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UrduA 25% reduced gadobutrol dose demonstrated non-inferior efficacy versus 100%-standard dose of gadoterate for contrast-enhanced brain MRI, particularly in patients undergoing multiple contrast-enhanced examinations
Tag: Neurobiology
Close-up look at brain uptake of omega-3
SINGAPORE, 17 June 2021 – New details on the structure and function of a transport protein could help researchers develop drugs for neurological diseases that are better able to cross the blood-brain barrier. The findings were published in the journal…
FDA advisory panelist outlines issues with aducanumab’s approval for Alzheimer’s disease
Below please find a summary for a new article that will be published today in Annals of Internal Medicine . The summary is not intended to substitute for the full article as a source of information. This information is under…
Omega-3s may hold key to unlocking blood-brain barrier
NEW YORK, NY (June 16, 2021)–Spectacular images of a molecule that shuttles omega-3 fatty acids into the brain may open a doorway for delivering neurological therapeutics to the brain. “We’ve managed to obtain a three-dimensional structure of the transporter protein…
How do we know where things are?
Study looks at how the visual system stabilizes what you see when you move your eyes
Immune system dysfunction can modify the association between cannabis use and psychosis
Brazilian researchers show that a combination of inflammatory cytokines in the blood and cannabis use, daily or during adolescence, heightens the odds of developing psychiatric disorders
P-glycoprotein removes Alzheimer’s-associated toxin from the brain
Discovery could lead to new Alzheimer’s treatment
SNMMI Image of the Year: PET imaging measures cognitive impairment in COVID-19 patients
Reston, VA–The effects of COVID-19 on the brain can be accurately measured with positron emission tomography (PET), according to research presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2021 Annual Meeting. In the study, newly diagnosed COVID-19…
A distinctive inflammatory signature found in a genetic form of ALS
Researchers find an increase in inflammatory molecules in serum and cerebrospinal fluid of C90RF72 patients, informing future anti-inflammatory therapies
Summer Thyme is named a Pew Scholar in the biomedical sciences
Only 22 early-career researchers were selected as Pew Scholars this year, and Thyme is one of five whose research focus is the brain
Graphene ‘camera’ captures real-time electrical activity of beating heart
Graphene sheet acts like video camera to record fleeting electrical signals of neurons, cardiac cells
Researchers translate a bird’s brain activity into song
Study demonstrates the possibilities of a future speech prosthesis for humans
Researchers find human infant brains, bodies are active during new sleep stage
Human babies do even more than we thought while sleeping. A new study from University of Iowa researchers provides further insights into the coordination that takes place between infants’ brains and bodies as they sleep. The Iowa researchers have for…
Novel calibration procedure for super-resolution brain imaging
A simple and robust procedure corrects a systematic error in microscopy, enabling precise imaging of biological tissue at greater depth
AASM congratulates 2021 Trainee Investigator Award recipients
Award recognizes outstanding research presented at the SLEEP annual meeting
Research papers that omit ‘mice’ from titles receive misleading media coverage
Study suggests relationship between how scientists communicate findings and how journalists report research to public
New treatment stops progression of Alzheimer’s disease in monkey brains
A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows. Led by researchers at NYU…
Main gland in hormonal system ages due to process that can potentially be slowed down
Stem cell biologist Hugo Vankelecom (KU Leuven) and his colleagues have discovered that the pituitary gland in mice ages as the result of an age-related form of chronic inflammation. It may be possible to slow down this process or even…
Fitbit user data show slight increase in sleep duration in US during COVID-19 pandemic
Data from more than 163,000 Fitbit users allow large-scale analysis of sleep variables
Telemedicine program improves access to sleep care for rural veterans
Number of veterans seen at VHA TeleSleep locations tripled between 2017 and 2020
A new model of Alzheimer’s progression
Alzheimer’s disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease and cause eventual…
A ‘pump’ gene’s surprising role in early brain formation
A mutation in four children with polymicrogyria illuminates the role of bioelectricity in early brain development
USC study reveals potential new treatment target for Alzheimer’s disease
Researchers at Keck School of Medicine of USC identify a novel target related to the blood-brain barrier and a potential therapy that offers hope for slowing progression of Alzheimer’s disease in people with the APOE4 gene
Breeding foxes for opposite behaviors produces similar brain changes
Tame and aggressive foxes display increased size in similar brain regions, contrary to theory
Two decade analysis of African neuroscience research prompts calls for greater support
With the world’s largest human genetic diversity, experts believe Africa is vital to help progress neuroscience research
New super-resolution technique allows for more detailed brain imaging
