Metabolic derangements caused by a high-fat diet may be possible to eliminate

Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet in Sweden shows that it is possible to eliminate the deleterious effects of…

New study finds shared origins for individual chronic diseases in multimorbidity

A new study published today in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing not only one but multiple non-communicable diseases, which include cardiovascular disease, cancer, chronic respiratory disease and diabetes. The analysis of…

Association of maternal cardiovascular health during pregnancy with later health of offspring in adolescence

What The Study Did: The observational study examined associations between maternal cardiovascular health during pregnancy (as measured by body mass index, blood pressure, total cholesterol level, glucose level and smoking) with the later cardiovascular health of their offspring at ages 10…

Patient education program with mental health component reduces cardiovascular disease risks

CHAMPAIGN, Ill. — People who participated in a health education program that included both mental health and physical health information significantly reduced their risks of cardiovascular disease and other chronic diseases by the end of the 12-month intervention – and…

Vegan diet better for weight loss and cholesterol control than Mediterranean diet

A vegan diet is more effective for weight loss than a Mediterranean diet, according to a groundbreaking new study that compared the diets head to head. The randomized crossover trial, which was published in the Journal of the American College…

More years of obesity means higher risk of disease, study finds

A greater obesity duration is associated with worse values for all cardiometabolic disease factors, according to a new study published this week in PLOS Medicine by Tom Norris of Loughborough University, UK, and colleagues. People with obesity do not all…

A Novel Monoclonal Antibody Therapy Cuts LDL Cholesterol by Half in a High-Risk Patient Population, Study Shows

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

Muscle pain and energy-rich blood: Cholesterol medicine affects the organs differently

600,000 Danes take medicine containing statins. Statins lower the cholesterol level and thus helps prevent cardiovascular disease and blood clots. But there is a different side to the coin. Treatment with statins may also have negative side effects, some of…

Cholesterol medications linked to lower cancer-related deaths in women

Among women with breast cancer, colorectal cancer, or melanoma, those who were taking cholesterol-lowering medications, were less likely to die from cancer, according to an analysis published in the British Journal of Clinical Pharmacology . The analysis included 20,046,11,719 and…

Gruthan Bioscience receives funding to develop a novel class of cholesterol-lowering drugs

Gruthan Bioscience was recently awarded funding to develop a novel class of cholesterol-lowering drugs to treat a rare form of familial hypercholesterolemia; It could one day be used to treat high cholesterol more widely

This online calculator can predict your stroke risk, study finds

Doctors can predict patients’ risk for ischemic stroke based on the severity of their metabolic syndrome, a conglomeration of conditions that includes high blood pressure, abnormal cholesterol levels and excess body fat around the abdomen and waist, a new study…

Cholesterol-Lowering Drug Improved Function of Heart’s Arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

Better Measure of ‘Good Cholesterol’ Can Gauge Heart Attack And Stroke Risk in Some Populations

DALLAS – June 22, 2020 – For decades, high-density lipoprotein (HDL) cholesterol has been dubbed “good cholesterol” because of its role in moving fats and other cholesterol molecules out of artery walls. People with higher HDL cholesterol levels tend to have lower rates of cardiovascular disease, studies have shown.

T cells can shift from helping to harming in atherosclerosis

At La Jolla Institute for Immunology (LJI) researchers are dedicated to finding a way to stop plaques from forming in the first place. In a new study, LJI scientists show that certain T lymphocytes, a type of white blood cell, that start out trying to fight the disease can end up increasing inflammation and making atherosclerosis cases even worse.

New nanoparticle drug combination for atherosclerosis

Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. The CSNP-based combination drug delivery therapy was proved to exert cholesterol-lowering,…