UW Medicine researchers compared vaginal samples collected from 95 young women or adolescent study participants in Kenya before or after they began having sexual intercourse. They found a sharp increase in proteins that control the immune response, including IL-1β, IL-2, and CXCL8, during the first year after becoming sexually active.
Tag: Immune activation
Vaginal immune system may hint at prime vaccine timing
A meta-analysis of 32 studies showed that the immune system within the vagina ebbs and flows, depending on menstrual-cycle stage. The analysis identified 53 distinct messages that immune cells sent to one another.
Understanding gut inflammation may hold clues to mitigating Parkinson’s onset
GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche.
Study says inflammation seen in earliest stages of Parkinson’s disease, and it is different between men and women
New research shows evidence of inflammation in the blood of Parkinson’s disease patients during the earliest stages of the disease, lending support to theories that inflammation is a major driver of PD. The study also points out differences between the sexes in the symptoms and course of the disease.
Scientists Discover How the Body Fights Viruses That Try to Evade the Immune System Response
Scientists have discovered a molecular pathway that counteracts the ability of some viruses to evade the immune response. The findings raise hope in generating better immune responses to viral infections, such as COVID-19, as well as to cancer.
Scientists identify “immune cop” that detects SARS-CoV-2
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it’s time to mount an antiviral response.
UCLA scientists develop method to more efficiently isolate and identify rare T cells
Scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a technique that will enable researchers to more efficiently isolate and identify rare T cells that are capable of targeting viruses, cancer and other diseases.
ORNL researcher studies individualized isotopes’ impact by targeting cancer
A radioisotope researcher in the Radioisotope Science and Technology Division at the Department of Energy’s Oak Ridge National Laboratory, Davern is focusing on ways to use nanoparticles — particles 100 nanometers or smaller that can have special properties — to contain those radioisotopes and deliver them directly to cancer cells, where they can decay into different isotopes that irradiate those cells.
New University of Kentucky study could change what we know about platelets
The $6.6 million study will focus on how platelets function when they form clots in blood vessels and when they sense circulating pathogens, like viruses.
Too Much Haste Leads to Little Speed
Researchers at the La Jolla Institute for Immunology (LJI) have written a new first draft chapter in the book of immunology. They have discovered a protective biological switch that, briefly, turns on the immune response at the first whiff of an invader—an important feature—but can also turn off potentially destructive immune rampage that may also occur. This “off” switch can protect against serious, life threatening inflammation.
Flickering Light Mobilizes Brain Chemistry That May Fight Alzheimer’s
The promise of flickering light to treat Alzheimer’s takes another step forward in this new study, which reveals stark biochemical mechanisms: The 40 Hertz stimulation triggers a marked release of signaling chemicals.
Wound healing in mucous tissues could ward off AIDS
Some primates can carry SIV, a virus resembling HIV, lifelong and yet not develop AIDS. They are able to repair SIV damage to intestinal mucous tissues and avoid escape of gut bacteria and other events leading to immune system exhaustion. The findings offer clues for new HIV treatments