Reston, VA (Embargoed until 5:00 p.m. EDT, Sunday, June 13, 2021) – A new imaging technique has the potential to detect neurological disorders–such as Alzheimer’s disease–at their earliest stages, enabling physicians to diagnose and treat patients more quickly. Termed super-resolution,…
Forget me not: Novel target shows promise in treating Alzheimer’s and related dementias
A novel tau protein conformation, cis P-tau, is a toxic early driver of Alzheimer’s disease and related dementias and silencing of this protein through immunotherapy ameliorates dementia symptoms in preclinical models
Winner Art of Neuroscience competition announced
The eleventh edition of the Art of Neuroscience competition is won by Yas Crawford, an associate of the Royal Photographic Society and independent artist. With her artwork ‘Cognition IX’, Crawford looks at neurological interoception in Myalgic Encephalomyelitis (M.E) patients. The…
New study gives clue to the cause, and possible treatment of Parkinson’s Disease
Zebrafish model research reveals clues about molecular triggers of Parkinson’s Disease
Moral disgust has a ‘bad taste’
When we witness behaviours that violate shared moral norms, our brain inhibits the neurons that control our tongue movements – just like it happens when something tastes bad. An international research group led by the Universities of Bologna and Messina…
‘Roadmaps’ of the brain reveal regions vulnerable to Alzheimer’s disease
GRAND RAPIDS, Mich. (JUNE 10, 2021) — Much like a supply truck crossing the countryside, the misfolded proteins that damage neurons in Alzheimer’s disease travel the “roads” of the brain, sometimes stopping and sometimes re-routing to avoid roadblocks, reports a…
Like night and day: Animal studies may not translate to humans without time considerations
In a recent survey of published animal studies, researchers at West Virginia University found disregarding the animals’ circadian rhythms can hamper reproducibility, reliability and validity.
Largescale brain epigenetics study provides new insights into dementia
The largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linked to the disease.
Sleep societies announce inaugural Diversity, Equity and Inclusion Leadership Award
Award recognizes the work of Dr. Charlene Gamaldo of Johns Hopkins Medicine
Music listening near bedtime disruptive to sleep, Baylor study finds
Baylor sleep researcher Michael Scullin finds ‘earworms’ continue during sleep, can cause restless nights
CWRU researcher secures $1.2M to develop MS diagnostic tests
CLEVELAND–Case Western Reserve University researcher Farren Briggs was awarded $1.2 million over three years from the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health to identify biomarkers to improve the diagnoses of multiple sclerosis…
LSU Health New Orleans study reports compound blocks SARS-CoV-2 and protects lung cells
New Orleans, LA – Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that Elovanoids, bioactive chemical messengers made from omega-3 very-long-chain polyunsaturated fatty acids discovered by the Bazan lab in 2017, may block the virus that…
Depression in old age: Smoking and other risk factors less decisive
People who smoke, suffer from high blood pressure, obesity, or diabetes are not only at greater risk of suffering a stroke, heart attack, or dementia. For them, the risk of being affected by depressive mood or depression also increases. The…
Food for thought: Eating soft foods may alter the brain’s control of chewing
Incoming sensory information can affect the brain’s structure, which may in turn affect the body’s motor output. However, the specifics of this process are not always well understood.
Brain connections mean some people lack visual imagery
New research has revealed that people with the ability to visualise vividly have a stronger connection between their visual network and the regions of the brain linked to decision-making.
Elemental copper and iron found within the brains of deceased Alzheimer’s patients
Biogenic metallic elements in the human brain?
Artificial intelligence predicts brain age from EEG signals recorded during sleep studies
Brain age indices have potential value as diagnostic biomarkers and ‘vital signs’ of brain health
Game time and direction of travel are associated with college football team performance
Study suggests that circadian factors can influence performance of collegiate athletes
Having trouble falling asleep predicts cognitive impairment in later life
Study identifies an insomnia symptom that could be an intervention target for dementia prevention
Persistent insomnia symptoms since childhood associated with mood, anxiety disorders
Study emphasizes importance of early interventions to address insomnia symptoms in children
Wearable electroencephalogram device gathers reliable sleep data from the ear
Device has the potential to track changes in an individual’s neural signature over time
Study shows adaptive brain response to stress, and its absence in people with depression
A biological signal for resilience to stress
Preliminary genetic link to developmental coordination disorder, dyspraxia identified
New research by scientists at Oxford Brookes University has identified specific genes which could provide vital information about the biology of developmental coordination disorder (DCD), also known as dyspraxia. Dyspraxia is a common motor coordination condition which is estimated to…
Study of hyperhomocysteinemia in rats elucidates tracks to treating migraine
A paper saw light in Behavioural Brain Research.