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UrduA molecule that suppresses melanoma tumours has been identified at the University of Bath
Tag: genes
Hyperactive immune system gene causes schizophrenia-like changes in mice
Excessive activity of an immune system gene previously linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study publishing on January 14 in the open-access journal PLOS Biology by Ashley Comer and…
Newly discovered genetic element adjusts coat color in dogs
Why are Irish Setters so red? Geneticists at the UC Davis School of Veterinary Medicine now have an answer for why some dogs have more intense coat colors than others. While their wolf ancestors are muted in color, domestic dogs…
Michael J. Bamshad, MD, named inaugural Editor-in-Chief of HGG Advances
New open access journal to launch in 2020
Opening up DNA to delete disease
Custom-built molecules enable editing of genes previously obscured by DNA’s innately protective structure
Two cancer-causing genes work together to promote metastasis
Two genes that promote cancer development, MYC and TWIST1, work together to recruit immune cells to tumours, creating an environment that enables cancer cells to spread
New E. coli-infecting bacteriophage introduced in PHAGE
New Rochelle, NY, January 14, 2020–A new coliphage – a bacteriophage that infects and can destroy Escherichia coli — is presented and characterized in PHAGE: Therapy, Applications, and Research , a new peer-reviewed journal from Mary Ann Liebert, Inc., publishers…
Skin cancer suppressor found by Bath scientists
A molecule that suppresses melanoma tumours has been identified at the University of Bath
Michael J. Bamshad, MD, named inaugural Editor-in-Chief of HGG Advances
New open access journal to launch in 2020
Opening up DNA to delete disease
Custom-built molecules enable editing of genes previously obscured by DNA’s innately protective structure
Research identifies possible on/off switch for plant growth
Protein could be key to saving crops endangered by extreme weather
Directed evolution of endogenous genes opens door to rapid agronomic trait improvement
A research team led by Profs. GAO Caixia and LI Jiayang from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have engineered five saturated targeted endogenous mutagenesis editors (STEMEs) and generated de novo mutations to…
Research identifies new route for tackling drug resistance in skin cancer cells
Researchers have found that melanoma cells fight anti-cancer drugs by changing their internal skeleton (cytoskeleton) – opening up a new therapeutic route for combatting skin and other cancers that develop resistance to treatment. The team, led by Queen Mary University…
Research identifies possible on/off switch for plant growth
Protein could be key to saving crops endangered by extreme weather
Research identifies possible on/off switch for plant growth
Protein could be key to saving crops endangered by extreme weather
Directed evolution of endogenous genes opens door to rapid agronomic trait improvement
A research team led by Profs. GAO Caixia and LI Jiayang from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have engineered five saturated targeted endogenous mutagenesis editors (STEMEs) and generated de novo mutations to…
Directed evolution of endogenous genes opens door to rapid agronomic trait improvement
A research team led by Profs. GAO Caixia and LI Jiayang from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have engineered five saturated targeted endogenous mutagenesis editors (STEMEs) and generated de novo mutations to…
Research identifies new route for tackling drug resistance in skin cancer cells
Researchers have found that melanoma cells fight anti-cancer drugs by changing their internal skeleton (cytoskeleton) – opening up a new therapeutic route for combatting skin and other cancers that develop resistance to treatment. The team, led by Queen Mary University…
Research identifies new route for tackling drug resistance in skin cancer cells
Researchers have found that melanoma cells fight anti-cancer drugs by changing their internal skeleton (cytoskeleton) – opening up a new therapeutic route for combatting skin and other cancers that develop resistance to treatment. The team, led by Queen Mary University…
Specific insulin-like peptide regulates how beetle “weapons” grow
Revealing how larval nutrition leads to differently sized mandibles in broad-horned flour beetles
New function for potential tumor suppressor in brain development
Analysis of Cdkn1c loss at single cell level reveals novel and unexpected role of gene — study published in Nature Communications
Chromatin organizes itself into 3D ‘forests’ in single cells
Knowledge could help scientists understand chromatin’s role in cancer, other diseases
Gene network helps to turn white fat into beneficial calorie-burning fat
A new approach to treating overweight and obesity
The claw disease tyloma is primarily genetic in cows
