In a significant advance against the growing threat of antibiotic-resistant bacteria, , researchers have identified a novel class of antimicrobial agents known as encrypted peptides, which may expand the immune system’s arsenal of tools to fight infection.
Tag: Peptides
Largest-ever antibiotic discovery effort uses AI to uncover potential cures in microbial dark matter
Almost a century ago, the discovery of antibiotics like penicillin revolutionized medicine by harnessing the natural bacteria-killing abilities of microbes. Today, a new study co-led by researchers at the Perelman School of Medicine at the University of Pennsylvania suggests that natural-product antibiotic discovery is about to accelerate into a new era, powered by artificial intelligence (AI).
Study opens new avenue for immunotherapy drug development
In a new study published today in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the body.
The gold standard: Nobel Prize gifted to Tulane University by Dr. Andrew Schally
Former Tulane University researcher Dr. Andrew Schally has donated his Nobel Prize to Tulane’s School of Medicine. Schally won the award in 1977 for identifying the presence of key peptides in the hypothalamus and successfully synthesizing them, research that led to advanced prostate cancer treatment methods.
How drugs get into the blood
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, especially those that can penetrate cell membranes, as these are the only ones that patients can take orally in the form of a tablet or syrup.
Tracing the origin of life
The origin of life is one of the great questions of mankind. One of the prerequisites for the emergence of life is the abiotic – not by living beings caused chemical – production and polymerization of amino acids, the building blocks of life.
New molecular blocker halts breast cancer metastasis
Cancer cells use feet-like protrusions called invadopodia to degrade underlying tissue, enter the bloodstream and form metastases in other organs.
Researchers discover unique peptides with anti-cancer potential
A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.
Danforth Technology Company launches its first startup: PEPTYDE BIO
Peptyde Bio discovers, designs, and characterizes novel anti-microbial peptides (AMPs)
Human cells take in less protein from a plant-based meat than from chicken
In ACS’ Journal of Agricultural and Food Chemistry, researchers report that proteins in a model plant-based substitute were not as accessible to cells as those from meat. The team says this knowledge could eventually be used to develop more healthful products.
Nasal Drugs Show Promise for Slowing Parkinson’s Disease Progression in Lab Study
Rush researchers have shown that two lab-developed and nasally-delivered peptides helped slow the spread of alpha-synuclein in mice.
How migraines protect against diabetes
People who get migraines are less likely to develop type 2 diabetes. Today, scientists report the latest findings about the relationship between insulin production and the peptides that cause migraine pain. They will present their results at ACS Fall 2021.
What if We Could Give Viruses a One-Two Punch?
Researchers at Stanford and Berkeley Lab’s Molecular Foundry have developed virus-killing molecules called peptoids. The technology could make possible an emerging category of antiviral drugs that could treat everything from herpes and COVID-19 to the common cold.
Designer Polymers Created from Peptide Bundles Promise Super-Strong Future Materials
New computer design methods pave the way for scientists to design and assemble bundles of peptides with specific size, shape, and display characteristics. Scientists can then link these customizable building blocks, called bundlemers, to produce a huge array of polymers.