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UrduSparked by several high-profile reports, electrochemistry — using electricity to perform chemical reactions like oxidation and reduction — is gaining popularity in the pharmaceutical field. Some researchers have embraced the technology as a tool to synthesize compounds that are difficult…
Tag: PHARMACEUTICAL CHEMISTRY
New technology promises improved treatment of inflammatory diseases
Nanoparticles can selectively kill ‘rogue’ white blood cells that contribute to sepsis, stroke
New technology promises improved treatment of inflammatory diseases
Nanoparticles can selectively kill ‘rogue’ white blood cells that contribute to sepsis, stroke
Blood cancers: New generation stem cell transplant significantly reduces complications for patients
The discovery of the UM171 molecule, by Dr. Guy Sauvageau and Anne Marinier, made headlines in 2014 following an article in Science. Hailed by some as a revolution, even a miracle, in the field of blood stem cell transplantation, the…
Turning wood into pharmaceutical ingredients
Production of hazardous waste during drug manufacturing is a serious concern for the pharmaceutical industry. Typically, large amounts of flammable solvents are used during these processes, which usually require several steps to make structurally complex drugs. Researchers now report in…
AAIH releases primer to advance understanding within the industry
Technical whitepaper, as well as a high-level overview, seek to define a foundational lexicon and illustrate real-world applications of this growing technological movement to improve patient outcomes
From ribbon to scroll: Gaining shape control by electrostatics
Controlling scroll-like cochleate structures could inform future drug-delivery strategies
Drug discovery platform may provide new options for treating mental health illnesses
WEST LAFAYETTE, Ind. – An estimated 46.6 million U.S. adults struggle with mental illnesses, such as anxiety disorder, according to the National Institute of Mental Health. About half of millennials and 75% of Gen-Zers report having quit jobs for mental…
SLAS Discovery releases special issue
‘Membrane proteins: New approaches to probes, technologies and drug design’ now available
A Lego-like approach to improve nature’s own ability to kill dangerous bacteria
Research capitalizes on ability of enzymes to target and kill bacteria, improving possible solution to problem of antibiotic resistance
Pioneering red light-activated anti-tumor prodrug reduces side effects
Most of the current clinical anti-tumor drugs used in chemotherapy move around in the patient’s blood after intake and are unable to pinpoint the targeted tumor. As a result, while killing the tumor cells, the healthy cells may also be…
Did IV high-dose vitamin C improve outcomes for patients with sepsis and severe lung condition?
Bottom Line: This randomized clinical trial looked at whether high-dose vitamin C delivered intravenously could reduce organ failure, inflammation and vascular injury in patients with sepsis and acute respiratory distress syndrome (ARDS), a severe lung condition that is a common…
New species of parasite is identified in fatal case of visceral leishmaniasis
Phylogenomic analysis shows that pathogen isolated in Brazilian hospital does not belong to the genus Leishmania; researchers are investigating whether this species alone can cause severe disease or intensifies symptoms in co-infected patients
IU School of Medicine awarded $36 million NIH grant for Alzheimer’s drug discovery center
INDIANAPOLIS — Indiana University School of Medicine has been awarded a grant expected to total $36 million over five years from the National Institutes of Health to launch a drug discovery center to accelerate the development of promising treatments for…
CNPIEC has awarded ‘Partner of Excellence’ status to Bentham Science
China National Publications Import & Export (Group) Corporation (CNPIEC) awarded “Partner of Excellence” status to Bentham Science Publishers on its 70th birthday. China National Publications Import & Export (Group) Corporation (CNPIEC) is a large state owned culture enterprise founded in…
US government backs Sydney spinout company Kinoxis Therapeutics to fight opioid addiction
Funding to support development of a potential treatment for opioid withdrawal
Genetic markers linked to the start of symptoms of Parkinson’s disease
New therapeutic targets
Extra amino acid could work wonders
Rice University chemist uses designer amino acids in search for new cures
Temple scientists solve mystery underlying heart toxicity caused by diabetes drugs
(Philadelphia, PA) – Like catching two fish with one worm, treating two problems with a single drug is efficient, but exceedingly difficult. In particular, for new diabetes medications, in which one drug aims to tackle two major complications of diabetes…
AI-guided robotics enable automation of complex synthetic biological molecules
Overcomes bottlenecks of time-consuming, labor-intensive manufacturing processes
Turbo-charging pharmaceutical biotechnology simulations
Demand for biopharmaceuticals is strong: biopharmaceutical active ingredients – in other words, genetically engineered drugs – accounted for seven of the ten top-selling medications in the world in 2018. And the proportion is set to rise, as biopharmaceuticals can be…
TTUHSC researchers to investigate effects of vaping on the brain
For the past decade, the popularity of electronic cigarette use, or vaping, has grown significantly, especially among adolescents and former smokers who view these electronic nicotine delivery systems, or e-cigarettes, as a safe alternative to traditional tobacco smoking. Though the…
Scientists discover hidden differences among cells that may help them evade drug therapy
The discovery by UMD researchers suggests ‘functional mosaicism’ could explain some antibiotic resis
UTA scientist explores using nanoparticles to reduce size of deep-seated tumors
Another collaborative project from a nanoparticles expert at The University of Texas at Arlington has yielded promising results in the search for more effective, targeted cancer treatments. Wei Chen, in collaboration with colleagues from the University of Rhode Island and…
Evolution designed by parasites
While analyzing interactions between parasites and hosts, a substantial amount of research has been devoted to studying the methods parasitic organisms use to control host behavior. In “Invisible Designers: Brain Evolution Through the Lens of Parasite Manipulation,” published in the…
WPI biologist’s discovery gives evolution clues and may affect drug interaction research
Worcester, Mass. – August 15, 2019 – A biologist at Worcester Polytechnic Institute (WPI) has shown that a key biological component in a worm’s communication system can be repurposed to take on a different job, a critical finding about the…
Solving the big problem of measuring tiny nanoparticles
Tiny nanoparticles play a gargantuan role in modern life, even if most consumers are unaware of their presence. They provide essential ingredients in sunscreen lotions, prevent athlete’s foot fungus in socks, and fight microbes on bandages. They enhance the colors…