The latest World Health Organization’s Global Tuberculosis Report released in November 2024 painted a sobering picture; approximately 8.2 million people were newly diagnosed with TB in 2023, the highest number since the organization began global TB monitoring in 1995. TB is the leading cause of death among those with HIV /AIDS worldwide. According to the WHO, in 2023, 161,000 people died of HIV-associated TB.
Tag: TB
Researchers Reveal Why a Key Tuberculosis Drug Works Against Resistant Strains
Rutgers Health study uncovers vulnerabilities in drug-resistant TB, offering hope for improved treatments.
Houston Methodist Tuberculosis expert Ed Graviss says U.S. experiencing its highest number of TB cases in 10 years
With tuberculosis (TB) experiencing a resurgence as the top infectious disease killer globally and resulting in roughly 1.25 million deaths last year, the world is seeing its highest number of TB cases recorded in the nearly three decades since the…
Bird Flu Basics: Safety, Symptoms and Risks
The highly infectious bird flu, also known as avian influenza H5N1, primarily spreads among birds. However, there have been rare cases of infection to humans. According to the Centers for Disease Control and Prevention, two human cases of H5N1 have…
More than 18,000 excess TB cases in the U.S. attributable to structural racism
A robust analysis of national tuberculosis (TB) surveillance data found continuing, persistent disparities in TB incidence among U.S.-born racial and ethnic minorities, despite an overall decrease in cases observed during the analysis period.
Measles: How to Spot it, When to Seek Care and Importance of Vaccination
As the Measles outbreak continues to grow in Florida, Francesca Torriani, MD, infectious disease specialist with UC San Diego Health is available to discuss symptoms to look out for, when to seek medical care, and the importance of vaccination. Biography…
Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains
Johns Hopkins Medicine investigators say their research indicates a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant (MDR) strains
Diversifying the next generation of TB vaccines
NIH’s National Institute of Allergy and Infectious Diseases awarded Texas Biomedical Research Institute and The Access to Advanced Health Institute in Seattle, Washington, a $3.5 million, five-year Innovation for Tuberculosis Vaccine Discovery grant.
Hackensack Meridian CDI Scientists Awarded NIH Grant for $6.4 Million to Pursue TB Vaccine
Focus of the work is bolstering B-cell immunity to help body beat bacteria
Hackensack Meridian CDI Scientists Discover New Tuberculosis Treatment Pathway
The compound TA-C is metabolized by TB bacteria – weakening the germ from within like a ‘Trojan horse’ attack
Friend or foe? Seeliger probes the mysteries of mycobacteria
From studies in her lab at Stony Brook University in New York to private-sector collaborations, Hertz Fellow Jessica Seeliger is accelerating the fight against multiple deadly diseases.
Global Respiratory Groups Join WHO, Calling On World Leaders to Act On the Commitments Made to End TB
In support of World TB Day, March 24, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, joins the World Health Organization campaign urging governments to act on the commitments made to end TB.
Study Identifies Concerning Delays in TB Diagnoses in the United States
Most delays ranged between 10 and 45 days, with a median of 24 days, after a visit to a doctor, which exceeds current World Health Organization recommendations of diagnosing and treating TB within two to three weeks of symptom onset
Delays were linked to greater risk for disease complications, transmission of infection to household members
Older individuals and those with compromised immunity were at greater risk for delayed diagnoses
Use of diagnostic molecular testing, use of chest imaging and being seen by a specialist were all linked to more prompt identification of TB infection, suggesting delays may be preventable
Findings underscore the need to increase awareness of TB among frontline clinicians who may not suspect TB due to rarity of infection in this country
To Meet HIV World Health Goals, TB Treatment Must be Maintained During COVID-19 Response
This World AIDS Day, the Forum of International Respiratory Societies (FIRS), of which the ATS is a founding member, is calling on governments, health advocates and non-government organizations to strengthen their response to AIDS and tuberculosis, and to ensure that TB services are maintained throughout their response to COVID-19.
Rutgers Researchers Awarded $20 Million NIH Grant to Find New Ways to Diagnose Tuberculosis
Rutgers researchers have been awarded a $20 million grant by the National Institutes of Health (NIH) to evaluate new point of care tests that would diagnose Tuberculosis, the number one cause of deaths worldwide due to an infectious disease.
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Within a month following a heart attack, people are at increased risk for a second one. As a result, physicians treat these patients with medications to rapidly reduce cardiovascular risk factors for another event. Although statins are designed to reduce the risk from one underlying problem, low-density lipoprotein (LDL) or “bad” cholesterol, they often aren’t able drop it to recommended levels within 30 days. Now, testing a next-generation cholesterol-lowering drug known as a PCSK9 inhibitor, Johns Hopkins Medicine researchers showed they could lower blood cholesterol to safer levels faster when it is added to traditional therapies.
Forum of International Respiratory Societies Calls to Advance Prevention as Critical Strategy to End TB
In support of World TB Day, 24 March, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, urges governments to promote tuberculosis prevention as a critical component of TB elimination.
Immune responses to tuberculosis mapped across 3 species
A new study led by Washington University School of Medicine in St. Louis offers a genetic road map detailing the similarities and differences in immune responses to TB across three species — mice, macaques and humans. According to the researchers, the insight into the immune pathways that are activated in diverse models of TB infection will serve as a valuable tool for scientists studying and working to eradicate the disease.
Delivering TB Vaccine Intravenously Dramatically Improves Potency, Study Shows
Worldwide, more people die from tuberculosis than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn’t that reliable. But a new Nature study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.
To Meet HIV World Health Goals, TB Must Also Be Reduced
The World Health Organization has set a goal of ending the AIDS epidemic by 2030.
Collaboration with Texas Biomed, SwRI and UT Health San Antonio targets Bladder Cancer
The San Antonio Medical Foundation (SAMF) has awarded Texas Biomedical Research Institute Professor Jordi B. Torrelles, Ph.D., with a $173,000 grant to study a modified Mycobacterium bovis Bacillus Calmette et Guérin (BCG) vaccine shown to have promise for treating bladder cancer. BCG is a weakened strain of Mycobacterium bovis, a vaccine for tuberculosis.
Tuberculous Infection Is Not Life-Long in Most People
A new analysis challenges the longstanding notion that tuberculous infection is a life-long infection that could strike at any time and cause tuberculosis
Despite Progress, TB Remains the Leading Global Infectious Killer: WHO Report
Following today’s release of the World Health Organization’s Global Tuberculosis Report 2019, the American Thoracic Society joins the WHO in calling for redoubled efforts to end the global TB pandemic by 2030, the goal set by the global community in the United Nations Political Declaration to End Tuberculosis on Sept. 26, 2018.
Lung Lining Fluid Key to Elderly Susceptibility to Tuberculosis Disease
– Old lungs are not as capable as young lungs of fighting off an infection of the bacteria that causes tuberculosis (TB), placing seniors at a greater risk of developing TB. The microbe that causes this infectious disease, Mycobacterium tuberculosis (Mtb), currently kills more people in the world than any other pathogen. Texas Biomed researchers published an article in the Journal of Infectious Diseases in July 2019. The study details an experiment that took place in vitro (in the lab) and in vivo (in animals) that showed fluid in the lining of the lungs plays a big role in the elderly’s susceptibility to infection with the bacterium Mtb.
UIC’s Institute for Tuberculosis Research tapped to support $28 million drug discovery project
The University of Illinois at Chicago will work with TB Alliance to help find new drug treatments for tuberculosis, a bacterial infection considered to be one of the leading causes of death worldwide. TB Alliance is a nonprofit organization dedicated…