Antiretroviral therapy can’t completely stop accelerated cell aging seen in HIV

FINDINGS Untreated HIV infection is linked with epigenetic changes that suggest rapid aging. A new study by UCLA researchers shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to…

Glutathione precursor GlyNAC reverses premature aging in people with HIV

Premature aging in people with HIV is now recognized as a new, significant public health challenge. Accumulating evidence shows that people with HIV who are between 45 to 60 years old develop characteristics typically observed in people without HIV that…

HIV epidemic: Successful use of self-tests in rural Africa

Despite significant progress in prevention and therapy, millions of people still get infected with HIV every year. The main burden of HIV/AIDS falls on Africa. To contain the epidemic, innovative methods are needed to enable early diagnosis of all those…

‘Repliclones’ fuel perplexing persistence of HIV in the blood of some patients on therapy

PITTSBURGH, Oct. 5, 2020 – Increasingly, UPMC’s chief of infectious diseases–a well-regarded expert in HIV/AIDS–is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus…

Scientists explore the obesity paradox, cardiovascular risk of HIV

The newer generation of HIV drugs have turned the once-lethal infection into a chronic condition, and cardiovascular disease has emerged as the leading cause of death in these individuals. Now, Medical College of Georgia scientists are dissecting the also emerging…

PLOS Special Collection launch: Populations HRSA serves

On September 2 2020, the open-access journals PLOS ONE & PLOS Medicine launched a Special Collection of manuscripts centered around the healthcare provided by the Health Resources and Services Administration (HRSA), the primary U.S. federal agency for improving healthcare in…

Rapid HIV, HCV testing at drug detoxification centers led to higher test result delivery

With an increase in HIV and HCV infections as a consequence of the ongoing opioid epidemic, Boston Medical Center researchers found that only a small number of those who test positive for those infections at a drug detoxification center followed…

Vaccine that harnesses antifungal immunity protects mice from staph infection

Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus ( S. aureus ) proteins protects mice against S. aureus infection, according to a study published August 20 2020 in the open-access journal PLOS Pathogens…

USPSTF recommendation on behavioral counseling to prevent sexually transmitted infections

Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends behavioral counseling to prevent sexually transmitted infections (STIs) for all sexually active adolescents and for adults at increased risk. Sexually transmitted infections are on the rise across the United States,…

Multiple sclerosis drug blocks HIV infection and transmission in human immune cells

An immunomodulatory drug called fingolimod, which is approved for the treatment of multiple sclerosis, blocks human immunodeficiency virus (HIV) infection and transmission in human immune cells, according to a study published August 13 in the open-access journal PLOS Pathogens by…

Mount Sinai’s Arnhold Institute for Global Health partners with NYC Health + Hospitals on COVID-19 Unit for Research at Elmhurst (CURE-19)

(New York, NY – August 12, 2020) – The Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai and NYC Health + Hospitals have launched the COVID-19 Unit for Research at Elmhurst (CURE-19). The new…