FINDINGS Untreated HIV infection is linked with epigenetic changes that suggest rapid aging. A new study by UCLA researchers shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to…
Tag: AIDS/HIV
Researchers investigating influence of sex hormones on HIV cure strategies
A research team at the George Washington University is investigating whether and how sex hormones influence cure strategies for HIV
Researchers explore at-home testing method of viral loads for HIV patients
UNIVERSITY PARK, Pa. — Development of a new method to monitor the effectiveness of human immunodeficiency virus (HIV) treatment at home instead of in hospitals is underway by Penn State researchers. The research is supported by a three-year, $1,012,996 grant…
Unique program aims to educate Muslim teens on HIV prevention
October 19, 2020 – Cultural taboos may leave Muslim American adolescents uninformed about romantic relationships and sex, placing them at risk of HIV and other sexually transmitted infections (STIs) . A sex education program designed specifically for Muslim teens –…
New research comparing HIV medications set to change international recommendations
A new study by UBC researchers is set to change international treatment recommendations for people who are newly diagnosed with HIV–an update that could affect nearly two million people per year worldwide. The study, published today by The Lancet in…
Glutathione precursor GlyNAC reverses premature aging in people with HIV
Premature aging in people with HIV is now recognized as a new, significant public health challenge. Accumulating evidence shows that people with HIV who are between 45 to 60 years old develop characteristics typically observed in people without HIV that…
Results from the REFLECT II Trial reported at TCT Connect
Randomized trial studies device designed to reduce embolic events in patients undergoing TAVR
Many college students aren’t tested for STIs despite high rates, self-tests offer promise
New George Mason University study highlights opportunity to increase testing for sexually transmitted infections among this high-risk population
Updated recommendations for preventing, treating HIV infection
What The Study Did: New evidence on preventing and treating HIV infection in adults was reviewed to update practice recommendations from the International Antiviral (formerly AIDS) Society-USA. Authors: Michael S. Saag, M.D., of the University of Alabama at Birmingham, is…
HIV epidemic: Successful use of self-tests in rural Africa
Despite significant progress in prevention and therapy, millions of people still get infected with HIV every year. The main burden of HIV/AIDS falls on Africa. To contain the epidemic, innovative methods are needed to enable early diagnosis of all those…
HIV and lung cancer in East Africa: CWRU and UH secure research funds
Collaboration includes multiple East African Research Centers
HSE University researcher develops global HIV prevention index for drug users
Russia ranked 59th among 105 countries around the world
Molecular mechanism of cross-species transmission of primate lentiviruses
Principle of lentiviral cross-species transmission leading to the emergence of the AIDS virus
How immune cells can recognise – and control – HIV when therapy is interrupted
New findings reveal how HIV-1-specific immune cells can recognise viral particles that have the capacity to rebound following interruptions to antiretroviral therapy, with implications for new treatment strategies
‘Repliclones’ fuel perplexing persistence of HIV in the blood of some patients on therapy
PITTSBURGH, Oct. 5, 2020 – Increasingly, UPMC’s chief of infectious diseases–a well-regarded expert in HIV/AIDS–is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus…
Chicago Center for HIV Elimination awarded $5M for community COVID-19 testing and prevention
New funding from the NIH’s rapid acceleration of diagnostics program supports social network strategy to encourage COVID-19 testing in disenfranchised populations
Ezintsha study provides new data on current ART regimens with concerns about weight gain
Wits researchers today publish major findings from the ADVANCE research study, conducted in central Johannesburg, looking at the potency and safety of SA’s commonly used antiretroviral treatment regimens
A first in-depth look at the latent virus reservoir of individuals living with HIV
New study opens avenues for studying or targeting the main barrier to a cure
Study explores link between methamphetamine use and risky sexual behavior
The illicit drug makes some users more likely to risk sex without a condom
Study links low immunity to poor outcomes in patients with HIV who contract COVID-19
Age and underlying health conditions also associated with decreased survival
CU researcher: Outdated corneal donation policies prevent sight-restoring surgery
AURORA, Colo. (Sept. 24, 2020) – Some forms of blindness and visual impairment can be cured with a corneal transplant surgery using donated eye tissue. However, federal regulations in the United States and Canada severely restrict the ability of sexually…
Study examines women’s attitudes toward long-acting injectable therapy to prevent HIV
Oral pre-exposure prophylaxis (PrEP) is a highly effective method of reducing risk for HIV, yet use of PrEP is uniformly low, especially among women. As a result, researchers have developed long-acting injectable (LAI) versions of PrEP, one version of which…
Many practitioners are not prescribing HIV prevention medication, study finds
Only about 54% of medical practitioners surveyed say they have prescribed pre-exposure prophylaxis, or PrEP, to HIV-vulnerable patients, according to a new study by a Vanderbilt University Medical Center investigator. The study, led by Ashley Leech, PhD, assistant professor of…
Medical mistrust grounded in structural and systemic racism affects HIV care for Black women in the US South
September 17, 2020 – For Black women in the southern United States, mistrust of the health care system that is grounded in structural and systemic racism is a key factor affecting participation in HIV prevention and treatment services , reports…
