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UrduA multidisciplinary team of researchers is the first to show combining yeast-expression technology and a novel adjuvant formulation to produce a COVID-19 vaccine candidate is effective against SARS-COV-2 and promises to be easy to produce at large scale and cost-effective, important aspects for vaccinating people worldwide, especially in low- to middle-income countries.
Tag: INFECTIOUS/EMERGING DISEASES
The Lancet: One in two hospitalized COVID-19 patients develop a complication
Study is most comprehensive of its kind and included more than 70,000 adults in the UK hospitalised with severe COVID-19 disease. Of these, half (36,367 of 73,197) developed one or more health complication during their hospitalisation. Most common complications included…
Human waste contaminating urban water leads to ‘superbug’ spread — study
Contamination of urban lakes, rivers and surface water by human waste is creating pools of ‘superbugs’ in Low- and Middle-Income Countries (LMIC) – but improving access to clean water, sanitation and sewerage infrastructure could help to protect people’s health, a…
Heart problems resolve in majority of kids with COVID inflammatory syndrome
NEW YORK, NY (July 15, 2021)–Heart problems in children hospitalized with multisystem inflammatory syndrome (MIS-C)–an inflammatory condition triggered by COVID–were mostly gone within a few months, a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons…
Pandemic of antibiotic resistance is killing children in Bangladesh
BOSTON – Resistance to antibiotics is common and often deadly among children with pneumonia in Bangladesh, according to a new study coauthored by researchers from Massachusetts General Hospital (MGH) with colleagues at the International Centre for Diarrhoeal Disease Research, Bangladesh…
Identification of over 200 long COVID symptoms prompts call for UK screening programme
Patients who experience long COVID have reported more than 200 symptoms across 10 organ systems*, in the largest international study of ‘long-haulers’ to date, led by UCL scientists together with a patient-led research collaborative. For the study, published in the…
ComCor study on SARS-CoV-2: where are French people catching the virus?
ComCor study on places of infection with SARS-CoV-2: where are French people catching the virus?
Launch of UNITE4TB partnership marks a new era in Tuberculosis treatment development
The partnership will accelerate the development of new Tuberculosis (TB) drug regimens as part of the Innovative Medicines Initiative (IMI), a public-private European Research & Development Consortium
Press registration opens for ACS Fall 2021 meeting
WASHINGTON, July 15, 2021 — Journalists who register for the fall meeting of the American Chemical Society (ACS) will have access to more than 7,000 presentations on topics including agriculture and food, energy and fuels, health and medicine, space science,…
Children’s National Hospital joins the Mendelian Genomics Research Consortium, receiving $12.8 million
The National Institutes of Health’s National Human Genome Research Institute award will help discover inherited rare diseases and conditions in children
Association of remdesivir treatment with survival, length of hospital stay among US veterans hospitalized with COVID-19
What The Study Did: I n this observational study using data from the Veterans Health Administration for 2,344 U.S. veterans hospitalized with COVID-19, remdesivir treatment was associated with prolonged hospitalization but wasn’t associated with improved survival. Authors: Michael E. Ohl,…
Sociodemographic characteristics, inequities associated with access to in-person, remote elementary schooling during pandemic in New York State
What The Study Did: Among the few New York state public school districts providing full-time in-person elementary school instruction during the COVID-19 pandemic, most districts served predominately white students, rural/suburban students and children who were not disadvantaged (children who were…
Inadequate sequencing of SARS-CoV-2 variants impedes global response to COVID-19
Better international sequencing efforts are needed to track and respond to new SARS-CoV-2 variants
