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UrduThe approach, with ,no side effects, was to treat obesity as an inflammatory disease
Tag: METABOLISM/METABOLIC DISEASES
Adam Guenzel, PhD is the recipient of the 2021 Richard King Trainee Award
Adam Guenzel, PhD receives the 2021 Richard King Award for Best Publication by a Trainee in Genetics in Medicine
Novel diabetes subgroups show differences in biomarkers of inflammation
Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future? Symptoms that increase with age, such as cardiovascular disease,…
Closer to human — Mouse model more accurately reproduces fatty liver disease
Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant. “NAFLD has been difficult to study mainly because we had no good animal model,”…
Family ties: Early cardiac events pose major and different risks in close relatives
Family history of early cardiac events in first degree relatives such as a parent or sibling is a major risk factor, especially for premature events. Currently, data on risks in close relatives of patients with a family history of premature…
Schedule announced for NUTRITION 2021 LIVE ONLINE
Press passes now available for the year’s biggest virtual nutrition meeting
Leptin puts the brakes on eating via novel neurocircuit
Energy balance includes modulation of dopamine reward signaling
New perspective to understand and treat a rare calcification disease
Researchers developed a new animal model to study a rare genetic disease that can lead to blindness at the age of 40-50.
The first non-invasive biomarker to track and verify efficacy of senolytic drugs
The discovery and development of a lipid-metabolite biomarker is expected to facilitate research and clinical trials of drugs that target multiple age-related diseases
HKBU-led research reveals hyocholic acids are promising agents for diabetes prediction and treatment
A series of studies led by researchers from Hong Kong Baptist University (HKBU) have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of…
UArizona Health Sciences study will develop first population-based dietary mobile app
A $3.3 million NIH grant is funding a five-year UArizona Health Sciences study designed to develop a mobile assessment tool to more accurately, and in near real-time, track and measure saturated fat and added sugar consumption.
New approach for the development of a drug treatment for obesity and the resulting diseases
The protein Asc-1 regulates whether fat-burning beige or fat-storing white adipocytes are formed, which can have an impact on the development of metabolic diseases. This is shown by a current study of the Helmholtz Zentrum München and the German Center…
Sugar not so nice for your child’s brain development
New research shows how high consumption affects learning, memory
Fasting acts as diet catalyst
One in four Germans suffers from metabolic syndrome. Several of four diseases of affluence occur at the same time in this ‘deadly quartet’: obesity, high blood pressure, lipid metabolism disorder and diabetes mellitus. Each of these is a risk factor…
Kids’ metabolic health can be improved with exercise during pregnancy: here’s why
BOSTON – (March 25, 2021) – A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring. According to researchers, the key lies with a protein called SOD3, vitamin D and adequate exercise,…
Bespoke neuroblastoma therapy weaponizes cell metabolism
New mouse study shows that combining a new drug with an old one could exploit the insatiable “hunger” of a deadly childhood cancer
GlyNAC improves multiple defects in aging to boost strength and cognition in older humans
A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione – could improve many age-associated defects in older…
TGen-ASU review suggests added sugars are contributing to liver disease among children
Reduction in global consumption of added fructose would yield a positive impact
Vitamin D deficiency linked to metabolic changes in patients with lupus – study
Patients with lupus are more likely to have metabolic syndrome and insulin resistance – both factors linked to heart disease – if they have lower vitamin D levels, a new study reveals. Researchers believe that boosting vitamin D levels may…
Circadian clock gene Rev-erb linked to dawn phenomenon in type 2 diabetes
Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn phenomenon, an abnormal increase of blood sugar only in the morning, observed in many patients with type 2 diabetes. They…
Cholesterol may be key to new therapies for Alzheimer’s disease, diabetes
A unique approach to tackling these two diseases has allowed Dr. Gregory Thatcher to look beyond traditional causes to find novel therapies
IFCC-IOF study investigates harmonization of assays for ß-CTX
New study by the IFCC-IOF Committee for Bone Metabolism shows large within- & between-assay variation for ß-CTX measurement; until harmonization is achieved, proposes measuring ß-CTX by the same assay on EDTA plasma, especially for research
Physical activity helps curb low-grade inflammation in children
Low physical activity, unhealthy diet quality, and being overweight is the most unfavourable combination
Ultra-processed foods are breaking your heart
Ultra-processed food consumption associated with increased risk of heart disease, death
Aging-US: Aging and rejuvenation – a modular epigenome model
This www.Aging-US.com study reports that epigenetic rejuvenation seems to hold the key to arresting or even reversing organismal aging
UMass Amherst researchers develop ultra-sensitive flow microsensors
Research could lead to more breakthroughs in neuroscience, metabolism
Readmission rate high for adults hospitalized for diabetic ketoacidosis
