CHOP Researchers Develop Novel Approach to Capture Hard-to-View Portion of Colon in 3-D for the First Time

In a groundbreaking discovery, researchers at Children’s Hospital of Philadelphia (CHOP) developed a new imaging method that allows scientists to view the enteric nervous system (ENS) – a key part of the human colon – in three dimensions by making other colon cells that normally block it invisible. The ENS has previously only been visible in thin tissue slices that provide limited clinical information.

Study: Bariatric surgeries can double peak blood alcohol levels, patients may be unaware

CHAMPAIGN, Ill. — A new study of 55 women found that two of the most popular forms of bariatric surgery – Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy – may dramatically change patients’ sensitivity to and absorption of alcohol. Some…

Poop matters: Making the mouse gut microbiome more human-like

There is a growing consensus that the gut microbiome is involved in many aspects of physical and mental health, including the onset of Parkinson’s disease, multiple sclerosis, and even some behaviors. The microbiota of the small intestine in particular are…

Study: Bariatric surgeries can double peak blood alcohol levels, patients may be unaware

CHAMPAIGN, Ill. — A new study of 55 women found that two of the most popular forms of bariatric surgery – Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy – may dramatically change patients’ sensitivity to and absorption of alcohol. Some…

Poop matters: Making the mouse gut microbiome more human-like

There is a growing consensus that the gut microbiome is involved in many aspects of physical and mental health, including the onset of Parkinson’s disease, multiple sclerosis, and even some behaviors. The microbiota of the small intestine in particular are…

Mass General Hospital researchers identify new ‘universal’ target for antiviral treatment

Mass General Hospital researchers identify new “universal” target for antiviral treatment BOSTON – As the coronavirus outbreak shows, viruses are a constant threat to humanity. Vaccines are regularly developed and deployed against specific viruses, but that process takes a lot…

Mass General Hospital researchers identify new ‘universal’ target for antiviral treatment

Mass General Hospital researchers identify new “universal” target for antiviral treatment BOSTON – As the coronavirus outbreak shows, viruses are a constant threat to humanity. Vaccines are regularly developed and deployed against specific viruses, but that process takes a lot…

Human Gut-in-a-Dish Model Helps Define ‘Leaky Gut,’ and Outline a Pathway to Treatment

UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.