The central nervous system (CNS) is the most vital component of our body, regulating various kinds of daily activities that are essential for our life processes. Keeping the balance between body and brain and maintaining the homeostasis of CNS is…
Tag: Parkinson’s Disease
Low blood flow in the brain may be an early sign of Parkinson’s disease
Patients who suffer from REM sleep behaviour disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue.
Impaired dopamine transporters contribute to Parkinson’s disease-like symptoms
A rare mutation that causes Parkinson’s disease-like symptoms interrupts the flow of dopamine in the brain, suggests a study in fruit flies published today in eLife.
Low blood flow in the brain may be an early sign of Parkinson’s disease
Patients who suffer from REM sleep behaviour disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue. In the long term, this may cause symptoms of Parkinson’s disease.
Impaired dopamine transporters contribute to Parkinson’s disease-like symptoms
A rare mutation that causes a Parkinson’s disease-like disorder in young children interferes with dopamine transporters in the brain, suggesting that treatments targeting the transporters may be beneficial.
American College of Sports Medicine and Parkinson’s Foundation Announce Exercise Recommendations for Parkinson’s Disease
ACSM and the Parkinson’s Foundation released new exercise recommendations to provide safe and effective guidance on physical activity to people with Parkinson’s and to certified exercise professionals working with them.
Step-closer to nasal spray drug delivery for Parkinson’s disease
Scientists at the University of York have made significant progress in the development of a nasal spray treatment for patients with Parkinson’s disease. Researchers have developed a new gel that can adhere to tissue inside the nose alongside the drug…
Parkinson’s patients are particularly affected by COVID-19
A reason for these findings could be due to the fact that Parkinson’s patients often also have many risk factors for a severe course of Covid-19.
Parkinson’s patients are particularly affected by COVID-19
Healthcare research
Protein simulation, experiments unveil clues on origins of Parkinson’s disease
HERSHEY, Pa. — Parkinson’s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew…
Fresh insight into protein production inside brain cells could help tackle Parkinson’s
Wednesday 19 May 2021 – New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.…
New insight into protein production in brain could help tackle dementia
Peer-reviewed | experimental study | animals and cells
Scientists find small molecule cocktail to improve stem cell use in research, medicine
Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function. The researchers suggest that the…
Researchers wirelessly record human brain activity during normal life activities
NIH BRAIN Initiative-funded study opens the door to correlating deep brain activity and behavior
Awakening ‘ghosts’ in patients with Parkinson’s, a powerful diagnostic tool
“We’re developing something similar to a cardiac stress test, but instead of testing the heart, we’re testing the brain,” says EPFL neuroscientist Olaf Blanke. EPFL scientists are providing a new way to evaluate the onset of hallucinations in patients with…
Study says inflammation seen in earliest stages of Parkinson’s disease, and it is different between men and women
New research shows evidence of inflammation in the blood of Parkinson’s disease patients during the earliest stages of the disease, lending support to theories that inflammation is a major driver of PD. The study also points out differences between the sexes in the symptoms and course of the disease.
What Parkinson’s Disease Patients Reveal About How Art is Experienced and Valued
Altered neural functioning, like that experienced in patients with Parkinson’s disease, changes the way art is both perceived and valued. People with neurological motor dysfunction demonstrated decreased experiences of motion in abstract art and enhanced preferences for high-motion art, compared to a healthy control group.
April 2021: Parkinson’s Disease Awareness Month: Expert Available To Discuss Research
Parkinson’s disease (PD) is a neurodegenerative movement disorder that affects predominantly dopamine-producing (“dopaminergic”) neurons in a specific area of the brain called substantia nigra. April has been designated Parkinson’s Disease Awareness Month and research expert Professor Markus Riessland from Stony…
ACS Spring 2021 press conference schedule
Watch live and recorded press conferences at http://www. acs. org/ acsspring2021conferences . Press conferences will be held Monday, April 5, through Friday, April 16, 2021. Below is the schedule, which will be updated as needed. ALL TOPICS ARE STRICTLY EMBARGOED…
Protein Linked to ALS/Ataxia Could Play Key Role in Other Neurodegenerative Disorders
A new study suggests that some neurological disorders share a common underlying thread. Staufen1, a protein that accumulates in the brains of patients with certain neurological conditions, is linked to amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, along with other neurological disorders, including Alzheimer’s, Parkinson’s, and Huntington’s disease, according to University of Utah Health scientists.
FSU College of Medicine research links Parkinson’s disease and neuroticism
New research from the Florida State University College of Medicine has found that the personality trait neuroticism is consistently associated with a higher risk of developing the brain disorder Parkinson’s disease.
The research by Professor of Geriatrics Antonio Terracciano and team, published in Movement Disorders, found that adults in the study who scored in the top quartile of neuroticism had more than 80% greater risk of Parkinson’s, compared to those who scored lower on neuroticism.
Researchers receive funding to help Parkinson’s patients, protect environment
BINGHAMTON, N.Y. — New grants from the State University of New York could help researchers at Binghamton University create a new therapy to provide relief to Parkinson’s patients and help locate abandoned oil and gas wells. Binghamton University researchers Christopher…
An amyloid link between Parkinson’s disease and melanoma
WASHINGTON, April 7, 2021 — On the surface, Parkinson’s disease — a neurodegenerative disorder — and melanoma — a type of skin cancer — do not appear to have much in common. However, for nearly 50 years, doctors have recognized…
Unraveling the mysteries of sleep disorders in multiple system atrophy
New study shows that in multiple system atrophy, sleep disorders are a common but scarcely studied symptom associated with disease severity
Study shows why crossing obstacles is difficult for patients with Parkinson’s disease
The scientists detected incapacities related to gait timing and foot placement. Their discoveries serve as a basis for the development of an exercise protocol that mitigates the difficulty.
