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UrduArtificial intelligence tool can be used for long-term tracking and management of chronic gastrointestinal ailments
Tag: Gastroenterology
Long-term gluten intake, cognitive function among women
What The Study Did: This observational study found no association between long-term dietary intake of gluten and cognitive function among a large group of middle-age women without celiac disease. Authors: Andrew T. Chan, M.D., M.P.H., of Massachusetts General Hospital and…
Carbohydrate ‘cage’ allows precise drug delivery to the gastrointestinal tract
A GlycoCage technology developed by GlycoNet researchers aims to improve current treatments for inflammatory bowel disease
Western diet found to impair function of immune cells in the gut
Cleveland Clinic-led researchers publish findings in Cell Host & Microbe
’45 is the new 50′ as age for colorectal cancer screening is lowered
BOSTON – Prompted by a recent alarming rise in cases of colorectal cancer in people younger than 50, an independent expert panel has recommended that individuals of average risk for the disease begin screening exams at 45 years of age…
USPSTF lowers recommended ages for colorectal cancer screening
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends that adults ages 45 to 75 be screened for colorectal cancer, lowering the age for screening that was previously 50 to 75. The USPSTF also recommends that clinicians selectively offer…
Western diet may increase risk of gut inflammation, infection
Diet rich in sugar, fat damages immune cells in digestive tracts of mice
Which medications are most toxic to the liver?
A new study published in the British Journal of Clinical Pharmacology ¬provides insights on how common hospitalized patients develop liver injury from taking different medications. When investigators analyzed the records of 156,570 hospitalized patients, they found 499 cases of drug-induced…
May Issue of The American Journal of Gastroenterology Contains Two Updated ACG Clinical Guidelines: Upper GI Bleeding and Drug-Induced Liver Injury
newly issued updates to ACG Clinical Guidelines on Upper Gastrointestinal and Ulcer Bleeding and Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. In addition to the guidelines, this issue features clinical research on esophageal cancer, obesity, telemedicine, celiac disease, Crohn’s disease, and more.
Intestinal polyps in close relatives can increase risk of colorectal cancer
Cancer of the colon and rectum is one of the deadliest forms of cancer, and has in recent years affected growing numbers of young people. In the largest registry study to date, researchers at Karolinska Institutet in Sweden and Harvard…
Increased use of minimally invasive non-endoscopic tests for Barrett’s esophagus screening
Embargoed news from Annals of Internal Medicine
A glimmer of hope: New weapon in the fight against liver diseases
Niigata, Japan–Researchers from Niigata University , the University of Tokyo, Osaka University and Tokyo Medical University, Japan have developed a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damages caused by liver diseases. This novel…
SARS-CoV-2 curtails immune response in the gut
Scientists transform human intestinal cells into ‘mini guts’ to follow infection process
Personalized, 3D printed shields developed to protect patients during radiation therapy
To reduce tissue injury side effects from radiation therapy, a research team is developing 3D-printed gastrointestinal radioprotective devices that can be generated from patient CT scans
Probiotic Lactobacillus acidophilus shows promise for treating inflammatory bowel disease and other
Probiotic strain LA1 has a therapeutic effect that both prevents and treats intestinal inflammatory disorders caused by “leaky gut,” report researchers in The American Journal of Pathology
April Issue of The American Journal of Gastroenterology Highlights Dietary Interventions to Address Common Upper GI Complaints
Also: Opioid prescription rates for GI conditions, evolving changes in fecal microbiota transplantation risk, endoscopy challenges in patients with surgically altered anatomy, insulin resistance and pancreatic cancer risk, comparing clinician and insurer perspectives to managing IBS, and more.
AGA recommends intragastric balloons as an additional weight loss strategy for obese patients
The American Gastroenterological Association (AGA) issues formal recommendations on the use of intragastric balloons for obesity
Gut microbiota in cesarean-born babies catches up
Infants born by cesarean section have a relatively meager array of bacteria in the gut. But by the age of three to five years they are broadly in line with their peers.
Possible trigger for Crohn’s disease identified
Adherent-invasive E-coli (AIEC) strongly implicated
Gut microbiota in cesarean-born babies catches up
Infants born by cesarean section have a relatively meager array of bacteria in the gut. But by the age of three to five years they are broadly in line with their peers. This is shown by a study that also…
Targeted opioid that hones in on inflamed tissues stops colitis pain without side effects
Study in mice points to promising treatment for pain in inflammatory bowel disease
Diets high in heat-treated foods increase risk of chronic kidney disease, rat study shows
Processed foods drive intestinal barrier permeability and microvascular diseases
Mount Sinai study reveals genetic and cellular mechanisms of Crohn’s disease
Mount Sinai researchers have identified genetic and cellular mechanisms of Crohn’s disease, providing new insights for future treatments that could offer a tailored approach to patients with the chronic inflammatory disease, according to a study published in Nature on March…
Chronic inflammatory liver disease: cell stress mechanisms identified
International study led by MedUni Vienna appears in “Hepatology”
Open-label placebo works as well as double-blind placebo in irritable bowel syndrome
First-of-its-kind study compares performance of open-label placebo to blinded placebo
High-fiber diet may play a role in controlling the inflammation associated with COVID-19
In vitro treatment of cells with these molecules reduced the expression of a gene that plays a key role in viral cell entry and a cytokine receptor.
How much peanut does it take to trigger an allergic reaction?
