Understanding how antibodies and antibody-secreting cells can fight against lung infection will provide new directions for improving vaccines to prevent severe respiratory infection and for designing treatments that cure respiratory infections
Tag: PULMONARY/RESPIRATORY MEDICINE
Vitamin D may not provide protection from COVID-19 susceptibility or disease severity
Observational studies have suggested that increased vitamin D levels may protect against COVID-19. However, these studies were inconclusive and possibly subject to confounding. A study published in PLOS Medicine by Guillaume Butler-Laporte and Tomoko Nakanishi at McGill University in Quebec,…
Air quality improved during India lockdown, study shows
Research by scientists from University of Southampton (UK) and the Central University of Jharkhand (India) and has shown the first COVID-19 lockdown in India led to an improvement in air quality and a reduction in land surface temperature in major…
Policy changes urgently needed to support tobacco cessation, warn respiratory groups
On World No Tobacco Day (31 May, 2021) the Forum of International Respiratory Societies (FIRS), of which the American College of Chest Physicians® (CHEST) is a founding member, calls on governments and policymakers to make greater political and financial commitments…
Assessment of SARS-CoV-2 reinfection 1 year after primary infection in Lombardy, Italy
What The Study Did: Study r esults suggest that reinfections are rare events and that patients who have recovered from COVID-19 have a lower risk of reinfection. However, the observation ended before SARS-CoV-2 variants began to spread, and it is…
SARS-CoV-2 antibody status in patients with cancer, health care workers
What The Study Did: This study evaluates whether there are differences in SARS-CoV-2 seroprevalence and antibody levels in patients with cancer compared with health care workers in Japan. Authors: Tatsuya Yoshida, M.D., Ph.D., of the National Cancer Center Hospital in…
Social connectedness among medicare beneficiaries after onset of pandemic
What The Study Did: Researchers examined social connectedness among Medicare beneficiaries during the COVID-19 pandemic. Authors: Wesley John Talcott, M.D., M.B.A., the Yale School of Medicine in New Haven, Connecticut, is the corresponding author. To access the embargoed study: Visit…
Socioeconomic disparities in respiratory health in US
What The Study Did: Socioeconomic disparities in respiratory health over the past six decades in the United States are described in this study. Authors: Adam W. Gaffney, M.D., of the Cambridge Health Alliance in Cambridge, Massachusetts, is the corresponding author.…
Seropositivity following mRNA vaccination for SARS-CoV-2 in patients undergoing cancer treatment
What The Study Did: R ates of antispike antibody response to a messenger RNA SARS-CoV-2 vaccine in Israeli patients with cancer who are undergoing systemic treatment compared with healthy controls were evaluated in this study. Authors: Salomon M. Stemmer, M.D.,…
Helping doctors manage COVID-19
New tool uses AI technology to assess the severity of lung infections and inform treatment
Rheumatoid arthritis and systemic lupus erythematosus during COVID-19 quarantine period
The article by Dr. Michael L. Tee and colleagues is published in The Open Rheumatology Journal, 2021
FAPESP will discuss an integrative approach to clinical long-term effects of COVID-19
Renowned scientists sharing their research and clinical practice will take part at the webinar. They will tackle the patients’ evolving clinical conditions and the challenges of dealing with the subacute phase.