New Blueprint of Brain Connections Reveals Extensive Reach of Central Regulator
Scientists have created a connectivity map from a brain hub that regulates motor and behavior functions. The connections could open avenues for intervention of Parkinson’s disease and other disorders such as Tourette’s syndrome, ADHD and obsessive-compulsive disorder.
Distinct Parkinson’s Disease Symptoms Tied to Different Brain Pathways
Neurobiologists have found that identifiable brain pathways are linked with specific debilitating symptoms of Parkinson’s disease. The findings could help form the basis for improving therapeutic strategies for precise symptoms of Parkinson’s at various levels of disease progression.
Exercise May Help Slow Cognitive Decline in Some People with Parkinson’s Disease
For people with Parkinson’s disease, problems with thinking and memory skills are among the most common nonmotor symptoms of the disease. A new study shows that exercise may help slow cognitive decline for some people with the disease. The study is published in the March 31, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Exercise may help slow cognitive decline in some people with Parkinson’s disease
MINNEAPOLIS – For people with Parkinson’s disease, problems with thinking and memory skills are among the most common nonmotor symptoms of the disease. A new study shows that exercise may help slow cognitive decline for some people with the disease.…
Experimental antibodies for Parkinson’s, Alzheimer’s may cause harmful inflammation
Scientists find evidence that antibody-based treatments in clinical trials for neurodegenerative diseases may trigger an inflammatory response in human brain immune cells, eroding their positive effects.
Funding research toward treating the root cause of neurodegenerative disease
Professor and GlycoNet Investigator Simonetta Sipione’s research awarded major grant from the Canadian Institutes of Health Research
Parkinson’s gene may impair how new neurons are made throughout our lifetime
A pioneering study, published in Scientific Reports, found that the Parkinon’s gene PINK1 is important for the generation of dopamine-producing neurons throughout life, and is not just responsible for the premature death of these neurons.
Parkinson’s gene may impair how new neurons are made throughout our lifetime
A pioneering study, published in Scientific Reports , found that the Parkinon’s gene PINK1 is important for the generation of dopamine-producing neurons throughout life, and is not just responsible for the premature death of these neurons The international research, led…
Cholesterol accumulation contributes to genetic movement disorder
Family finds hope in research breakthrough for rare diagnosis
Scientists identify genetic pathway that suppresses Lou Gehrig’s Disease
Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS). Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and…
Parkinson’s disease: When molecular guardians need to be protected
Parkinson’s disease is the second most common, age-related, neurodegenerative disease: In Germany alone, about 300,000 people are affected and experience sometimes major limitations to their quality of life. Although Parkinson’s is so widespread, there is still no treatment that targets…
Screening for drugs against brain diseases with novel technology
Drug testing with 3D cell cultures
Identifying cells to better understand healthy and diseased behavior
Graphical model an advance in common neuroscience bottleneck
At face value: Using facial analysis algorithm to track changes due to Parkinson’s disease
Scientists showcase how AI-based software can reveal trends in facial changes caused by neurological disorders
Researchers discover how the brain learns from subconscious stimuli
Researchers uncovered for the first time what happens in animals’ brains when they learn from subconscious, visual stimuli. In time, this knowledge can lead to new treatments for a number of conditions. The study, a collaboration between KU Leuven, Massachusetts…
Crucial step in formation of deadly brain diseases discovered
For the first time, researchers have pinpointed what causes normal proteins to convert to a diseased form, causing conditions like CJD and Kuru
Saarbrücken based bioinformaticians trace down molecular signals of Parkinson’s disease
In their study, which is now published in the journal Nature Aging , they show that the level of non-coding RNAs in the blood of a Parkinson’s patient can be used to track the course of the disease. For their…
Scientists move closer to developing ‘game-changing’ test to diagnose Parkinson’s
Results published today show it is possible to identify Parkinson’s based on compounds found on the surface of skin.
Scientists move closer to developing ‘game-changing’ test to diagnose Parkinson’s
Results published today show it is possible to identify Parkinson’s based on compounds found on the surface of skin. The findings offer hope that a pioneering new test could be developed to diagnose the degenerative condition through a simple and…
Demystifying the ‘Parkinson Protein’
Research team led by the physical chemist Professor Malte Drescher from Konstanz succeeds in directly observing the membrane binding of α-synuclein in living cells
Convincing evidence that type 2 diabetes is associated with increased risk of Parkinson’s
Research from Queen Mary University of London has concluded that type 2 diabetes is associated with an increased risk of Parkinson’s disease and that type 2 diabetes may contribute to faster disease progression in patients with Parkinson’s
Immune cells in blood influence the brain during early development of Parkinson’s disease
A group of people with sleep disorders have helped researchers from Aarhus make an important discovery about Parkinson’s disease. The study could pave the way for new diagnostic tools and forms of treatment in the future
Smoking cessation drug may treat Parkinson’s in women
Texas A&M researchers have found that that cytisine can reduce dopamine neuron loss, providing a protective effect against the neurodegenerative disorder.
Get into the Swing: Golf May Have More Benefit for Parkinson’s than Tai Chi
When it comes to exercise that does the most good for people with Parkinson’s disease, golf may hit above par when compared to tai chi. That’s according to a preliminary study released today, March 3, 2021, that will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 to April 22, 2021. The study found that golf was better than tai chi for improving balance and mobility.
Sesaminol: Parkinson’s disease’s surprise medicine
Osaka City University shows that sesaminol, purified from industrial sesame seed by-product, can help prevent Parkinson’s disease.