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UrduNew research reveals a subtype of autism associated with lipid abnormalities
Tag: METABOLISM/METABOLIC DISEASES
This online calculator can predict your stroke risk, study finds
Doctors can predict patients’ risk for ischemic stroke based on the severity of their metabolic syndrome, a conglomeration of conditions that includes high blood pressure, abnormal cholesterol levels and excess body fat around the abdomen and waist, a new study…
Food-based approach to lowering cholesterol provides significant healthcare cost savings
Findings support offering insurance-based incentives for clinically proven diet-based lipid lowering interventions such as Step One Foods
Waistline matters in kidney disease
Obesity as assessed by body mass index is associated with an increased risk of heart disease and progression of kidney disease in those with chronic kidney disease (CKD). In this cohort of patients with CKD, Sankar D. Navaneethan et al…
Flipping a metabolic switch to slow tumor growth
The enzyme serine palmitoyl-transferase can be used as a metabolically responsive “switch” that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature . By…
Lack of females in drug dose trials leads to overmedicated women
Gender gap leaves women experiencing adverse drug reactions nearly twice as often as men, study shows
Fireflies shed light on the function of mitochondria
Thanks to a bioluminescent molecule, scientists at EPFL can observe mitochondria at work in living mammals
TB vaccine research could benefit the elderly and diabetics
A study of older mice with type 2 diabetes has yielded highly promising results for researchers investigating potential new vaccines for tuberculosis (TB). A team of researchers from Australia, Bangladesh and France investigated a potential vaccine, BCG::RD1, and found it…
NSD2 enzyme appears to prevent cellular senescence
Toward an era where aging can be controlled
New test better predicts which babies will develop type 1 diabetes
A new approach to predicting which babies will develop type 1 diabetes moves a step closer to routine testing for newborns which could avoid life-threatening complications. Scientists at seven international sites have followed 7,798 children at high risk of developing…
Antibiotics linked to higher heart disease risk in individuals with type 1 diabetes
Results from a study published in the Journal of Internal Medicine suggest that bacterial infections may elevate the risk of coronary heart disease in individuals with type 1 diabetes. Among 3,781 individuals with type 1 diabetes, 370 developed coronary heart…
Rheumatoid arthritis linked to a lower risk of type 2 diabetes
A recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other individuals, including those with other types of arthritis. The analysis, which is published in…
Scientists discover the switch that makes human brown fat burn energy
An international research team have discovered how to activate brown fat in humans, which may lead to new treatments for type 2 diabetes and obesity. The results of the collaboration between the Centre de recherche du Centre hospitalier universitaire de…
New strategy against osteoporosis
Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women and one in five men aged over 50 suffer from osteoporotic bone fractures. Osteoporosis is caused…
Altered lipid metabolism following childbirth predicts later diabetes risk
Measuring postpartum changes in lipid metabolism in women who had gestational diabetes may identify those at risk of developing type 2 diabetes and enable them to receive preventive care
New molecule reverses Alzheimer’s-like memory decline
Salk study demonstrates that the drug CMS121 treats neurodegeneration in mice
New obesity guideline: Address root causes as foundation of obesity management
Move away from stigma
NTU and A*STAR scientists develop new way to deliver more drugs through the skin
Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR) have showed that applying “temporal pressure” to the skin of mice can create a new way to deliver drugs. In a paper published…
Canakinumab shows promise for treatment of large joint osteoarthritis
Embargoed news from Annals of Internal Medicine
Youth more likely to stick with CGM if they are part of decision to start
New study by CHOP researchers finds having youth buy-in from the beginning helps ensure consistent use of continuous glucose monitoring
Gene variations at birth reveal origins of inflammation and immune disease
A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis…
Comprehensive study of vaccine safety concludes that vaccines are ‘remarkably safe’
Embargoed News from Annals of Internal Medicine
Researchers develop a portable blood ammonia detector
Seated around the dinner table, faculty affiliated with Stanford ChEM-H – one of Stanford University’s interdisciplinary institutes – spoke one-by-one, pitching ideas for collaborative research. Inspired by a recent medical conundrum, Gilbert Chu, a professor of medicine (oncology) and of…
Researchers develop a portable blood ammonia detector
Seated around the dinner table, faculty affiliated with Stanford ChEM-H – one of Stanford University’s interdisciplinary institutes – spoke one-by-one, pitching ideas for collaborative research. Inspired by a recent medical conundrum, Gilbert Chu, a professor of medicine (oncology) and of…
Dietary guidelines advisory committee reinforces need for increased choline intake
Vulnerable populations, including infants, toddlers, pregnant and lactating women, are at greatest risk for choline deficiency
City of Hope: Mechanism that may lead to metabolic memory/sustained diabetes complications
New data show how early episodes of hyperglycemia can have long-term effects
Gut microbiota provide clues for treating diabetes
The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated.
