to provide an overall picture of their health are fairly consistent between those with obesity and their leaner counterparts, investigators report. The finding negates one rationale…
Gut microbes: a key to normal sleep
With fall and winter holidays coming up, many will be pondering the relationship between food and sleep.
Early weight gain in children linked to ability to produce the hormone leptin
Young children of African ancestry are more at risk of developing obesity if they possess a genetic variant that reduces their ability to produce the hormone leptin. Adults with the variant do not have the same risk, suggesting that leptin…
New targeted therapy blocks metabolism in brain cancer cells with genetic vulnerability
Preclinical study shows early activity of enolase inhibitors in cancer cells with genetic loss of ENO1
Adipose tissue may be the source of inflammatory factors that aggravate COVID-19
Preliminary results of patient tissue analysis show that the virus infects adipocytes and alters the quantity of signaling molecules released by these cells into the bloodstream
New podcast series reveals the truth about hormones and health
Hormones: The Inside Story is a brand new podcast series uncovering the facts about hormones and health using an expert-led, myth-busting and often amusing format. Hormones affect stress, sleep, body fat, fertility and almost every aspect of our daily lives…
Are high-protein total diet replacements the key to maintaining healthy weight?
Study results published in The American Journal of Clinical Nutrition suggest that these diets are a promising nutritional strategy to combat rising rates of obesity
Diabetes increases neuritic damage around amyloid plaques in Alzheimer’s disease
New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer’s disease (AD). In an AD mouse model, diabetes induced through a diet rich in fats and sugars weakened the…
The gut microbiota forms a molecule that can contribute to diabetes progression
It is the bacterial changes in the gut that increase the levels of imidazole propionate, the molecule that makes the body’s cells resistant to insulin in type 2 diabetes. This result emerges from a European study, MetaCardis. The gut and…
Good long-term effects of continuous glucose monitoring
New data on continuous glucose monitoring for people with type 1 diabetes, over a significantly longer period than before, are now available. A University of Gothenburg study shows that using the CGM tool, with its continuous monitoring of blood sugar…
Chronic inflammation causes a reduction in NAD+
Buck Institute research links hallmarks of aging: senescent cells activate CD38 which degrades NAD+, a key metabolite implicated in age-related decline
New Fred Hutch-led trial shows no benefits of dairy foods for blood sugar regulation
Findings published in the American Journal of Clinical Nutrition are in contrast to many observational studies suggesting dairy intake may reduce risk of Type 2 diabetes
Bursts of exercise can lead to significant improvements in indicators of metabolic health
A new study identifies potential mechanisms that could contribute to a better understanding of cardiometabolic benefits of exercise.
Changes to the brain’s reward system may drive overeating in mice
Innate and diet-induced changes in reward area may explain why some mice are prone to overeat
Computer vision app allows easier monitoring of diabetes
A computer vision technology developed by University of Cambridge engineers has now been developed into a free mobile phone app for regular monitoring of glucose levels in people with diabetes. The app uses computer vision techniques to read and record…
A few kilograms weight loss nearly halves the risk of diabetes
Peer reviewed – Randomised Controlled Trial – People
Diabetes drug can treat and reverse heart failure and reduce
Empagliflozin, a recently developed diabetes drug, can effectively treat and reverse heart failure in both diabetic and non-diabetic patients, according to researchers at the Icahn School of Medicine at Mount Sinai. Their clinical trial showed that this medication can improve…
In mice, cadmium exposure during pregnancy linked to obesity in female offspring
In a mouse study aimed at modeling human exposure to the toxic metal cadmium, researchers from North Carolina State University found that female offspring of mice exposed to cadmium during pregnancy became obese in adulthood, developed fatty livers and could…
Continuity determines whether physical activity on prescription works for the least active
Ongoing support for several years and focus on the individual. These are success factors that make physical activity on prescription a workable concept for patients, including those who, after six months, have not reached their desired physical activity level, a…
Racial disparities in pediatric diabetes treatment
PHILADELPHIA (November 12, 2020) – Type 1 diabetes (T1D) is the third most common pediatric chronic disease in the United States, and the risk of the disease has risen sharply in non-Hispanic Black (NHB) children in the last 20 years,…
New European consensus on management of osteoporosis in advanced chronic kidney disease
This landmark consensus addresses the unacceptable osteoporosis care gap in patients with chronic kidney disease stages G4-G5D; it provides practical recommendations to support pro-active fragility fracture prevention in these high-risk patients
Internal clocks drive beta cell regeneration
Scientists from UNIGE and HUG identify the essential role of circadian clocks in the regeneration of insulin-producing cells.
A molecule from gut bacteria reduces effect of diabetes medication
The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, can be blocked by a molecule from the bacteria in our intestines, a University of Gothenburg study shows. Metformin is the primary treatment option for…
Chemicals in your living room cause diabetes
A new UC Riverside study shows flame retardants found in nearly every American home cause mice to give birth to offspring that become diabetic.