Effect of physician-delivered COVID-19 public health messages on adults’ knowledge, beliefs, practices related to COVID-19
What The Study Did: In this randomized clinical trial, a physician messaging campaign was effective in increasing COVID-19 knowledge, information-seeking and self-reported protective behaviors among diverse groups. Authors: Esther Duflo, Ph.D., of the Massachusetts Institute of Technology in Cambridge, is…
Symptoms of depression, anxiety among women experiencing homelessness/unstable housing during pandemic
What The Study Did: About half the women experiencing homelessness and unstable housing who were surveyed experienced symptoms of depression or anxiety or both during the pandemic and, in addition to unmet subsistence needs and social isolation, these symptoms were…
USGS-led study helps in the fight against the coronavirus pandemic
Scientists provide a more strategic approach to COVID-19 testing
Short chain fatty acids: An ‘ace in the hole’ against SARS-CoV-2 infection
Scientists find that short chain fatty acids can be used to reduce susceptibility to SARS-CoV-2 infection and mortality from COVID-19
Like priming a pump, cells damaged by chronic lung disease can result in severe COVID
Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases
Prevention, detection and various approaches on coronaviruses
In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential. This book Coronavirus brings together essential data regarding prevention…
Vaccine hesitancy in young adults may hamper herd immunity
Questions about safety, side effects preclude youth from getting COVID shot, UCSF study shows
Early perceptions of COVID-19 in Pennsylvania
Knowledge, perceptions, and preferred information sources related to COVID-19 among central Pennsylvania adults early in the pandemic: A mixed methods cross-sectional survey
July/August 2021 Annals of Family Medicine tip sheet
Primary Care Poised to Provide Clinical Guidance, Answers About COVID-19 Testing, Vaccine Administration Researchers examined the role of primary care physicians and other clinicians in delivering vaccinations in the United States. They used two main datasets to create an in-depth…
Primary care provides clinical guidance, answers about COVID-19 testing, vaccine
Primary care’s historic role in vaccination and potential role in COVID-19 immunization programs
Role of subnuclear NSrp70 in immunity-studied at Gwangju Institute of Science & Technology
Scientists report that the alternative-splicing regulator NSrp70 influences immune T cell development
Association of socioeconomic characteristics with disparities in COVID-19 outcomes in Japan
What The Study Did: This study found an unequal pattern of COVID-19 outcomes that was associated with the socioeconomic circumstances in regions of Japan, suggesting that these disparities in COVID-19 outcomes aren’t unique to the United States and Europe. Authors:…
Changes in admissions to specialty addiction treatment facilities in California during COVID-19 pandemic
What The Study Did: T he COVID-19 pandemic was associated with a decline in addiction treatment initiations but more research is needed to understand the cause of the decline in initiations and the extent to which it was due to…
One shot of the Sputnik V vaccine triggers strong antibody responses
A single dose of the Sputnik V vaccine may elicit significant antibody responses against SARS-CoV-2, finds a study published July 13 in the journal Cell Reports Medicine.
Supermarket model to guide safer shopping amid pandemic
A Skoltech team has developed a model for assessing infection risks for supermarket customers. The researchers believe that their model will help formulate scientifically backed rules for safe shopping during the pandemic. The paper was published in PLOS One .…
Allocating COVID vaccines based on health and socioeconomic factors could cut mortality
Study suggests spatial relationship between COVID-19 mortality and population-level health factors
Study assesses the prevalence of mental illness during the pandemic among folks aged 50-80
The study was conducted in the city of São Paulo, with over 2,000 participants who were active or retired staff of the University of São Paulo and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil).