Association of tracheostomy with outcomes in patients with COVID-19 and SARS-CoV-2 transmission among health care workers
What The Study Did: The findings of this systematic review and meta-analysis indicate that enhanced personal protective equipment is associated with low rates of SARS-CoV-2 transmission during tracheostomy. Authors: Phillip Staibano, M.Sc., M.D., of McMaster University in Ontario, Canada, is…
Myocarditis in big ten athletes with recent SARS-CoV-2 infection
What The Study Did: In this study of 1,597 Big Ten athletes who had comprehensive cardiac screening, including cardiac magnetic resonance (CMR) imaging, after COVID-19 infection, 37 athletes (2.3%) were diagnosed with clinical and subclinical myocarditis. Researchers report CMR screening…
AI with swarm intelligence
A novel technology for cooperative analysis of big data
Accessibility, usability of state health department COVID-19 vaccine websites
What The Study Did: Researchers analyzed each state’s department of health website for accessibility and usability challenges. Findings suggest s tate health department COVID-19 vaccine website accessibility and usability challenges create frustration, may promote health disparities and contribute to overall…
Frequency, variety of persistent symptoms among patients with COVID-19
What The Study Did: Researchers conducted a r eview of studies examining the frequency and variety of persistent symptoms after COVID-19 infection. Authors: Steven N. Goodman, M.D., M.H.S., Ph.D., of Stanford University in Stanford, California, is the cor responding author.…
Measuring opioid-related mortality in Canada during COVID-19 pandemic
What The Study Did: Researchers quantified the added burden of fatal opioid overdoses occurring in Ontario, Canada, during the first six months of the COVID-19 pandemic. Authors: Tara Gomes, Ph.D., of the Keenan Research Centre of the Li Ka Shing…
Overdose-associated cardiac arrests during COVID-19 pandemic
What The Study Did: T his study included data from more than 11,000 emergency medical services (EMS) agencies in 49 states to describe racial/ethnic, social and geographic changes in EMS-observed overdose-associated cardiac arrests during the COVID-19 pandemic through 2020 in…
Ultra-low doses of inhaled nanobodies effective against COVID-19 in hamsters
PITTSBURGH, May 26, 2021 – In a paper published today in Science Advances , researchers from the University of Pittsburgh School of Medicine showed that inhalable nanobodies targeting the spike protein of the SARS-CoV-2 coronavirus can prevent and treat severe…
ATS/Mallinckrodt Research Grant on COVID-19 in underrepresented minorities awarded
(New York, NY) – May 25, 2021 – Neelima Navuluri, MD, of Duke University has been awarded the ATS/Mallinckrodt Research Grant on COVID-19 in Underrepresented Minorities. The $50,000 award will help fund Dr. Navuluri’s research study, “Prospective Study of Racial…
New AI technology protects privacy
Medical diagnostics algorithm identifies pneumonia in paediatric x-ray images
Association between bitter taste receptor types, clinical outcomes among patients with COVID-19
What The Study Did: This study evaluates the association between bitter taste receptor types (supertasters who experience greater intensity of bitter tastes ; tasters; and nontasters who experience low intensity of bitter tastes or no bitter tastes) and outcomes after…
Association of circulating sex hormones with COVID-19 severity
What The Study Did: Researchers examined if circulating sex hormones are associated with disease severity in patients with COVID-19. Authors: Sandeep Dhindsa, M.D., of the St Louis University School of Medicine and Abhinav Diwan, M.D., of the Washington University School…
U of M Medical School receives $1.5M for nation’s first ivermectin COVID-19 clinical trial
An expansion of an ongoing outpatient clinical trial, the study now includes metformin, fluvoxamine and ivermectin as possible treatments of COVID-19 and to prevent “long COVID”
COVID-19 mortality associated with 2 signs easily measured at home
Abnormal blood-oxygen levels and breathing rates are strong predictors of poor patient outcomes in-hospital, study shows
Autonomous cortisol secretion associated with 2- to 3-fold increase in mortality risk
Embargoed news from Annals of Internal Medicine
Effectiveness of tocilizumab in patients hospitalized with COVID-19
What The Study Did: This follow-up study of a randomized clinical trial examines the association between survival and C-reactive protein levels in patients hospitalized with COVID-19 who were treated with tocilizumab. Authors: Xavier Mariette, M.D., Ph.D., of the Hôpital Bicêtre…
Socioeconomic, racial inequities in breast cancer screening during pandemic in Washington state
What The Study Did: Researchers used clinical data to examine differences in breast cancer screenings before and during the COVID-19 pandemic overall and among sociodemographic groups. Data included completed screening mammograms within a large statewide nonprofit community health care system…
In utero exposure to tiny air pollution particles is linked to asthma in preschoolers
Mount Sinai researchers are first to find ultrafine particles from traffic pollution influences asthma risk in US children
Examining variation in SARS-CoV-2 infection risk, socioeconomic disadvantage in Mayan-Latinx population
