La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body. Scientists from the La Trobe Institute of Molecular Science (LIMS), working…
Tag: IMMUNOLOGY/ALLERGIES/ASTHMA
Scientists crack rabies virus weaponry
Researchers from have found a way to stop the rabies virus shutting down the body’s immune defence against it.
$1.85 million NIH grant to study sepsis
One drop of blood contains 5,000 neutrophils, the most abundant type of white blood cell that is deployed by the human immune system. Throughout the entire body, a human has 25 billion of these foot soldiers that are relentlessly patrolling…
Boosting host immune defenses to treat tuberculosis
Current treatment regimens for Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, are long, complex, and hard for people to sustain. Moreover, the bacteria often develop drug resistance, and many people harbor multi-drug-resistant strains. In 2018 alone, nearly 1.5 million…
Scientists identify immune cells linked to malaria-induced anaemia through autoantibody production
Anaemia in malaria patients is likely caused by an autoimmune attack on uninfected red blood cells, suggesting a new approach to treating this deadly side effect
Cells control their dance of death
La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body. Scientists from the La Trobe Institute of Molecular Science (LIMS), working…
Boosting host immune defenses to treat tuberculosis
Current treatment regimens for Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, are long, complex, and hard for people to sustain. Moreover, the bacteria often develop drug resistance, and many people harbor multi-drug-resistant strains. In 2018 alone, nearly 1.5 million…
Fetal nicotine exposure harms breathing in infants
Neurons controlling the tongue could play a role in sudden infant death syndrome
Salmonella — how the body fights back
New research from the University of East Anglia shows how the human body powers its emergency response to salmonella infection. A study, published today in the journal PNAS , reveals how blood stem cells respond in the first few hours…
Fetal nicotine exposure harms breathing in infants
Neurons controlling the tongue could play a role in sudden infant death syndrome
Salmonella — how the body fights back
New research from the University of East Anglia shows how the human body powers its emergency response to salmonella infection. A study, published today in the journal PNAS , reveals how blood stem cells respond in the first few hours…
How prenatal diet, delivery mode and infant feeding relate to pediatric allergies
News briefs on two new studies
New technique to identify a common cause to TMA diseases for which there is a treatment
Researchers develop a new technique to identify a cause that is common to diseases related to thrombotic microangiopathies (TMA) for which there is a treatment that could be used more widely
Modified CRISPR gene editing tool could improve therapies for HIV, sickle cell disease
City of Hope’s cell experiments show more effective genetic ‘cuts’ that could one day become the foundation of new and more effective gene therapies
Groundbreaking HIV vaccine design strategy shows promise in proof-of-principle tests
A new approach that targets young immune cells may also work for creating vaccines against the flu, dengue, malaria and hepatitis C.
Dr. Yamamoto receives the Karl Landsteiner Memorial Award and Lectureship
Dr. Fumiichiro Yamamoto receives the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes
New technology promises improved treatment of inflammatory diseases
Nanoparticles can selectively kill ‘rogue’ white blood cells that contribute to sepsis, stroke
Dr. Yamamoto receives the Karl Landsteiner Memorial Award and Lectureship
Dr. Fumiichiro Yamamoto receives the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes
New technology promises improved treatment of inflammatory diseases
Nanoparticles can selectively kill ‘rogue’ white blood cells that contribute to sepsis, stroke
New mechanism for development of type 1 diabetes implicates more active role for ß cells
-Exposure of pancreatic islets cells to inflammatory cytokines results in the activation of non-coding DNA regions that act as “switches” to trigger gene expression and protein translation. This study has mapped these non-coding regions in islet cells. -Genetic variants that…
Discovered a new process of antitumor response of NK cells in myeloma
NK cells mean Natural Killer cells. They are part of the innate immune system. They are known primarily for their ability to recognize and kill tumor cells, cells infected by viruses and bacteria, or dying by apoptosis. Although evidence about…
NIH researchers estimate 17% of food-allergic children have sesame allergy
Scientists find sesame antibody testing predicts sesame allergy in food-allergic children
NIH researchers estimate 17% of food-allergic children have sesame allergy
Scientists find sesame antibody testing predicts sesame allergy in food-allergic children
NIH researchers estimate 17% of food-allergic children have sesame allergy
Scientists find sesame antibody testing predicts sesame allergy in food-allergic children
In unvaccinated children, ‘immune amnesia’ occurs in the wake of measles infection
Two separate investigations into the immune systems of 77 unvaccinated children before and after measles infection have revealed the infection can cripple immunity against viruses and bacteria for the long-term, creating a kind of “immune amnesia” that leaves individuals more…
