Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet in Sweden shows that it is possible to eliminate the deleterious effects of…
Tag: Cholesterol
New study finds shared origins for individual chronic diseases in multimorbidity
A new study published today in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing not only one but multiple non-communicable diseases, which include cardiovascular disease, cancer, chronic respiratory disease and diabetes. The analysis of…
The benefits of the Mediterranean diet pass on to the families of patients who follow it
Despite not participating in the programme, these people had lost an average of almost four kilos, two years after their family member started the programme
Scientists Use Lipid Nanoparticles to Precisely Target Gene Editing to the Liver
Scientists developed a highly efficient, targeted method for delivering gene editing machinery to specific tissues and organs, demonstrating the treatment of high cholesterol by targeting genes in the liver of mice, reducing cholesterol for over 3 months (and potentially more) with one treatment
Not all “good” cholesterol is healthy
The work shows that people with large HDL particles have an increased risk of myocardial infarction, while only small HDL particles are actually associated with decreased risk
Many genes associated with the risk of coronary artery disease act through the liver
According to a new study published in The American Journal of Human Genetics , more than one third of genetic variants that increase the risk of coronary artery disease regulate the expression of genes in the liver. These variants have…
Association of maternal cardiovascular health during pregnancy with later health of offspring in adolescence
What The Study Did: The observational study examined associations between maternal cardiovascular health during pregnancy (as measured by body mass index, blood pressure, total cholesterol level, glucose level and smoking) with the later cardiovascular health of their offspring at ages 10…
Patient education program with mental health component reduces cardiovascular disease risks
CHAMPAIGN, Ill. — People who participated in a health education program that included both mental health and physical health information significantly reduced their risks of cardiovascular disease and other chronic diseases by the end of the 12-month intervention – and…
Vegan diet better for weight loss and cholesterol control than Mediterranean diet
A vegan diet is more effective for weight loss than a Mediterranean diet, according to a groundbreaking new study that compared the diets head to head. The randomized crossover trial, which was published in the Journal of the American College…
Probiotics or prebiotics? Exploring the complex world of ‘gut’ health
University of Missouri researchers develop a noninvasive way for identifying the major functions of the gastrointestinal tract.
New research looks at teen bariatric surgery outcomes by age
Results of study, published in Pediatrics, support early intervention based on clinical indication rather than age alone
New York Tech researchers secure NIH grant, study decalcification as heart disease therapy
A New York Institute of Technology research team led by Olga V. Savinova, Ph.D., assistant professor of biomedical sciences at New York Institute of Technology College of Osteopathic Medicine (NYITCOM), has secured a five-year grant from the National Institutes of…
Eating habits partly down to your genetics, finds new study
Your food intake patterns are partly under genetic control, according to the latest research from researchers at King’s College London, published today in the journal Twin Research and Human Genetics . Researchers can study the quality of an individual’s typical…
General health checkups may detect early signs of Parkinson’s disease
A research team led by Nagoya University in Japan has found that blood pressure, the hematocrit (the percentage of red blood cells in blood), and serum cholesterol levels change in patients with Parkinson’s disease long before the onset of motor…
Research shows impact of bariatric surgery on cardiovascular disease risk in obese teens
Five-year study by Children’s Hospital Colorado researchers published in Surgery for Obesity and Related Diseases
More years of obesity means higher risk of disease, study finds
A greater obesity duration is associated with worse values for all cardiometabolic disease factors, according to a new study published this week in PLOS Medicine by Tom Norris of Loughborough University, UK, and colleagues. People with obesity do not all…
A Novel Monoclonal Antibody Therapy Cuts LDL Cholesterol by Half in a High-Risk Patient Population, Study Shows
The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.
Being in treatment with statins reduces COVID-19 mortality by 22% to 25%
This drug is currently taken by one in four people to reduce cholesterol in the blood and thus prevent cardiovascular diseases
Muscle pain and energy-rich blood: Cholesterol medicine affects the organs differently
600,000 Danes take medicine containing statins. Statins lower the cholesterol level and thus helps prevent cardiovascular disease and blood clots. But there is a different side to the coin. Treatment with statins may also have negative side effects, some of…
Adults with endocrine disorders have an increased risk of heart disease
All adults with endocrine disorders should be tested for high cholesterol and triglycerides to evaluate their risk of heart attack or stroke, according to a Clinical Practice Guideline issued today by the Endocrine Society.
