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UrduPhysicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. The CSNP-based combination drug delivery therapy was proved to exert cholesterol-lowering,…
Tag: Cholesterol
Microbes might manage your cholesterol
Researchers discover mysterious bacteria that break down cholesterol in the gut
Dietary and physical activity intervention reduces LDL cholesterol level in children
An individualised and family-based physical activity and dietary intervention reduced the plasma LDL cholesterol concentration of primary school children, a new study from the University of Eastern Finland shows. The findings of the Physical Activity and Nutrition in Children (PANIC)…
Diabetes and metabolic syndrome
Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The…
Diabetes and metabolic syndrome
Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The…
Study identifies the mechanism by which eating fish reduces risk of cardiovascular disease
A diet rich in fish or omega 3 modulates the concentration of lipids that are passed on to cells by lipoproteins and reduces the likelihood of atherosclerosis, according to the most exhaustive study carried out to date by Universitat Rovira i Virgili and
Study identifies the mechanism by which eating fish reduces risk of cardiovascular disease
A diet rich in fish or omega 3 modulates the concentration of lipids that are passed on to cells by lipoproteins and reduces the likelihood of atherosclerosis, according to the most exhaustive study carried out to date by Universitat Rovira i Virgili and
Icosapent ethyl found to significantly reduce revascularizations in statin patients
WASHINGTON – Patients with high lipid levels have an increased risk for ischemic events, despite statin therapy. Findings presented as late-breaking science during the SCAI 2020 Scientific Sessions Virtual Conference revealed that for statin-treated patients with elevated triglycerides and increased…
Icosapent ethyl found to significantly reduce revascularizations in statin patients
WASHINGTON – Patients with high lipid levels have an increased risk for ischemic events, despite statin therapy. Findings presented as late-breaking science during the SCAI 2020 Scientific Sessions Virtual Conference revealed that for statin-treated patients with elevated triglycerides and increased…
How the body makes triglycerides
Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease. There is considerable interest in finding novel ways to effectively regulate triglycerides…
How the body makes triglycerides
Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease. There is considerable interest in finding novel ways to effectively regulate triglycerides…
Primary care case management among frequent users with chronic conditions
Case management in primary care for frequent users of health care services: A realist synthesis
Primary care case management among frequent users with chronic conditions
Case management in primary care for frequent users of health care services: A realist synthesis
New molecular auto-control system to avoid an excessive brown adipose tissue activity
Brown adipose tissue: how to auto-control its activity
New molecular auto-control system to avoid an excessive brown adipose tissue activity
Brown adipose tissue: how to auto-control its activity
Cholesterol lowering drugs linked to improved gut bacteria composition in obese people
The human gut microbiota consists of trillions of bacteria, fungi and virus constituting an inner chemical factory producing a multitude of microbial compounds affecting immunity, neurobiology and metabolism of the human host. It has for long been known that imbalances…
Cholesterol lowering drugs linked to improved gut bacteria composition in obese people
The human gut microbiota consists of trillions of bacteria, fungi and virus constituting an inner chemical factory producing a multitude of microbial compounds affecting immunity, neurobiology and metabolism of the human host. It has for long been known that imbalances…
Combining mouse and human data uncovers new gene regulating cholesterol
By combining the fine-grained detail available from animal studies with the statistical power of genetic studies involving hundreds of thousands of human genomes, researchers have discovered a new gene involved in regulating the body’s cholesterol.
Different kinds of white fat are important in disease
Multiple populations of subcutaneous white fat cells each may play different roles in obesity, diabetes and other diseases.
PCSK9 inhibitor with statin does not cause loss in memory, mental skills in high-risk patients
Two-year follow up of FOURIER study in 22,655 patients confirms neurocognitive safety of very low LDL-C levels using a patient self-survey tool
Lipid biomarkers key to cardiac repair differences in blacks and whites after heart attack
Study indicates that distinct lipid mediators may offer new targets for more personalized heart failure diagnosis and treatment
Different kinds of white fat are important in disease
Multiple populations of subcutaneous white fat cells each may play different roles in obesity, diabetes and other diseases.