Scientists at Martin Luther University Halle-Wittenberg (MLU) and Georg August University Göttingen have succeeded in proving that a claw disease in cows is primarily genetic. Until now, the occurrence of interdigital hyperplasia has mostly been attributed to poor hygiene conditions…
Discovery of gene that modifies the severity of inherited kidney disease
Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalised treatments. Experts at Newcastle University, UK, have shown that the rate…
Common plasticizer disrupts C. elegans egg production
Low doses of phthalate cause increased double-strand breaks in DNA during roundworm egg formation
Missing protein in brain causes behaviors mirroring autism
Rutgers-Newark scientists are studying whether there is a genetic link to autism spectrum disorder and Alzheimer’s disease
Common genetic defect in prostate cancer inspires path to new anti-cancer drugs
(Philadelphia, PA) – Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell…
Gene network helps to turn white fat into beneficial calorie-burning fat
A new approach to treating overweight and obesity
The claw disease tyloma is primarily genetic in cows
Scientists at Martin Luther University Halle-Wittenberg (MLU) and Georg August University Göttingen have succeeded in proving that a claw disease in cows is primarily genetic. Until now, the occurrence of interdigital hyperplasia has mostly been attributed to poor hygiene conditions…
Discovery of gene that modifies the severity of inherited kidney disease
Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalised treatments. Experts at Newcastle University, UK, have shown that the rate…
Common plasticizer disrupts C. elegans egg production
Low doses of phthalate cause increased double-strand breaks in DNA during roundworm egg formation
Missing protein in brain causes behaviors mirroring autism
Rutgers-Newark scientists are studying whether there is a genetic link to autism spectrum disorder and Alzheimer’s disease
Common genetic defect in prostate cancer inspires path to new anti-cancer drugs
(Philadelphia, PA) – Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell…
The nation’s leading prostate cancer nonprofit responds to 2020 Cancer Facts and Figures
2020 prostate cancer death tolls to be highest in two decades
The use of fetal exome sequencing in prenatal diagnosis: A new ACMG Points to Consider
A new Points to Consider document from the ACMG aims to assist referring physicians, laboratory geneticists, genetic counselors and other medical professionals in understanding the complexity and implications of exome sequencing (ES) in prenatal care. Published in ACMG’s official journal…
Researchers discover a new auto-inflammatory disease called CRIA syndrome
Mutations in the RIPK1 gene responsible for CRIA syndrome
Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice
CNIO researchers and authors of the finding want to start clinical trials
Abnormal neuron activity manifests as parental neglect
The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child matures and…
MDI biological scientists identify pathways that extend lifespan by 500%
Discovery of cellular mechanisms could open door to more effective anti-aging therapies
The use of fetal exome sequencing in prenatal diagnosis: A new ACMG Points to Consider
A new Points to Consider document from the ACMG aims to assist referring physicians, laboratory geneticists, genetic counselors and other medical professionals in understanding the complexity and implications of exome sequencing (ES) in prenatal care. Published in ACMG’s official journal…
Researchers discover a new auto-inflammatory disease called CRIA syndrome
Mutations in the RIPK1 gene responsible for CRIA syndrome
Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice
CNIO researchers and authors of the finding want to start clinical trials
Abnormal neuron activity manifests as parental neglect
The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child matures and…
The nation’s leading prostate cancer nonprofit responds to 2020 Cancer Facts and Figures
2020 prostate cancer death tolls to be highest in two decades
MDI biological scientists identify pathways that extend lifespan by 500%
Discovery of cellular mechanisms could open door to more effective anti-aging therapies
New compounds block master regulator of cancer growth, metastasis
CHAMPAIGN, Ill. — Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and in mouse models…
New compounds block master regulator of cancer growth, metastasis
CHAMPAIGN, Ill. — Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and in mouse models…
Rutgers Expert Available to Discuss Coral Genomics Paper
New Brunswick, N.J. (Jan. 6, 2020) – By combining a range of biological data with the first successful genome editing experiments in corals, scientists are poised for rapid advancements in understanding how coral genes function, according to a paper in…
Researchers suggest a pathway to reverse the genetic defect of Friedreich’s ataxia
The neurodegenerative disease is marked by an expansion of DNA triplet repeats; the Tufts researchers pinpoint a mechanism for potentially reversing the expansion