For human testing of antiviral drug EIDD-2801
Tag: VIROLOGY
Family of crop viruses revealed at high resolution for the first time
For the first-time we can take a molecular-level look at one of the world’s deadliest crop killers. The Luteoviridae are pathogenic plant viruses responsible for major crop losses worldwide. Transmitted by aphids, the viruses infect a wide range of food…
CRISPR enzyme programmed to kill viruses in human cells
Researchers harness Cas13 as an antiviral and diagnostic for RNA-based viruses
Rotavirus infection may turn on type 1 diabetes
Rotavirus infection may play a role in the development of type 1 diabetes, according to a front matter article published October 10 in the open-access journal PLOS Pathogens by Leonard C. Harrison of the University of Melbourne in Australia, and…
Morris Animal Foundation awards more than $1 million for small animal studies
DENVER/Oct. 8, 2019 – Morris Animal Foundation, a leader in advancing animal health, is awarding more than $1 million in grants for 16 canine and feline research projects. The studies will help veterinary scientists improve the health and quality of…
Bacteria trapped — and terminated — by graphene filter
Rice lab adapts laser-induced graphene to remove pathogens from the air
First video of viruses assembling
Research offers rare view into the formation of viruses
New bioinformatics hub at UChicago enables next-gen infectious disease research
NIH-funded resource merges pathogen databases and adds AI capabilities
How the influenza virus achieves efficient viral RNA replication
New insights on how subunits of the influenza virus polymerase co-evolve to ensure efficient viral RNA replication are provided by a study published October 3 in the open-access journal PLOS Pathogens by Nadia Naffakh of the Institut Pasteur, and colleagues.…
Cheap, quick test identifies pneumonia patients at risk of respiratory failure or sepsis
Madrid, Spain: Spanish researchers in Valencia have identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. Presenting the research at the European Respiratory Society International Congress [1] today…
Study demonstrates antibody responses within 6 weeks of initial vaccination
SEATTLE, OCTOBER 01, 2019 – An early phase study was conducted in the U.S. in which different combinations of DNA (DNA-HIV-PT123) and protein (AIDSVAX® B/E) vaccines were administered in four randomized treatment groups (T1, T2, T3, T4), to determine which…
Potent antibody curbs Nipah and Hendra virus attack
A monoclonal antibody prevents the virus from fusing with cell membranes to gain entry
Why viruses like Herpes and Zika will need to be reclassified, and its biotech impact
New findings reveal many different structural models, which can eventually lead to developing more targeted antiviral vaccines.
Geometry goes viral: Researchers use maths to solve virus puzzle
Researchers have developed a new mathematical framework that changes the way we understand the structure of viruses such as Zika and Herpes
Morris Animal Foundation awards more than $1 million for wildlife research grants
DENVER/September 27, 2019 – Morris Animal Foundation, a leader in advancing animal health, has awarded more than $1 million in wildlife health research grants, supporting 17 studies. The studies cover a diverse set of critical health challenges, including low fertility…
Viruses as modulators of interactions in marine ecosystems
GEOMAR scientists show a new picture of the role of viruses in the ocean
Morris Animal Foundation awards $940K for new studies benefiting horse/alpaca health
DENVER/September 26, 2019 – Morris Animal Foundation, a leader in advancing animal health, has awarded grants totaling $940,000 to 12 research projects in horse and alpaca health. The studies will help veterinary scientists improve the well-being of these large animals…
New fungus-derived antibiotic: relief in sight for immunocompromised people
Scientists derive a new compound from eushearilide, which can potentially take on lethal fungal and bacterial infections
A mouse or an elephant: what species fights infection more effectively?