Lipid biomarkers key to cardiac repair differences in blacks and whites after heart attack
Study indicates that distinct lipid mediators may offer new targets for more personalized heart failure diagnosis and treatment
PCSK9 inhibitor with statin does not cause loss in memory, mental skills in high-risk patients
Two-year follow up of FOURIER study in 22,655 patients confirms neurocognitive safety of very low LDL-C levels using a patient self-survey tool
‘Understanding Obesity: From its Causes to impact on Life’
Bentham has published the first volume in a new series of obesity references
‘Understanding Obesity: From its Causes to impact on Life’
Bentham has published the first volume in a new series of obesity references
Dietary counselling introduced in infancy leads to better cardiovascular health in adults
The Special Turku Coronary Risk Factor Intervention Project (STRIP) of the University of Turku, Finland, examines the benefits of promoting cardiovascular health by dietary counselling from infancy to early adulthood. Altogether 1,116 children and their families from Turku participated in…
Exercise during pregnancy reduces obesity among offspring
When physically fit women exercise during pregnancy they could be setting their children up for better fitness too. That’s according to a study published today in Science Advances led by Min Du, professor of animal sciences at Washington State University,…
A potential breakthrough in obesity medicine with the help of gold nanoparticles
A team of researchers in Korea believes to have discovered a synthetic gold-based compound which may help patients with obesity. The team led by Sunoh Kim, Deok-Chun Yang at Bioresources and Technology and Kyung Hee University, South Korea, respectively, investigated…
Larger thighs associated with lower risk of heart disease in obesity
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity, according to a study published in Endocrine Connections . In overweight and obese Chinese men and women, larger…
Composition of ‘Good’ Cholesterol HDL Varies in Different Organs
Article title: Organ-specific lymphatics play distinct roles in regulating HDL trafficking and composition Authors: Gracia Gracia, Enyuan Cao, Angus P. R. Johnston, Christopher J. H. Porter, Natalie L. Trevaskis From the authors: “The composition of lipoproteins, and in particular HDL, in lymph…
NIH-funded studies show stents and surgery no better than medication, lifestyle changes at reducing the risk for heart attack
NIH-funded studies find stents, surgery provide higher quality of life for those with chest pain
Alirocumab substantially reduces cholesterol in adult patients with HoFH
PCSK9 inhibitor evaluated for treating homozygous familial hypercholesterolemia
Evinacumab cuts cholesterol levels by half in patients with HoFH
Monoclonal antibody effective for the full spectrum of homozygous familial hypercholesterolemia
Removing belly fat before it sticks to you
University of Cincinnati researchers produce fat busting proteins in the laboratory
Novel blood test points to risk of weight gain and diabetes
The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted in Brazil with funding from FAPESP.
£500,000 NIHR grant for obesity treatment
Dr Jennifer Logue of Lancaster Medical School has been awarded half a million pounds by the National Institute for Health Research to examine the effectiveness of NHS and local government interventions to treat obesity. The three year project entitled “BEhavioural…
£500,000 NIHR grant for obesity treatment
Dr Jennifer Logue of Lancaster Medical School has been awarded half a million pounds by the National Institute for Health Research to examine the effectiveness of NHS and local government interventions to treat obesity. The three year project entitled “BEhavioural…
Molecule found in oranges could reduce obesity and prevent heart disease and diabetes
The equivalent of just two and a half glasses of orange juice a day could reverse obesity and reduce the risk of heart disease and diabetes. Researchers at Western University are studying a molecule found in sweet oranges and tangerines…
The world faces an air pollution ‘pandemic’
Researchers say people’s lives are shortened by an average of nearly three years from different sources of air pollution
The world faces an air pollution ‘pandemic’
Researchers say people’s lives are shortened by an average of nearly three years from different sources of air pollution
High sugar diet may impair metabolic health & maternal care after pregnancy
Rats on a high sugar diet during pregnancy have altered levels of sex steroid hormones (e.g. progesterone) and dopamine in their brains, which may lead to behavioural changes that can affect care of offspring and motivation, as well as increasing…
Sugary drinks a sour choice for adults trying to maintain normal cholesterol levels
Adults who drank sugary beverages daily had an increased risk of developing abnormal blood cholesterol and triglycerides compared to those who did not, according to new findings from a prospective study by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.
Metabolic health and weight management key to minimizing diabetes risk
New study based on Women’s Health Initiative data demonstrates significantly increased risk of diabetes in those who are metabolically unhealthy, even those of normal weight
Metabolic health and weight management key to minimizing diabetes risk
New study based on Women’s Health Initiative data demonstrates significantly increased risk of diabetes in those who are metabolically unhealthy, even those of normal weight
Study of 418,000 Europeans finds different foods linked to different types of stroke
Different types of food are linked to risks of different types of stroke, according to the largest study to investigate this, published in the European Heart Journal [1] today (Monday). Until now, most studies have looked at the association between…
Research reveals link between high cholesterol levels and risk of aortic valve disease
High cholesterol levels increase risk of developing aortic stenosis
Research reveals link between high cholesterol levels and risk of aortic valve disease
High cholesterol levels increase risk of developing aortic stenosis
Green tea extract combined with exercise reduces fatty liver disease in mice
Although untested in human trials, results suggest a potential health strategy
Green tea extract combined with exercise reduces fatty liver disease in mice
Although untested in human trials, results suggest a potential health strategy