Readmitted patients with type 1 diabetes have two times the death rate during second hospitalization
Children, teens with type 1 diabetes had better glucose control during COVID-19 lockdown
Study highlights challenges of managing disease with activities outside the home
Genetic evidence suggests men can develop PCOS-like condition
Study indicates PCOS may not be primarily a female reproductive disorder
Night owls with gestational diabetes may face higher risk of pregnancy complications
Mothers who prefer evening activity also more likely to give birth to newborns requiring neonatal intensive care
Semaglutide reduces excess body fat in people with obesity
Findings suggest drug has potential to reduce risk of heart disease, diabetes and stroke
Study examines fermented milks’ potential benefits for decreasing high blood pressure through modulation of gut microbiota
Potential for the development of tailor-made fermented milks to help reduce hypertension, according to the Journal of Dairy Science
Dieting suppresses ‘cellular engines’, weight loss surgery gives boost to mitochondria
Dieting impairs the energy-producing machinery of fat tissue, potentially resulting in weight regain
Double duty: Gut’s immune system helps regulate food processing, too
The small intestine is ground zero for survival of animals. It is responsible for absorbing the nutrients crucial to life and it wards off toxic chemicals and life-threatening bacteria. In a new study published March 18 in the journal Science…
Scientist gets $2 million grant to study how inflammation, gut microbiota promote metabolic syndrome
ATLANTA–Dr. Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year federal grant just over $2 million to study how inflammation and altered gut microbiota, the microorganisms living in the intestine, influence…
Consumption of added sugar doubles fat production
Sugar is added to many common foodstuffs, and people in Switzerland consume more than 100 grams of it every day. The high calorie content of sugar causes excessive weight and obesity, and the associated diseases. But does too much sugar…
HIV research: Increased weight gain with TAF medication
In Switzerland about 17 000 people are living with an HIV infection, worldwide there are about 38 million. Today, the disease can be treated so successfully that a normal life can be ensured to a great extent. However, weight increases…
Insulin rises before cells develop resistance, new diabetes research implies
Researchers at the University of Gothenburg, Sweden, have now presented results that may change our basic view of how type 2 diabetes occurs. Their study indicates that free fatty acids (FFAs) in the blood trigger insulin release even at a…
Exercise during pregnancy may save kids from health problems as adults
Parental obesity predisposes children to develop diabetes, metabolic issues
Multiyear workplace health promotion program shown to prevent health risks
The results of an eight-year workplace health promotion program were encouraging for health promotion
An unusual creature is coming out of winter’s slumber. Here’s why scientists are excited.
Duke Lemur Center recreates the seasonal swings of native habitat, helping to unlock the secrets of hibernation.
Metabolic derangements caused by a high-fat diet may be possible to eliminate
Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet in Sweden shows that it is possible to eliminate the deleterious effects of…
New study finds shared origins for individual chronic diseases in multimorbidity
A new study published today in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing not only one but multiple non-communicable diseases, which include cardiovascular disease, cancer, chronic respiratory disease and diabetes. The analysis of…
Trial compares two gestational diabetes screening methods
Kaiser Permanente researchers conducted a large-scale randomized trial involving nearly 24,000 women and found no difference in health outcomes.
The benefits of the Mediterranean diet pass on to the families of patients who follow it
Despite not participating in the programme, these people had lost an average of almost four kilos, two years after their family member started the programme
Health behavior outcomes can help determine efficacy of interventions for multimorbidities
Scaling up patient-centered interdisciplinary care for multimorbidity: A pragmatic mixed-methods randomized controlled trial
March/April 2021 Annals of Family Medicine Tip Sheet
Study Reveals New Hope for Men With Common Urinary Issues A new systematic review of evidence recommends the use of behavioral self-management treatments for common urinary issues experienced by upwards of 70 percent of older men. Common symptoms include trouble…
Use of patient data guides outreach to treat and monitor people with diabetes
Strategies and factors associated with top performance in primary care for diabetes: Insights from a mixed methods study
Women with polycystic ovary syndrome at significantly increased risk of COVID-19
Women with polycystic ovary syndrome (PCOS) are at a significantly increased risk of contracting COVID-19 than women without the condition, new research led by the University of Birmingham has revealed. Researchers are now calling for healthcare policy to specifically encourage…
Hospital admissions associated with noncommunicable diseases during COVID-19 outbreak in Brazil
What The Study Did: Researchers assessed the number of hospital admissions for noncommunicable diseases (abnormal tissue growths, metabolic diseases, cardiovascular diseases and musculoskeletal diseases) in São Paulo, Brazil, between January and June last year compared with the corresponding periods in the…