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UrduUntil recently, it was believed that human urine is sterile, but advanced culturing techniques and DNA sequencing have revealed that bacteria and other microbes – such as viruses and fungi – inhabit the human bladder and urinary tract, known collectively as the “urobiome.” Now in study that is one of the first of its kind, Dr.
Tag: Dna Sequencing
Scientists pinpoint the microbes essential to making traditional mozzarella
Scientists from Italy used high-throughput 16S rRNA amplicon sequencing, which gives a detailed picture of what microbes are present and in what proportions, to understand how microbes make mozzarella.
New Resource Harmonizes 16S and Shotgun Sequencing Data for Microbiome Research
UC San Diego scientists debut Greengenes2, a massive reference database that could be used to reconcile years of microbiome studies.
The Alliance for Genomic Discovery announces founding biopharma members: AbbVie, Amgen, AstraZeneca, Bayer and Merck
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, today announced the five founding new members of the Alliance for Genomic Discovery (AGD).
Extreme DNA resolution: Researchers slow down and scan multiple times individual DNA molecules
Aleksandra Radenovic, head of the Laboratory of Nanoscale Biology in the School of Engineering, has worked for years to improve nanopore technology, which involves passing a molecule like DNA through a tiny pore in a membrane to measure an ionic current.
High-throughput experiments might ensure a better diagnosis of hereditary diseases
Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.
Do all fungi matter? Yes, new study argues
Mention fungi, and most people will probably think of the mushrooms they pick in fall, or maybe the yeast they add when baking or making wine. Others will perhaps recall last week’s mouldy bread – or cucumbers gone bad in the refrigerator. Indeed, mycologists have studied these fungi as sources of food and fermentation but also decay and disease for centuries.
UNLV Study Sheds Light on Ancient Microbial Dark Matter
Omnitrophota are nano-sized bacteria first discovered 25 years ago. Though common in many environments around the world, until now they’ve been poorly understood. An international research team produced the first large-scale analysis of Omnitrophota genomes, uncovering new details about their biology and behavior. The team’s findings are reported in the March 16 issue of the journal Nature Microbiology.
Even good gene edits can go bad
A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.
Global Experts Introduce Strategic Action Plan to Accelerate Patient Access to Next-Generation DNA Sequencing in Oncology
Value & Outcomes Spotlight, the health economics and outcomes research (HEOR) news magazine of ISPOR—The Professional Society for Health Economics and Outcomes Research, announced the publication of a supplement, “A Plan of Action: Accelerating Patient Access to Next-Generation Sequencing in Oncology.”
Genotyping Reveals Significance of Mesophotic Reefs for Florida Keys’ Coral Recovery
Researchers are the first to compare the genetic structure and genomic diversity of paired shallow and upper mesophotic coral sites in the Northern and Southern Dry Tortugas and the Lower and Upper Florida Keys. Results suggest that while vertical connectivity between paired shallow and mesophotic populations can vary, certain mesophotic coral populations are important for maintaining the long-term survival of this ecologically important coral species throughout the Florida Keys and should be considered in future management strategies.
Leading Scientist Working to Complete the Human Genome to Join UCSC Faculty
Leading scientist known for working to complete the human genome will join UCSC faculty; Karen Miga is a longtime Genomics Institute researcher, recently named “one to watch” by the journal Nature.
Overfishing of Atlantic Cod Likely Did Not Cause Genetic Changes
Overfishing likely did not cause the Atlantic cod, an iconic species, to evolve genetically and mature earlier, according to a study led by Rutgers University and the University of Oslo – the first of its kind – with major implications for ocean conservation.
New sequencing approach finds triple-negative breast cancers continue accumulating genetic changes during tumor growth
A new DNA sequencing approach developed by MD Anderson researchers overcomes technical challenges with earlier techniques to give deeper insights into breast cancer evolution.
Lab shutdowns enable speedier investigation of coral disease
Research labs have shut down around the world due to the COVID-19 pandemic, but that hasn’t stopped scientists from Woods Hole Oceanographic Institution (WHOI) from investigating critical problems in the ocean.
Small Mutations Identified through Deep DNA Sequencing for AML and MDS
Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations. These may help further guide treatment decision making for patients.
NEW TWIST ON CRISPR TECHNOLOGY
Researchers at the University of Delaware, using the revolutionary new genetic technology known as CRISPR/Cas9 have found a way to improve the efficiency and precision of the way enzymes work together to produce certain biochemical reactions in cells. Their new application essentially creates a dynamic assembly line that can lead to advances in pharmaceuticals, agriculture and biofuels.