news, journals and articles from all over the world.
A small genetic study, published September 30, 2019 in Nature Genetics, identified a protein linked to many genetic variants that affect heart function. Researchers are expanding the model to other organ systems and at larger scales to create a broader understanding of genes and proteins involved.
Rutgers-led study uses artificial intelligence to examine genetic signatures of inflammatory bowel illness
Whole genome sequencing of tumour cells could help predict the prognosis of a patient’s cancer and offer clues to identify the most effective treatment, suggests an international study published today in Nature Medicine . Our DNA, the human genome, comprises…
As their Latin name indicates, pineapples are truly “excellent fruits”–and thanks to a freshly completed genome sequencing project, researchers have gained a new understanding of how human agriculture has shaped the evolution of this and other crops. An international team…
A drug used for breast and ovarian cancer is more effective than modern targeted hormone treatments at slowing progression and improving survival in some men with advanced prostate cancer, phase III clinical trial findings reveal. The PROfound trial compared the…
Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. The new variant reduced unintended changes in DNA compared to its wildtype, suggesting it could play…
Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications. But since most of these variations fall into areas…
TORONTO, ON (Canada) – A team including evolutionary biologists from the University of Toronto (U of T) have identified the ways in which herbicide-resistant strains of an invasive weed named common waterhemp have emerged in fields of soy and corn…
Many new parents are familiar with terms like “baby brain” or “mommy brain” that hint at an unavoidable decline in cognitive function associated with the hormonal changes of pregnancy, childbirth, and maternal caregiving. A new study of parental care in…
New therapeutic targets
Some of the most important tools in the toolbox of modern cell biologists are special chunks of DNA that act like spies, reporting on the cell’s function. The markers, known as reporter genes, allow researchers to get a sense for…
New Cleveland Clinic led research published in American Journal of Human Genetics
If scientists could give living cells magnetic properties, they could perhaps manipulate cellular activities with external magnetic fields. But previous attempts to magnetize cells by producing iron-containing proteins inside them have resulted in only weak magnetic forces. Now, researchers reporting…
Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations
A group of researchers at Baylor College of Medicine, the Texas Heart Institute and the University of Texas Health Science Center at Houston reveals today in the journal Genes & Development new insights into the recently discovered healing capacity of…
PTEN, a tumor suppressor gene mutated in about 20% of prostate cancers, relies on another gene, ARID4B, to function. These findings were published by George Washington University Cancer Center researchers in Nature Communications.
Researchers from the George Washington University published their findings on the connection between the PTEN gene and the ARID4B gene in Nature Communications
Acute lymphoblastic leukemia (ALL), is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL than children without Down syndrome. Historically, children with Down syndrome and ALL had more…
A single gene in sorghum controls bird feeding behavior by simultaneously regulating the production of bad-tasting molecules and attractive volatiles, according to a study publishing September 23 in the journal Molecular Plant . This gene, called Tannin1, controls the synthesis…
If you could travel back in time 100,000 years, you’d find yourself living among multiple groups of humans, including anatomically modern humans, Neanderthals, and Denisovans. But exactly what our Denisovan relatives might have looked like had been anyone’s guess for…
A study recently published in the renowned journal Blood , led by Kaan Boztug, Scientific Director of the St. Anna Children’s Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Adjunct Principal Investigator at the CeMM…
Scientists have created a novel two-layer microchip to track individual developmental changes in stem cells over longer time periods
CLEMSON, South Carolina – A Clemson University professor’s research has documented the movement of antibiotic resistance in humans into animal species. College of Science researcher Vincent Richards recently published results that draw attention to reverse zoonosis, or pathogens moving from…
AUGUSTA, Ga. (Sept. 16, 2019) – Paul Tran is working to develop a highly predictive genetic risk score that will tell parents whether their baby is at significant risk for type 1 diabetes. The ultimate goal, says the MD/PhD student…
Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A University of Arizona researcher disputes that belief and hopes to change the paradigm even further.
Researchers from the University of Cambridge’s Sainsbury Laboratory (SLCU) and Department of Plant Sciences have discovered that drought stress triggers the activity of a family of jumping genes (Rider retrotransposons) previously known to contribute to fruit shape and colour in…
URBANA, Ill. – Corn, soybean, and cotton farmers shudder at the thought of Palmer amaranth invading their fields. The aggressive cousin of waterhemp – itself a formidable adversary – grows extremely rapidly, produces hundreds of thousands of seeds per plant,…
Researchers in Belgium present new findings on X chromosome reactivation
CHOP researchers: Finding may offer a key target for future treatments
Did you know that the DNA in any cell of the human body – or any organism for that matter – contains the genetic information required to develop every possible type of cell within that organism? Yet cell types differ…
Male honeybees inject queens with blinding toxins during sex
USC and Duke researchers say the framework illustrates how environmental and genetic factors interac
The key step in stomata development in plants has been discovered; genes that make stomata and enfor
Researchers have successfully sequenced the first genome of an individual from the Harappan civilization, also called the Indus Valley Civilization (IVC). The DNA, which belongs to an individual who lived four to five millennia ago, suggests that modern people in…
UH evolutionary biologist publishes findings on sex determinates of house flies
Modelling study estimates extent of river’s exposure to antibiotic-resistant bacteria
Microbes are well-known among biologists as master engineers of useful small molecules, and there are many tricks of their trade. When researchers at the University of Illinois took a closer look at how a known microbe makes a known so-called…
Region gives rise to serious disease, discovery could lead to new genetic testing
Boston Medical Center and Columbia University Irving Medical Center awarded grant for new trial
Researchers of the Josep Carreras Leukaemia Research Institute have discovered an epigenetic lesion
Our individuality is encrypted in our DNA, but it is deeper than expected
Protein-coding genes comprise a mere 1% of DNA. While the other 99% of DNA was once derided as “junk,” it has become increasingly apparent that some non-coding genes enable essential cellular functions. Wei Li, Ph.D., a principal investigator in the…
Meet the world’s first gene-edited reptiles: albino lizards roughly the size of your index finger. Researchers used CRISPR-Cas9 to make the lizards, providing a technique for gene editing outside of major animal models. In their study, publishing August 27 in…
The oldest parasite DNA ever recorded has been found in the ancient, desiccated feces of a puma
Further study is needed to determine if the altered gene contributes to autism in children
The identification of a molecular mechanism that causes lung cells to lose their identity, thereby p
Grow or defend yourself – a decision plants need to make on a daily basis, due to their inability to do both simultaneously. For a long time, it was thought that the reason for the growth-defence trade-off might be a…
Bacteria could be used to produce large quantities of medicines and fuels using a new gene programming technique, research suggests. The powerful method could enable bacteria to be used as cheap and environmentally friendly living factories that make a range…
Oncologists at VCU Massey Cancer Center were invited to co-author an editorial published in the Journal of Clinical Oncology providing expert commentary on findings from a large study conducted by German investigators that a modified drug combination may lead to…
Will support research on genes governing the health effects of chronic stress
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