Hamilton College researcher reveals body size shapes mammal immune defenses
West Nile virus in the New World: Reflections on 20 years in pursuit of an elusive foe
Array of experts on mosquito-borne disease weigh lessons learned and progress made in the Journal of Medical Entomology
Dengue virus becoming resistant to vaccines and therapeutics due to mutations in specific protein
Dengue virus (DENV) infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions. The virus causes diseases ranging from mild dengue fever to severe dengue haemorrhagic fever and dengue shock syndrome. DENV2…
A single dose of yellow fever vaccine does not offer lasting protection to all children
Yellow fever is a viral infection spread by various species of mosquito and is rife in 34 countries in Africa and 13 in Latin America. Infection may be asymptomatic and go unnoticed or, on the contrary, it may progress rapidly…
Towards better hand hygiene for flu prevention
Washington, DC – September 18, 2019 – Rubbing hands with ethanol-based sanitizers should provide a formidable defense against infection from flu viruses, which can thrive and spread in saliva and mucus. But findings published this week in mSphere challenge that…
Bat influenza viruses possess an unexpected genetic plasticity
An unprecedented genetic plasticity and a putative function of NA “Influenza viruses have an inherent high mutation rate,” explains Prof. Martin Schwemmle of the Medical Center – University of Freiburg and coordinator of this study. “We therefore first tested the…
Pew funds six research teams to pursue scientific discoveries
PHILADELPHIA–The Pew Charitable Trusts announced today the six pairs of researchers who will make up its 2019 class of Innovation Fund investigators. These investigators–alumni of Pew’s biomedical programs in the United States and Latin America–partner on interdisciplinary research to tackle…
Anemia may contribute to the spread of dengue fever
Iron-deficient blood makes it easier for dengue virus to colonize and multiply in mosquitoes’ guts
Simple model captures almost 100 years of measles dynamics in London
Disease dynamics are well predicted despite major disruptions caused by historical events
Chronic enteroviral infection modifies broadly pancreatic cellular functions
Enteroviral infections are common viral infections with usually rather few symptoms and also believed to be linked to the onset of type 1 diabetes. Type 1 diabetes is a disorder in which the pancreatic insulin-producing beta-cells are destroyed, and it…
Black sheep: Why some strains of the Epstein Barr virus cause cancer
The Epstein Barr virus (EBV) is very widespread. More than 90 percent of the world’s population is infected – with very different consequences. Although the infection does not usually affect people, in some it can cause glandular fever or various…
Zika virus infects the adult human brain and causes memory deficits in animal models
Brazilian researchers found the cause of neurological complications observed in adults patients infe
Helminthic infections may be beneficial against HIV-1
Infection with parasitic helminths can reduce the susceptibility of T-cells to HIV-1 infection, according to a study published September 5 in the open-access journal PLOS Pathogens by Esther de Jong of the University of Amsterdam and William Paxton of the…
New viruses discovered in endangered wild Pacific salmon populations
Three new viruses — including one from a group of viruses never before shown to infect fish — have
Livestock disease risk tied to herd management style
A new study provides an updated picture of the prevalence of the sheep and goat plague virus (PPRV), a widespread and often fatal disease that threatens 80 percent of the world’s sheep and goats, in northern Tanzania. According to the…
Texas Biomed hires new primate center researcher
Professor studies the impact of cannabinoids on HIV infection and inflammation
People’s initial immune response to dengue fever analyzed
Researchers have come one step closer to understanding how our immune system responds to acute dengue fever, a disease that has affected hundreds of thousands of people in Southeast Asia this summer alone. In a study published today in Nature…
Some vaccine doubters may be swayed by proximity to disease outbreak, study finds
An individual’s trust in institutions such as the CDC, and how close they live to a recent measles outbreak, may affect their attitudes on measles vaccination, according to a study published August 28, 2019 in the open-access journal PLOS ONE…
Smartphone-based device for detecting norovirus, the ‘cruise ship’ microbe
SAN DIEGO, Aug. 27, 2019 — Made infamous by outbreaks on cruise ships, norovirus can really ruin a vacation, causing severe vomiting, diarrhea and stomach pain. But the highly infectious virus can also strike closer to home, with water- and…
To stop mosquito-transmitted illnesses, pay attention to how humans behave: study
Targeting the mosquito population within a defined area is the primary way scientists and public health officials mitigate the spread of diseases caused by viruses like Zika, dengue fever, and West Nile. But researchers have discovered that evaluating how humans…
Technique combats widespread passion fruit disease
Experiments performed in Brazil show that systematic eradication of plants contaminated by cowpea ap
Expression of M gene segment of influenza A virus determines host range
The host range of the influenza A virus (IAV) is restricted by dysregulated expression of the M viral gene segment, according to a study published August 15 in the open-access journal PLOS Pathogens by Anice Lowen and John Steel of…
Birth defects associated with Zika virus infection may depend on mother’s immune response
New research led by scientists at The Rockefeller University in New York may help explain why Zika virus infection causes birth defects in some children but not others. The study, which will be published August 14 in the Journal of…