English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduA team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), led by Assistant Professor Anand Jeyasekharan, has discovered a unique combination of oncogenes that could predict treatment resistance, and hence unfavourable outcomes, of patients with Diffuse large B cell lymphoma (DLBCL), the most common type of blood cancer in Singapore and globally.
Tag: Oncogene
Research provides evidence for how a key transcription factor manages access to DNA
St. Jude Children’s Research Hospital scientists have revealed a previously unknown role for CTCF, a pivotal transcription regulator linked to cancer.
Retinoblastoma resource: Researchers create more accurate research model
St. Jude Children’s Research Hospital scientists have created a model of the rare pediatric eye cancer that more closely mimics the biology of patient tumors.
Tumor cell PD-L1 may mediate sensitivity to chemotherapy in colorectal cancer treatment
Data in a study by Mayo Clinic Cancer Center researchers indicates that the level of tumor cell PD-L1, a protein that acts as a brake to keep the body’s immune responses under control, may be an important factor for sensitivity to chemotherapy in colorectal cancer treatment. The study was published Friday, July 2, in Oncogene.
Mount Sinai Researchers Discover a Novel Class of Drugs That May Help Treat a Deadly Type of Lymphoma
A new class of drugs that inhibits a “master switch” involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin’s lymphoma, has been discovered by researchers at Mount Sinai.
Potential Target for Treating Many Cancers Found Within GLI1 Gene
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene’s expression. These findings, published in the journal Stem Cells, imply that this region within GLI1 could potentially be targeted as cancer treatment, since turning off GLI1 would interrupt excessive cell division characteristic of cancer.
Brain Cancer: UVA IDs Gene Responsible for Deadly Glioblastoma
The discovery of the oncogene responsible for glioblastoma could be the brain tumor’s Achilles’ heel, one researcher says.
St. Jude researchers create an analytic tool that opens a new frontier of cancer discovery
St. Jude Children’s Research Hospital scientists have developed software to identify cancer-causing mutations lurking in vast regions of the human genome