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UrduCima Universidad de Navarra (Spain) scientists have developed this novel method which detects asymptomatic cases with more than 95% sensitivity. They make the protocol available to the scientific community.
Tag: PHARMACEUTICAL/COMBINATORIAL CHEMISTRY
Hidden symmetry found in chemical kinetic equations
Rice University discovery has implications for drug design, genetics, more
New STM technique points way to new and purer pharmaceuticals
Using an ultra-thin and sharp needle tipped with a single carbon monoxide molecule frozen to minus 266 degrees centigrade, researchers from the University of Warwick and Cardiff identified and mapped the location of every molecular bond on the surface of…
New STM technique points way to new and purer pharmaceuticals
Using an ultra-thin and sharp needle tipped with a single carbon monoxide molecule frozen to minus 266 degrees centigrade, researchers from the University of Warwick and Cardiff identified and mapped the location of every molecular bond on the surface of…
High cost of cancer drugs not always justified
A growing number of new cancer drugs have come on the market in recent years, yet the cost of therapies in Europe and the United States have risen. This is driving up healthcare costs, which poses a challenge not only…
High cost of cancer drugs not always justified
A growing number of new cancer drugs have come on the market in recent years, yet the cost of therapies in Europe and the United States have risen. This is driving up healthcare costs, which poses a challenge not only…
COVID-19: A wake-up call to rebalance the drug supply chain?
Over 80% of chemicals used to make pharmaceuticals sold in Europe originate from China or India, according to the European Fine Chemicals Group. When COVID-19 emerged in Wuhan and spread across the globe, experts worried about disruption of the drug…
Venatorx Pharmaceuticals and GARDP partner to develop new antibiotic
Collaboration to accelerate development of cefepime-taniborbactam as a treatment for hospital acquired infections, including those caused by carbapenem-resistant Enterobacteriaceae and Pseudomonas aeruginosa
COVID-19: A wake-up call to rebalance the drug supply chain?
Over 80% of chemicals used to make pharmaceuticals sold in Europe originate from China or India, according to the European Fine Chemicals Group. When COVID-19 emerged in Wuhan and spread across the globe, experts worried about disruption of the drug…
Venatorx Pharmaceuticals and GARDP partner to develop new antibiotic
Collaboration to accelerate development of cefepime-taniborbactam as a treatment for hospital acquired infections, including those caused by carbapenem-resistant Enterobacteriaceae and Pseudomonas aeruginosa
Less addictive form of buprenorphine may help curb cocaine relapse
Mouse study shows buprenorphine analog is more effective with reduced potential for abuse
Chris Vanderwal to receive Springer Heterocyclic Chemistry Award 2020
Prize for outstanding research in heterocyclic chemistry goes to young professor from the University of California, Irvine
Designing peptide inhibitors for possible COVID-19 treatments
Scientists across the globe are rushing to find inhibitors of SARS-CoV-2, the new coronavirus behind the COVID-19 pandemic. Some are using computer simulations to identify promising compounds before conducting actual experiments in the lab. Now, researchers reporting in ACS Nano…
Alzheimer’s patients may need dosing changes in medicines prescribed for other conditions
Patients with Alzheimer’s disease (AD) are often prescribed drugs for other conditions — including diabetes or high blood pressure — at the same doses as those without dementia. That practice might need to be reexamined in the wake of new…
Making chemistry education more engaging with computers
The recent COVID-19 outbreak has been the main reason behind several temporary school closures around the world. This has made the idea of continuing to pursue educational activities during this time a challenging proposition. The current lockdowns implemented in different…
Alzheimer’s patients may need dosing changes in medicines prescribed for other conditions
Patients with Alzheimer’s disease (AD) are often prescribed drugs for other conditions — including diabetes or high blood pressure — at the same doses as those without dementia. That practice might need to be reexamined in the wake of new…
Making chemistry education more engaging with computers
The recent COVID-19 outbreak has been the main reason behind several temporary school closures around the world. This has made the idea of continuing to pursue educational activities during this time a challenging proposition. The current lockdowns implemented in different…
New method created by Skoltech scientists will make doping tests quicker
Skoltech scientists and their colleagues proposed a way to simplify the search for traces of medicines, narcotic substances and sports doping drugs in human biological samples by performing two additional tests with the search domain reduced tenfold. Scientists determine the…
To make or to break: Novel reversible technique produces acyl fluoride using rare metal
Scientists devise a new technique to produce value-added complex acyl fluorides from commercially available simple acyl fluoride
Bentham Book Series, Frontiers in Natural Product Chemistry, indexed in Scopus
Frontiers in Natural Product Chemistry [ISSN / E-ISSN: 1574-0897 / 2212-3997], has been accepted for inclusion in Scopus. Scopus is the largest abstract and citation database of peer-reviewed literature including scientific journals, books and conference proceedings. Frontiers in Natural Product…
Putting remdesivir to the test for COVID-19
As the coronavirus pandemic claims lives and overwhelms health care systems throughout the world, scientists are closely watching several late-stage trials of the antiviral drug remdesivir. Developed to treat Ebola, remdesivir is now being tested against COVID-19. However, many infectious…
Rice chemist wins grant to simplify drug design
Fed award to László Kürti will support sophisticated, simplified drug precursors
Synthesis against the clock
Novel radiopharmaceutical for the diagnosis of tumor-relevant transport proteins developed
CAS releases open access dataset of antiviral chemical compounds to aid COVID-19 analysis
Columbus, OH, April 2, 2020 – CAS, a division of the American Chemical Society specializing in scientific information solutions, is partnering with research and technology organizations worldwide to tackle the complex challenges presented by COVID-19. In support of calls to…
