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UrduHeidelberg, 25 November 2019 – EMBO Press is pleased to announce the appointment of systems biologist M. Madan Babu as the new Chief Editor of Molecular Systems Biology . Madan Babu, who heads the regulatory genomics and systems biology group…
Tag: Bioinformatics
Molecular Systems Biology appoints M. Madan Babu as new Chief Editor
Heidelberg, 25 November 2019 – EMBO Press is pleased to announce the appointment of systems biologist M. Madan Babu as the new Chief Editor of Molecular Systems Biology . Madan Babu, who heads the regulatory genomics and systems biology group…
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people. It involves large quantities of malignant progenitor cells building up in a person’s blood instead of healthy white blood cells. This is often…
Predicting metastasis from primary tumor size
New mathematical model calculates chances that undetectable metastases are present
Simple model explains why different four-legged animals adopt similar gaits
Most mammals walk at slow speeds and run or trot at intermediate speeds because these movement strategies are energetically optimal, according to a study published in PLOS Computational Biology by Delyle Polet and John Bertram of the University of Calgary…
How do gliomas evolve?
The Glioma Longitudinal Analysis (GLASS) Consortium finds longitudinal molecular trajectories of diffuse glioma in adults
3D maps of gene activity
Professor Nikolaus Rajewsky is a visionary: He wants to understand exactly what happens in human cells during disease progression, with the goal of being able to recognize and treat the very first cellular changes. “This requires us not only to…
Researchers develop new database of druggable fusion targets
When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play a vital…
Children’s Tumor Foundation and DELopen increase access to compounds for neurofibromatosis
New York: November 19, 2019 – The Children’s Tumor Foundation (CTF), an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D…
Malaria discovery could lead to better HIV and lupus treatments
A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus, say Australian researchers. The research team showed, in laboratory models, that strong inflammatory signals caused by malaria infection…
Children’s Tumor Foundation and DELopen increase access to compounds for neurofibromatosis
New York: November 19, 2019 – The Children’s Tumor Foundation (CTF), an innovative and global neurofibromatosis (NF) research foundation announced today a collaboration with DELopen, a DNA-encoded library technology platform sponsored by WuXi AppTec, a leading global provider of R&D…
Malaria discovery could lead to better HIV and lupus treatments
A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus, say Australian researchers. The research team showed, in laboratory models, that strong inflammatory signals caused by malaria infection…
Antibiotics from the sea
International research team taps potential source of new antibiotics
Genetic alterations caused by cancer therapies identified
Living implies change. This is what happens to the cells of our bodies as we grow older: they accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain genes and can lead…
Antibiotics from the sea
International research team taps potential source of new antibiotics
Genetic alterations caused by cancer therapies identified
Living implies change. This is what happens to the cells of our bodies as we grow older: they accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain genes and can lead…
Metabolic syndrome: New use for an old drug
The syndrome, which affects more than 35% of the over-50 population in Western countries, could be treated with Ibrutinib, a drug that has already been approved for other diseases
Lichens are way younger than scientists thought
You’ve probably seen a lichen, even if you didn’t realize it. If you’ve ever meandered through the forest and wondered what the crusty stuff on trees or rocks was, they’re lichens, a combination of algae and fungi living together almost…
Genetic Variation in Individual Brain Cell Types May Predict Disease Risk
Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.
TGen-USC researchers link sisters’ paralysis to an ‘extremely rare’ genetic variant
Diagnosis by TGen’s Center for Rare Childhood Disorders gives solace to parents who searched a quarter-century for answers
TGen-USC researchers link sisters’ paralysis to an ‘extremely rare’ genetic variant
Diagnosis by TGen’s Center for Rare Childhood Disorders gives solace to parents who searched a quarter-century for answers
Artificial Intelligence Tool Predicts Life Expectancy in Heart Failure Patients
Researchers at University of California San Diego School of Medicine, as well as a diverse team of cardiologists and physicists, developed a machine learning algorithm to predict the life expectancy in heart failure patients.
