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UrduMargaret M. McCarthy, PhD, an internationally-recognized neuroscientist, who is the James and Carolyn Frenkil Dean’s Endowed Professor in the University of Maryland School of Medicine’s Department of Pharmacology, Physiology, and Drug Development, and Director of the University of Maryland – Medicine Institute of Neuroscience Discovery (UM-MIND), has been elected as a new member of the National Academy of Medicine.
Tag: Neuropsychiatric Disorders
Anne Bang joins $12.7M research project on the genetic basis of autism and schizophrenia
Scientists have linked neuropsychiatric disorders, such as schizophrenia and autism, to changes in many genes involved in early brain development. However, more research is needed to understand how these gene variants influence the biological mechanisms that underlie these disorders.
Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts
Using new sequencing technologies, UCLA and University of Pennsylvania researchers uncovered 214,516 unique isoforms in the developing neocortex — over 70% of which have not been previously studied.
MIRA Pharmaceuticals in Discussions with Memorial Sloan Kettering to Collaborate on Preclinical Cancer Pain Model Utilizing The Company’s Novel Oral Ketamine Analog
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA) (“MIRA” or the “Company”), a pre-clinical-stage pharmaceutical company focused on the treatment of neurologic and neuropsychiatric disorders, announced it is in advanced discussions with Memorial Sloan Kettering Cancer Center (MSK) to initiate a preclinical study evaluating MIRA’s novel oral ketamine analog, Ketamir-2, for the treatment of cancer-related pain and depression.
Researchers Wrestle with Accuracy of AI Technology Used to Create New Drug Candidates
Researchers at the UNC School of Medicine, UCSF, Stanford, and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.
A New Study Shows How Neurochemicals Affect fMRI Readings
A landmark study, led by Yen-Yu Ian Shih, PhD, at the UNC School of Medicine, shows how neurochemicals can influence blood vessels. The new findings may alter how researchers interpret results from functional magnetic resonance imaging.
Rare Human Gene Variant in ADHD, Autism Exposes Fundamental Sex Differences
Key differences in male and female mice brains provide new insights into how sex determines the mechanisms by which distinct synapses monitor and regulate dopamine signaling. The impact of sex differences is particularly pronounced when the mice express a human genetic variant found in boys with either ADHD or autism. Behavioral generalizations across the sexes may limit diagnosis of mental illness, especially if one sex translates alterations into outward signs such as hyperactivity and aggression vs. more internal manifestations such as learning, memory and mood, even when the same molecular pathology is at work.
ADHD and impulsivity: New potential targets to approach the treatment for neuropsychiatric disorders
A study published in the journal Pharmacological Research describes the existence of a complex built by dopamine and noradrenergic receptors that could be a therapeutic target of potential interest to tackle the attention deficit hyperactivity disorder (ADHD) and impulsivity.
Who’s in cognitive control?
A new study into cognitive control from the lab of Todd Braver promises to be the first of many aimed at understanding its origins in the brain and its variations between people and among groups.
Wayne State University researcher invited to edit book on neuropsychiatry
A Wayne State University School of Medicine faculty member is editor of a newly published book, Brain Network Dysfunction in Neuropsychiatric Illness: Methods, Applications & Implications, published by Springer Nature Publishing.