Innovation for humanity
Chemical engineering professor Michelle O’Malley recognized for work in biological, medical fields
Fatty acid in triglycerides proves an effective platform for biological drug delivery
HOUSTON-(April 1, 2020)-We’ve all been warned about the dangers of triglycerides, the fat stored in your blood. But what if that unhealthy fat could effectively transport oral medication to your body and eliminate the need for some injections or IV…
Clopidogrel atop rivaroxaban and aspirin shows no added benefit for PAD
Subgroup analysis suggests concomitant use of clopidogrel may not play role after PAD revascularizations
Evinacumab cuts cholesterol levels by half in patients with HoFH
Monoclonal antibody effective for the full spectrum of homozygous familial hypercholesterolemia
Oral apixaban as good as dalteparin for treating cancer-associated clots
No increase in the risk of major bleeding seen, including for gastrointestinal cancers
Renal denervation effective in patients with untreated hypertension
No serious adverse effects seen after three months of follow-up
Ticagrelor alone, without aspirin, shows benefit in patients with diabetes
No increase in bleeding, heart attack or stroke in TWILIGHT trial subanalysis
Phage capsid against influenza: Perfectly fitting inhibitor prevents viral infection
A new approach brings the hope of new therapeutic options for suppressing seasonal influenza and avian flu: On the basis of an empty – and therefore non-infectious – shell of a phage virus, researchers from Berlin have developed a chemically…
Pharma’s potential impact on water quality
When people take medications, these drugs and their metabolites can be excreted and make their way to wastewater treatment plants. From there, the compounds can end up in waterways. Wastewater from pharmaceutical companies could start off with even larger amounts…
For clogged and hardened hearts, a mussel is the solution
Early mortality of myocardial infarction (MI), one of fatal diseases, is about 30%. So, it is critical to have immediate and proactive treatment to prevent a heart attack. Contributing to developing an efficient treatment of this fatal disease, a research…
Scientists proposed a way of producing water-soluble fullerene compounds for medicine
Scientists from the Skoltech Center for Energy Science and Technology (CEST) and the Institute for Problems of Chemical Physics of Russian Academy of Sciences in collaboration with researchers from the Catholic University of Leuven (Belgium) developed a single-step method to…
Special report highlights potential therapeutic agents, vaccines for COVID-19
Since the first reports of a new coronavirus disease in Wuhan, China, in December 2019, COVID-19 has spread rapidly across the globe, threatening a pandemic. Now, researchers from CAS, a division of the American Chemical Society specializing in scientific information…
Heat and light create new biocompatible microparticles
Innovative manufacturing technique can create new types of microparticles for applications such as drug delivery, diagnostics and tissue engineering
A hidden electronic transition ‘S0 → Tn’ in heavy-atom-containing molecules
Researchers in Japan have discovered S0 → Tn, a previously overlooked electronic transition in photoreactions occurring in heavy-atom-containing molecules exposed to visible light. The study was published online in Angewadte Chemie International Edition on March 9, 2020. In recent years,…
Magnolia bark compound could someday help treat drug-resistant epilepsy
In patients with epilepsy, normal neurological activity becomes disrupted, causing debilitating seizures. Now, researchers report in ACS Chemical Neuroscience that they have found a potential new treatment for this disorder by turning to traditional Chinese medicine. Tests of extracts from…
MacMillan illuminates the micro-environment, creating a new path to cancer drugs
Princeton University’s Dave MacMillan led the effort to create a nanoscale map of proteins and their nearest neighbors.
Tissue-digging nanodrills do just enough damage
Scientists advance case for use of molecular machines to treat skin diseases
MacMillan illuminates the micro-environment, creating a new path to cancer drugs
Princeton University’s Dave MacMillan led the effort to create a nanoscale map of proteins and their nearest neighbors.
Tissue-digging nanodrills do just enough damage
Scientists advance case for use of molecular machines to treat skin diseases
Collapsible basket technology aims to improve drug discovery, personalized medicine
WEST LAFAYETTE, Ind. – A drug discovery scientist typically screens up to 10,000 compounds in the early stages of developing one FDA approved drug. During this high-throughput screening, candidate compounds are initially tested on cell and tissue samples. Such experiments…
SMART announces revolutionary new process for scientific applications
New microfluidic process enables researchers to create unique environment for developing medicine that cannot be achieved through conventional methods, paving the way for more potent, high-quality drugs
UArizona study identifies hormone that causes women to experience more pain than men
TUCSON, Ariz. – Imagine taking a pill to control your pain and, instead, the medication actually increases the pain you feel. That may be the situation for patients who take opioids, but even more so for women, according to groundbreaking…
Collapsible basket technology aims to improve drug discovery, personalized medicine
WEST LAFAYETTE, Ind. – A drug discovery scientist typically screens up to 10,000 compounds in the early stages of developing one FDA approved drug. During this high-throughput screening, candidate compounds are initially tested on cell and tissue samples. Such experiments…
SMART announces revolutionary new process for scientific applications
New microfluidic process enables researchers to create unique environment for developing medicine that cannot be achieved through conventional methods, paving the way for more potent, high-quality drugs
UArizona study identifies hormone that causes women to experience more pain than men
TUCSON, Ariz. – Imagine taking a pill to control your pain and, instead, the medication actually increases the pain you feel. That may be the situation for patients who take opioids, but even more so for women, according to groundbreaking…
On the path toward non-addictive painkillers
Acidity at source of pain is deciding factor