What The Study Did: V ariation in SARS-CoV-2 infection risk and socioeconomic disadvantage among a Mayan-Latinx population in Fruitvale, California, was examined in this study. Authors: Paul Wesson, Ph.D., of the University of California, San Francisco, is the corresponding author.…
Medication use in hospitalized patients with COVID-19
What The Study Did: M edication use among hospitalized patients for COVID-19-related treatment in a large university health care system was examined in this study. Authors: Jonathan H. Watanabe, Pharm.D., Ph.D., of the University of California, Irvine, School of Pharmacy…
Preliminary analysis of association between COVID-19 vaccination, sudden hearing loss
What The Study Did: These prelimi nary findings using U.S. Centers for Disease Control and Prevention Vaccine Adverse Events Reporting System data in the early phase of societal COVID-19 vaccination using two messenger RNA vaccines sug gest that no association…
Coronavirus transmission in Queens drove the first wave of New York city’s pandemic
The most populous boroughs in New York City, Queens and Brooklyn, likely served as the major hub of COVID-19 spread in the spring of 2020, a new study finds. Led by researchers at NYU Grossman School of Medicine, the new…
New research maps COVID-19 dispersal dynamics in New York’s first wave of epidemic
Study suggests borough of Queens was major hub of COVID-19 dispersal
VOYAGE phase 3: Dupilumab significantly reduced asthma exacerbations in children age 6-11
ATS 2021, New York, NY – Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS…
Assessing association of vitamin D level with SARS-CoV-2 seropositivity among working-age adults
What The Study Did: SARS-CoV-2 seropositivity wasn’t associated with low levels of vitamin D independently of other risk factors. Authors: Yonghong Li, Ph.D., of Quest Diagnostics in San Juan Capistrano, California, is the corresponding author. To access the embargoed study:…
Characteristics associated with multisystem inflammatory syndrome among adults with SARS-CoV-2
What The Study Did: C linical characteristics and outcomes of patients with multisystem inflammatory syndrome among adults with laboratory-confirmed SARS-CoV-2 infection at a single U.S. medical center are described in this study. Authors: Giovanni E. Davogustto, M.D., of the V…
Consumer views on using digital data for COVID-19 control
What The Study Did: This study looked at the use of consumer digital information for COVID-19 control U.S. adults consider to be acceptable and the factors associated with higher or lower approval of using this information. Authors: David Grande, M.D.,…
Breast cancer treatments do not increase risk of Covid-19 infection or death
Cancer drugs capable of weakening the body’s immune defenses are no more likely to increase the risk of Covid-19 infection or death than breast cancer therapies that do not undermine the immune system, a new study shows. Researchers say the…
UB pharmacy researcher to develop real-time algorithm to lower hospital readmission rates
Project funded by career development award for David Jacobs seeks to help patients with COPD
Lockdowns may affect children’s fitness — Study
Research finds normal cardiorespiratory development in adolescents is delayed
Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial
ATS 2021, New York, NY – Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to…
AI predicts lung cancer risk
OAK BROOK, Ill. – An artificial intelligence (AI) program accurately predicts the risk that lung nodules detected on screening CT will become cancerous, according to a study published in the journal Radiology . Lung cancer is the leading cause of…
Secondhand tobacco exposure in utero linked to decreased lung function in children
ATS 2021, New York, NY – Environmental tobacco smoke exposure in utero and during early childhood–especially secondhand smoke–is associated with decreased childhood lung function, according to research presented at the ATS 2021 International Conference. Hanna Knihtilä, MD, PhD, research fellow,…
Two-fifths of US seniors with COPD have poor access to pulmonary rehabilitation
ATS 2021, New York, NY – Approximately two-fifths of Medicare beneficiaries with chronic obstructive pulmonary disease (COPD) have limited access to pulmonary rehabilitation services due to their distance from rehab centers, according to research presented at the ATS 2021 International…
Community factors associated with telemedicine use during COVID-19 pandemic
What The Study Did: T elemedicine use grew rapidly during the COVID-19 pandemic but there was geographic variation in its use so researchers in this study examined the association of county-level telemedicine use with community factors among people with commercial…
Nanofiber filter captures almost 100% of coronavirus aerosols
The filter could help curb airborne spread of COVID-19 virus
Health outcomes differ between UK and US children with cystic fibrosis
A new study led by University of Liverpool researchers has confirmed that children with cystic fibrosis (CF) in the US have better lung function than UK children with the disease.
Asthma attacks plummeted among Black and hispanic/latinx individuals during the COVID-19 pandemic
Asthma attacks account for almost 50 percent of the cost of asthma care which totals $80 billion each year in the United States