Oat and rye bran fibres alter gut microbiota, reducing weight gain and hepatic inflammation
In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.
Gas cooker exposure can lower blood pressure, study finds
The study, published recently in Circulation Research and led by a team from King’s College London, has investigated how nitrogen dioxide can impact the cardiovascular system. The study examined the blood chemistry and cardiovascular changes of 12 healthy volunteers. They…
Promising treatment to slow kidney disease doesn’t prove out in clinical trial
Scientists find that reducing levels of uric acid in the blood does not guard against complication in type 1 diabetes.
Maternal obesity increases the chance of liver cancer in offspring for generations
Scientists have identified a microRNA in obese mouse mothers that may increase the odds of liver cancer in their offspring throughout multiple generations, report scientists in the Journal of Hepatology
Promising treatment to slow kidney disease doesn’t prove out in clinical trial
Scientists find that reducing levels of uric acid in the blood does not guard against complication in type 1 diabetes.
Maternal obesity increases the chance of liver cancer in offspring for generations
Scientists have identified a microRNA in obese mouse mothers that may increase the odds of liver cancer in their offspring throughout multiple generations, report scientists in the Journal of Hepatology
Childhood obesity linked to multiple environmental factors in first-of-its-kind study
Exposure to smoking and air pollution as well as living in densely populated areas or those with low walkability pinpointed by international collaboration co-led by Keck School of Medicine of USC
CNIC scientists identify the mechanism that regulates mitochondrial energy production
The regulatory protein SCAF1 enables mitochondria to adapt to the available nutrient source of sugars, fats, or proteins
‘Stay at home but don’t stay still,’ researchers recommend
In a review article published in the American Journal of Physiology, Brazilian researchers present scientific evidence on the impact of short periods of inactivity on the cardiovascular system and recommend exercise to stay fit at home during the pandemic
Childhood obesity linked to multiple environmental factors in first-of-its-kind study
Exposure to smoking and air pollution as well as living in densely populated areas or those with low walkability pinpointed by international collaboration co-led by Keck School of Medicine of USC
CNIC scientists identify the mechanism that regulates mitochondrial energy production
The regulatory protein SCAF1 enables mitochondria to adapt to the available nutrient source of sugars, fats, or proteins
‘Stay at home but don’t stay still,’ researchers recommend
In a review article published in the American Journal of Physiology, Brazilian researchers present scientific evidence on the impact of short periods of inactivity on the cardiovascular system and recommend exercise to stay fit at home during the pandemic
Females use anti-inflammatory T cells to keep their blood pressure down
In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say. Females…
Statement on metabolic and bariatric surgery during COVID-19 pandemic
American Society for Metabolic and Bariatric Surgery (ASMBS) calls for safe resumption of bariatric and metabolic surgery before COVID-19 pandemic is declared over
Females use anti-inflammatory T cells to keep their blood pressure down
In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say. Females…
Statement on metabolic and bariatric surgery during COVID-19 pandemic
American Society for Metabolic and Bariatric Surgery (ASMBS) calls for safe resumption of bariatric and metabolic surgery before COVID-19 pandemic is declared over
Unique metabolic markers detect over 50% of children affected by autism spectrum disorder
New findings from the Children’s Autism Metabolome Project (CAMP) Study, a 1,102 subject study of the metabolism of children with ASD, published in Autism Research
Why and to what extent a large hip protects from type 2 diabetes and CVD
In a Lancet Diabetes & Endocrinology review article Norbert Stefan from the German Center for Diabetes Research (DZD), the University Hospital of Tübingen and the Boston Children’s Hospital, highlights why and to what extent a large hip circumference, an estimate…
2020 Warren Alpert Prize recognizes seminal discoveries in metabolism
Trio of researchers elucidated the role of gut hormones, enabling the design of treatments for diabetes, obesity, short bowel syndrome
New nanoparticle drug combination for atherosclerosis
Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. The CSNP-based combination drug delivery therapy was proved to exert cholesterol-lowering,…
Microbes might manage your cholesterol
Researchers discover mysterious bacteria that break down cholesterol in the gut
New nanoparticle drug combination for atherosclerosis
Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. The CSNP-based combination drug delivery therapy was proved to exert cholesterol-lowering,…
Microbes might manage your cholesterol
Researchers discover mysterious bacteria that break down cholesterol in the gut