Scientists explore the obesity paradox, cardiovascular risk of HIV
The newer generation of HIV drugs have turned the once-lethal infection into a chronic condition, and cardiovascular disease has emerged as the leading cause of death in these individuals. Now, Medical College of Georgia scientists are dissecting the also emerging…
The pharmacist’s role in HIV care in France
In France, antiretroviral treatment (ARV) can be dispensed by hospitals and/or community pharmacies. A recent study published in Pharmacology Research & Perspectives examined the pharmacist’s role in HIV care in this country. For the study, 2 national surveys were sent.…
Penn Medicine researcher receives early career honor from Burroughs Wellcome Fund
Award will support research on understanding the epigenetic mechanisms of HIV persistence
Male circumcision campaigns in Africa to fight HIV are a form of cultural imperialism
Male circumcision campaigns in Africa to fight HIV ‘neocolonialist’ and not based on robust science
Antibiotic molecule enables immune system to kill HIV infected cells
Researchers have discovered an unexpected potential weapon against HIV protein
MIT press first reads series continues with ‘Viruses, pandemics, and immunity’
From MIT’s Arup K. Chakraborty and immunologist Andrey Shaw
US aid restrictions reduce delivery of key health services for PEPFAR beneficiaries
In 2017, the Trump administration reinstated and expanded the Mexico City Policy, officially titled Protecting Life In Global Health Assistance. This policy prohibits any US-based or foreign nongovernmental organization from receiving US government global health assistance unless the organization certifies…
Prophylactic antivirals prevent chronic HCV in patients receiving kidneys from positive donors
Embargoed News from Annals of Internal Medicine
PLOS Special Collection launch: Populations HRSA serves
On September 2 2020, the open-access journals PLOS ONE & PLOS Medicine launched a Special Collection of manuscripts centered around the healthcare provided by the Health Resources and Services Administration (HRSA), the primary U.S. federal agency for improving healthcare in…
Gene therapy research for HIV awarded $14.6 million NIH grant
Collaboration co-led by Keck School of Medicine of USC aims for safe, effective treatment inspired by rare cases of HIV cure
Rapid HIV, HCV testing at drug detoxification centers led to higher test result delivery
With an increase in HIV and HCV infections as a consequence of the ongoing opioid epidemic, Boston Medical Center researchers found that only a small number of those who test positive for those infections at a drug detoxification center followed…
Antiretroviral therapy fails to treat one-third of HIV patients in Malawi hospital
Researchers call for new rapid tests to combat HIV drug resistance in sub-Saharan Africa
Researchers begin safety study of dapivirine ring and oral PrEP in breastfeeding women
Similar study testing same HIV prevention methods in pregnant women already underway
Novel Dual CAR T cell immunotherapy holds promise for targeting the HIV reservoir
BOSTON- A recent study published in the journal Nature Medicine, led by researchers Todd Allen, PhD, a professor of Medicine at Harvard Medical School (HMS) and group leader at the Ragon Institute of MGH, MIT and Harvard, and Jim Riley,…
New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
BOSTON – A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.…
Unique HIV reservoirs in elite controllers
Ragon Institute researchers show elite controllers have HIV viral reservoirs in gene deserts which may help prevent viral rebound and contribute to natural control of HIV.
Severe viral infection overwhelms immune cells
Melbourne researchers have identified mechanisms leading to the functional deterioration of the immune system in response to severe viral infections, such as HIV or COVID-19.
Finding clues to a successful immune response in the T cells of COVID-19 patients
While antibodies may fade fast, T cells appear to be long-lived and might confer lasting immunity.
Long-acting, injectable drug could strengthen efforts to prevent, treat HIV
Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects. The drug, which was tested in non-human primates, could eventually replace or…
Vaccine that harnesses antifungal immunity protects mice from staph infection
Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus ( S. aureus ) proteins protects mice against S. aureus infection, according to a study published August 20 2020 in the open-access journal PLOS Pathogens…
Young gay men’s health care needs not being met
Discrimination and health care providers’ lack of knowledge may lead to missed screenings and care, Rutgers study finds
USPSTF recommendation on behavioral counseling to prevent sexually transmitted infections
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends behavioral counseling to prevent sexually transmitted infections (STIs) for all sexually active adolescents and for adults at increased risk. Sexually transmitted infections are on the rise across the United States,…
How viral infections associated with cancer become persistent?
Study discovers novel functions of viral protein
Multiple sclerosis drug blocks HIV infection and transmission in human immune cells
An immunomodulatory drug called fingolimod, which is approved for the treatment of multiple sclerosis, blocks human immunodeficiency virus (HIV) infection and transmission in human immune cells, according to a study published August 13 in the open-access journal PLOS Pathogens by…
Mount Sinai’s Arnhold Institute for Global Health partners with NYC Health + Hospitals on COVID-19 Unit for Research at Elmhurst (CURE-19)
(New York, NY – August 12, 2020) – The Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai and NYC Health + Hospitals have launched the COVID-19 Unit for Research at Elmhurst (CURE-19). The new…
NIH grant to UC Riverside physicist focuses on how pathogens evolve
Research could lead to the design of new and better treatments to fight disease