University of Cincinnati toxicologist says finding an ‘eliciting dose’ may help those who suffer mild or moderate allergic reactions to peanut
New study published in Science maps wildlife microbiota
Discovering millions of previously unknown potential human therapeutics
A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation
This study will aid the understanding of, and future research on, inflammatory bowel disease, which afflicts about 1.6 million Americans
Aging cells in abdominal fluid cause increased peritoneal dissemination of gastric cancer
Closing in on complete control over peritoneal dissemination of cancer.
Study estimates rising global burden of gallbladder and biliary tract cancer
Although cancers that occur in the gallbladder or bile ducts are rare, their rates are increasing. A recent study provides details on the burden of gallbladder and biliary tract cancer (GBTC) across 195 countries and territories from 1990 to 2017.…
New Barrett’s esophagus monitoring method could aid in easier and more precise prognoses
CLEVELAND–A new technique for sampling and testing cells from Barrett’s esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according…
Common, serious gut disorder is under- and often misdiagnosed
A serious digestive problem that is underdiagnosed–rumination–is highlighted in a new study.
Reversing cancer’s gluttony
Researchers report that pancreatic cancer tumors use multiple mechanisms to avoid starvation, suggesting a new target for treating a very difficult and deadly disease
A raw diet for under 6-month-old puppies may reduce the risk of inflammatory bowel disease
According to a study conducted at the University of Helsinki, a raw diet from the late stages of suckling to roughly two months of age may reduce the prevalence of inflammatory bowel disease (IBD) in dogs later in life. In…
Scientist gets $2 million grant to study how inflammation, gut microbiota promote metabolic syndrome
ATLANTA–Dr. Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year federal grant just over $2 million to study how inflammation and altered gut microbiota, the microorganisms living in the intestine, influence…
Surgery should remain as mainstay of treatment for acute uncomplicated appendicitis
An RCSI study conducted in Beaumont Hospital in Dublin has found that surgery, rather than antibiotics-only, should remain as the mainstay of treatment for acute uncomplicated appendicitis. Published in the Annals of Surgery and led by researchers from the RCSI…
Of mice and men and their different tolerance to pathogens
A mouse intestine-on-chip discovery platform enables the modeling of host-microbiome relations, infectious disease modeling, and the identification of tolerance-promoting species
CT colonography most effective noninvasive colorectal cancer screening test
Compared with multi-target stool-DNA and fecal immunochemical test, CT colonography with 10 mm threshold most effectively targets advanced neoplasia–preserving detection while decreasing unnecessary colonoscopies
Cleveland Clinic researchers discover microbial infection that impairs healing in Crohn’s disease
Study published in Science lays the groundwork for new strategies to treat or prevent the disease
Probiotics increase gut bacteria diversity in extremely preterm infants
Extremely preterm infants can suffer from a life-threatening inflammation of the gut. A new clinical study has shown that supplements of a lactic acid bacterium may have positive effects by increasing the diversity of intestinal bacteria in these infants. The…
Foodborne fungus impairs intestinal wound healing in Crohn’s disease
Study in mice, people suggests new approaches to treating symptoms
Scientists report gastrointestinal manifestations and mechanisms of COVID-19
Recently, Prof. ZHU Shu from University of Science and Technology of China (USTC) of CAS and Prof. Richard A. Flavell from Yale University were invited to publish a review article in Nature Reviews Gastroenterology and Hepatology.
Microbes may hold the key for treating neurological disorders
When we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the best or only way? Maybe not. New research by scientists at Baylor College of Medicine suggests…
Therapy Sneaks into Hard Layer of Pancreatic Cancer Tumor and Destroys it From Within
Researchers at University of California San Diego School of Medicine and Moores Cancer Center demonstrated that a new tumor-penetrating therapy could enhance the effects of chemotherapy, reduce the spread of pancreatic cancer and increase survival in animal models.
March Special Issue of The American Journal of Gastroenterology Focuses on Women’s Health in Gastroenterology and Hepatology
The March issue of The American Journal of Gastroenterology features new clinical research involving sex and gender, including effects of GI and liver conditions on pregnancy, gender disparities in diet and nutrition, Barrett’s esophagus incidence in women with scleroderma, factors influencing whether women pursue advanced endoscopy careers, endoscopy-related musculoskeletal injuries, sex hormone association with increased prevalence of certain types of cancer, and more.
FDA qualifies C-Path’s Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C)
TUCSON, Ariz., March 9, 2021 — Critical Path Institute’s (C-Path) Patient-Reported Outcome (PRO) Consortium announces the qualification of the Diary for Irritable Bowel Syndrome Symptoms-Constipation (DIBSS-C) by the U.S. Food and Drug Administration (FDA). The DIBSS-C was developed by the…
Characterizing different cell types in the upper gastrointestinal tract
Researchers from the group of Hans Clevers identified and characterized rare cell types in the upper gastrointestinal tract. Using single cell RNA sequencing, they studied the cellular composition of the esophagus, stomach and upper part of the small intestine. They…
The gut mycobiome influences the metabolism of processed foods
New research in mice points to a significant role for fungi to shape metabolism, including fat deposition, and metabolic hormones.
Controlling adhesions in the abdomen
Scars inside the abdomen, known as adhesions, form after inflammation or surgery. They can cause chronic pain and digestive problems, lead to infertility in women, or even have potentially life-threatening consequences such as intestinal obstruction. If adhesions develop, they must…