Chitin-binding proteins override host plant’s resistance to fungal infection
An insoluble complex carbohydrate, chitin makes up fungal walls and plays a significant role in the interaction between fungal pathogens and their plant hosts. Plant cells harbor immune receptors that perceive chitin and work to stop fungal infection. However, fungal…
Predicting evolution
What survives, thrives and dominates over a thousand generations? The answer might be even more complex than previously thought
Chitin-binding proteins override host plant’s resistance to fungal infection
An insoluble complex carbohydrate, chitin makes up fungal walls and plays a significant role in the interaction between fungal pathogens and their plant hosts. Plant cells harbor immune receptors that perceive chitin and work to stop fungal infection. However, fungal…
Predicting evolution
What survives, thrives and dominates over a thousand generations? The answer might be even more complex than previously thought
Widespread misinterpretation of gene expression data
Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified. RNA-seq, one of the most widely used methods in modern molecular biology, allows in a single…
Widespread misinterpretation of gene expression data
Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified. RNA-seq, one of the most widely used methods in modern molecular biology, allows in a single…
Hot town, springtime in the city: Urbanization delays spring plant growth in warm regions
GAINESVILLE, Fla. — The first appearance of bright green leaves heralds the start of spring, nudging insects, birds and other animals into a whirlwind of action. But a new study shows that urbanization shifts this seasonal cue in nuanced ways,…
New symposium highlights research on targeting of incurable diseases via RNA
Titled: ‘RNA – From Biology to Drug Discovery,’ day-long conference to focus on translational promise of a novel targeting strategy
For the first time: A method for measuring animal personality
A study on mice shows animal research may need to take into account the connection between genes, behavior and personality
Hot town, springtime in the city: Urbanization delays spring plant growth in warm regions
GAINESVILLE, Fla. — The first appearance of bright green leaves heralds the start of spring, nudging insects, birds and other animals into a whirlwind of action. But a new study shows that urbanization shifts this seasonal cue in nuanced ways,…
New symposium highlights research on targeting of incurable diseases via RNA
Titled: ‘RNA – From Biology to Drug Discovery,’ day-long conference to focus on translational promise of a novel targeting strategy
For the first time: A method for measuring animal personality
A study on mice shows animal research may need to take into account the connection between genes, behavior and personality
New tool facilitates genetic mapping of polyploid plants
Available online for free, polyploid mapping system developed in Brazil helps breeders of sugarcane, kiwi, blueberry, sweet potato and forages, among other crops
Integrating imaging research across Europe
Euro-BioImaging established as a European Research Infrastructure Consortium for state-of-the-art imaging services in biological and biomedical research
The way of making memories
New study on how memories are formed and the ability of the nervous system to learn and adapt to changing conditions
Introducing GMpi: Affordable and adaptable remote monitoring for plant growth experiments
Growth chambers are a cornerstone of laboratory-based plant science, allowing for the tightly controlled conditions necessary for many experimental designs. However, these conditions can sometimes be a little less than controlled, creating headaches ranging from reproducibility issues to the loss…
A new CRISPR-Cas9 protein to increase precision of gene editing
A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful…
A new machine learning approach detects esophageal cancer better than current methods
Researchers at Dartmouth’s Norris Cotton Cancer Center have created a deep learning model that can accurately identify cancerous esophagus tissue on microscopy images without the time-consuming manual data input required for current methods
Solution of the high-resolution crystal structure of stress proteins from Staphylococcus
A paper was published by Kazan Federal University in the Journal of Structural Biology
Neuron circuitry from brain signals
Using machine learning to construct a map of neuronal connections
NJIT professor wins Fulbright Award, joins international circadian clock research project
Casey Diekman, associate professor of mathematics at New Jersey Institute of Technology (NJIT), has been named recipient of a prestigious Fulbright U.S. Scholar Program Award to the United Kingdom in Mathematical Biology. With the announcement of his Fulbright U.S. Scholar…
A new CRISPR-Cas9 protein to increase precision of gene editing
A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful…
A new machine learning approach detects esophageal cancer better than current methods
Researchers at Dartmouth’s Norris Cotton Cancer Center have created a deep learning model that can accurately identify cancerous esophagus tissue on microscopy images without the time-consuming manual data input required for current methods
Solution of the high-resolution crystal structure of stress proteins from Staphylococcus
A paper was published by Kazan Federal University in the Journal of Structural Biology
Neuron circuitry from brain signals
Using machine learning to construct a map of neuronal connections
NJIT professor wins Fulbright Award, joins international circadian clock research project
Casey Diekman, associate professor of mathematics at New Jersey Institute of Technology (NJIT), has been named recipient of a prestigious Fulbright U.S. Scholar Program Award to the United Kingdom in Mathematical Biology. With the announcement of his Fulbright U.S. Scholar…
New mechanism for development of type 1 diabetes implicates more active role for ß cells
-Exposure of pancreatic islets cells to inflammatory cytokines results in the activation of non-coding DNA regions that act as “switches” to trigger gene expression and protein translation. This study has mapped these non-coding regions in islet cells. -Genetic variants that…