Cholesterol medications linked to lower cancer-related deaths in women
Among women with breast cancer, colorectal cancer, or melanoma, those who were taking cholesterol-lowering medications, were less likely to die from cancer, according to an analysis published in the British Journal of Clinical Pharmacology . The analysis included 20,046,11,719 and…
Obesity Medicine Association announces major updates to its Pediatric Obesity Algorithm
Updates help clinicians address chronic disease of obesity, identified as the most common cause of prevalent patient conditions
Weight loss surgery in obese diabetic patients significantly cuts pancreatic cancer risk
Weight loss surgery significantly cuts the risk of developing pancreatic cancer in people who are obese with diabetes, a new 20-year analysis has found
Testing for a lipoprotein linked to heart risk is as effective as blood work
Genetic risk scoring of lipoprotein(a) may have clinical utility in helping physicians identify candidates for treatment
Vigorous exercise, spongy heart
CNIC scientists have shown that vigorous physical exercise is linked to “noncompaction” of the heart, causing it to acquire a spongy appearance
Drink coffee after breakfast, not before, for better metabolic control
University of Bath press release
Neutrons reveal behavior of cholesterol in membranes
Neutron scattering at the Department of Energy’s Oak Ridge National Laboratory has shown that cholesterol stiffens simple lipid membranes, a finding that may help us better understand the functioning of human cells.
Gruthan Bioscience receives funding to develop a novel class of cholesterol-lowering drugs
Gruthan Bioscience was recently awarded funding to develop a novel class of cholesterol-lowering drugs to treat a rare form of familial hypercholesterolemia; It could one day be used to treat high cholesterol more widely
Having high cholesterol levels early in life leads to heart problems by middle age
Finding could lead to more aggressive strategies to lower cholesterol in early adulthood
Could breadfruit be the next superfood? UBC researchers say yes
Breadfruit is sustainable, environmentally friendly and a high-production crop
New genetic analysis method could advance personal genomics
Computational method capable of decoding influence of rare variants
Cholesterol drug combinations could cut health risk for European patients
New findings from a large European study of patients in 18 countries, including the UK, show that while many patients are able to reduce their risk through taking statins, those at the highest risk of cardiovascular events may benefit from…
‘Selfies’ could be used to detect heart disease
Sending a “selfie” to the doctor could be a cheap and simple way of detecting heart disease, according to the authors of a new study published today (Friday) in the European Heart Journal
‘Selfies’ could be used to detect heart disease
New research uses artificial intelligence to analyse facial photos
Genetic background influences disease risk from single-gene variants
In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk
Low ‘good’ cholesterol levels found in Latin America and the Caribbean
New findings suggest low levels of HDL cholesterol are the most common kind of lipid disorder in Latin America and the Caribbean
Autism-cholesterol link
New research reveals a subtype of autism associated with lipid abnormalities
This online calculator can predict your stroke risk, study finds
Doctors can predict patients’ risk for ischemic stroke based on the severity of their metabolic syndrome, a conglomeration of conditions that includes high blood pressure, abnormal cholesterol levels and excess body fat around the abdomen and waist, a new study…
Food-based approach to lowering cholesterol provides significant healthcare cost savings
Findings support offering insurance-based incentives for clinically proven diet-based lipid lowering interventions such as Step One Foods
Fireflies shed light on the function of mitochondria
Thanks to a bioluminescent molecule, scientists at EPFL can observe mitochondria at work in living mammals
Scientists discover the switch that makes human brown fat burn energy
An international research team have discovered how to activate brown fat in humans, which may lead to new treatments for type 2 diabetes and obesity. The results of the collaboration between the Centre de recherche du Centre hospitalier universitaire de…
ACC issues updated guidance on cardiovascular risk reduction in type 2 diabetes patients
New expert consensus decision pathway incorporates emerging study data on novel diabetes therapies
Cholesterol-Lowering Drug Improved Function of Heart’s Arteries
In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.
Better Measure of ‘Good Cholesterol’ Can Gauge Heart Attack And Stroke Risk in Some Populations
DALLAS – June 22, 2020 – For decades, high-density lipoprotein (HDL) cholesterol has been dubbed “good cholesterol” because of its role in moving fats and other cholesterol molecules out of artery walls. People with higher HDL cholesterol levels tend to have lower rates of cardiovascular disease, studies have shown.
T cells can shift from helping to harming in atherosclerosis
At La Jolla Institute for Immunology (LJI) researchers are dedicated to finding a way to stop plaques from forming in the first place. In a new study, LJI scientists show that certain T lymphocytes, a type of white blood cell, that start out trying to fight the disease can end up increasing inflammation and making atherosclerosis cases even worse.
Plant-based diets high in carbs improve type 1 diabetes, according to new case studies
Studies challenge misconception that carbs are bad for diabetes
Should nursing home residents nearing the end of life continue taking statins?
Journal of the American Geriatrics Society Research Summary
Should nursing home residents nearing the end of life continue taking statins?
Journal of the American Geriatrics Society Research Summary
New nanoparticle drug combination for atherosclerosis
Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. The CSNP-based combination drug delivery therapy was proved to exert cholesterol-lowering,…
Microbes might manage your cholesterol
Researchers discover mysterious bacteria that break down cholesterol in the gut