Early anticoagulant treatment shown to reduce death in moderately ill COVID-19 patients
International RAPID Trial could contribute to clinical practice
COVID-19 hospitalization and mortality: Sex differences
New Rochelle, NY, July 13, 2021–Males with COVID-19 had significantly higher rates of hospitalization and of transfer to the intensive care unit (ICU) according to a new study. A higher percentage of males died of COVID-19 compared to females, as…
Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality
Study suggests spatial relationship between COVID-19 mortality and population-level health factors
Study: Racial/ethnic and language inequities in ways patients obtain COVID-19 testing
The COVID-19 pandemic caused an unprecedented disruption to health care delivery, with resources shifted toward telehealth services and mass viral testing. While early studies in the pandemic highlighted differences in health care utilization among patients with commercial insurance, data from…
GARDP, CHAI and Shionogi announce MOU to increase access to antibiotic
The Global Antibiotic Research and Development Partnership (GARDP), the Clinton Health Access Initiative (CHAI) and Shionogi & Co., Ltd today announced a Memorandum of Understanding (MOU) to accelerate access, including in low- and middle-income countries, to the antibiotic cefiderocol for…
Every spot of green space counts
The city park may be an artificial ecosystem but it plays a key role in the environment and our health, the first global assessment of the microbiome in city parks has found.
Neither remdesivir nor HCQ affect viral clearance in hospitalized patients with COVID-19
Embargoed news from Annals of Internal Medicine
PCORI approves $11 million for studies to boost COVID-19 vaccination among long-term care workers
Results could help boost immunization rates during and beyond pandemic among key health care workers
New study: Lack of consideration of sex and gender in COVID-19 clinical studies
Although Covid-19 affects men and women differently, the large majority of current clinical studies of SARS-CoV-2 and COVID-19 makes no mention of sex/gender. Indeed, only a fraction, 4 percent, explicitly plan to address sex and gender in their analysis, concludes…
The incidence of COVID-19 in a Brazilian regional soccer league is one of the highest
Researchers analyzed almost 30,000 RT-PCR tests on swabs from 4,269 players in 2020: 11.7% turned out positive; the rate was the same as among front-line health workers
Neonatal meningitis: the immaturity of microbiota and epithelial barriers implicated
Meningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population. Group B streptococcus (GBS) bacteria are the most…
Sensitivity of the Delta variant to sera from convalescent and vaccinated individuals
COVID-19: analysis of the sensitivity of the Delta variant to monoclonal antibodies and sera from convalescent and vaccinated individuals
Changes in care delivery during COVID-19
What The Study Did: Researchers characterized clinical content of ambulatory care among office-based compared with telemedicine visits in the United States before and during the COVID-19 pandemic. Authors: G. Caleb Alexander, M.D., M.S., of the Johns Hopkins Bloomberg School of…
Disparities in vaccine acceptance among adults in China
What The Study Did: This survey study examined disparities in COVID-19 vaccine acceptance and approaches to improve vaccination rates among adults in China. Authors: Jingjing Ma, Ph.D., of Peking University in Beijing, is the corresponding author. To access the embargoed…
Packaged water consumption linked to cholera outbreak in DRC capital
Cholera is a diarrheal disease caused by ingestion of the Vibrio cholerae bacterium. In November 2017, a cholera epidemic occurred in Kinshasa, the Democratic Republic of the Congo, where no outbreak had been recorded for nearly a decade. A study…
Arab participation in global genomic study could lead to new therapies for COVID patients
Researchers from Qatar Foundation Research, Development, and Innovation’s Qatar Genome Programme contribute toward global initiative that can lead to therapeutic targets in addition to the protection conferred by the vaccines
The Lancet: CoronaVac COVID-19 vaccine is safe and protects against disease, interim analysis
Interim data from a phase 3 trial of a COVID-19 vaccine developed in China (CoronaVac) suggests that two doses offer 83.5% protection against symptomatic COVID-19. The preliminary findings, published in The Lancet and presented at this year’s European Congress of…
Inhaled COVID-19 vaccine prevents disease and transmission in animals
In a new study assessing the potential of a single-dose, intranasal COVID-19 vaccine, a team from the University of Iowa and the University of Georgia found that the vaccine fully protects mice against lethal COVID-19 infection. The vaccine also blocks…
Biomaterial vaccines ward off broad range of bacterial infections and septic shock
A new vaccine technology combining capture of bacterial pathogens with effective immune-reprogramming biomaterials could be applied to a broad spectrum of infectious diseases