Antihistamine use for anaphylaxis symptoms linked with delay seeking emergency treatment
Research shows a majority of families whose children were hospitalized for anaphylaxis turned first to antihistamines, which can’t prevent allergic reaction from becoming fatal
Anti-arthritis drug also stops tuberculosis bacillus from multiplying in blood stem cells
Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells. Tuberculosis (TB) may affect any…
New treatment may reverse celiac disease
New technology may be applicable to other autoimmune diseases and allergies
Immune reaction causes malaria organ damage
Immune cells can be the body’s defenders and foes at the same time
Stephan Grupp, MD, PhD, elected to National Academy of Medicine
Children’s Hospital of Philadelphia physician-scientist receives outstanding honor in medicine for work in cell and gene therapy
Cystic fibrosis carriers at increased risk of digestive symptoms
Findings reported at ASHG 2019 Annual Meeting
Syphilis infection rates in dialysis patients exceed general population
AUGUSTA, Ga. (Oct. 15 , 2019) – Syphilis rates, like other sexually transmitted disease rates in the United States, are soaring, and the first known study to examine syphilis rates in patients with kidney failure found an incidence greater than…
Newly identified compounds could help give fire ants their sting
Native to South America, imported fire ants have now spread to parts of North America and elsewhere around the world. These invasive pests have painful stings that, in some cases, can cause serious medical problems, such as hypersensitivity reactions, infections…
CRISPR enzyme programmed to kill viruses in human cells
Researchers harness Cas13 as an antiviral and diagnostic for RNA-based viruses
EMIDDT is now the official Journal of Italian Medical Endocrinology Association
Bentham Science Publishers is pleased to announce that the journal Endocrine, Metabolic & Immune Disorders – Drug Targets ( EMIDDT ) is now the official journal of Associazione Medici Endocrinologi (AME) / Italian Medical Endocrinology Association. The journal is currently…
Compound in breast milk fights harmful bacteria
Simple, inexpensive compound could be added to formula or cow’s milk
CUNY SPH awarded 2 grants to support public health programs on CUNY campuses
New York – The CUNY Graduate School of Public Health and Health Policy (CUNY SPH) Foundation has announced two new grants to launch and expand programs that focus on improving the health and wellbeing of CUNY students. The Levitt Foundation…
NCI-sponsored trial explores better treatment for brain tumors in children
AUGUSTA, Ga. (Oct. 8, 2019) Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these…
Cincinnati Children’s receives NIH grant renewal on eosinophilic disorders
CINCINNATI — Cincinnati Children’s Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health (NIH) to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic…
Secrets of lung cancer spread found in patients’ blood and biopsies
Early signs that a patient’s lung cancer may spread and become untreatable can be picked up in samples of their blood and tumour, according to a trio of papers published in Nature Medicine today (Monday). The three studies are all…
UNAIDS HIV targets will be missed among gay men in Africa, study suggests
Despite improvements in HIV testing among men who have sex with men (MSM) in Africa, many are missing out on HIV treatment. This is the finding of research, led by Imperial College London, which analysed data from 75 independent studies…
Atopic dermatitis: How allergens get on our nerves
Dry skin, pain, and itching… Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients. Several studies have…
New capsule can orally deliver drugs that usually have to be injected
Coated pill carries microneedles that deliver insulin and other drugs to the lining of the small intestine
Researchers discover a new defensive mechanism against bacterial wound infections
Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité – Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria. Central to this mechanism is a…
Scientists find timekeepers of gut’s immune system
Targeting such cells may lead to treatments for digestive ailments
CNIC scientists discover a new mechanism for the transfer of maternal genetic material
The study, published in Cell Metabolism, will help scientists devise ways to prevent the co-occurrence of different types of mitochondrial DNA in the same cell as an unwanted result of medical interventions
Engineered viruses could fight drug resistance
By engineering bacteriophage genomes, MIT team creates a new weapon to combat infection
Entos Pharmaceuticals announces research, development and collaboration agreement
EDMONTON, Alberta, October 2, 2019 — Entos Pharmaceuticals Inc. (“Entos” or the “Company”), a healthcare biotechnology company focused on the development of next-generation nucleic acid-based therapies using their Fusogenix drug delivery platform, today announced it has entered into a research,…
Father’s obesity in puberty doubles the risk of asthma in his future offspring
A Norwegian study shows that boys who are obese in pre-puberty have an over two times higher risk of having children with asthma than those who are not
Nerve-stimulating leg prosthesis improves movement and functionality in amputees
A research team has created a leg prosthesis for lower leg amputees that incorporates advanced neural stimulation, allowing it to recreate sensations of touch in the knee and foot that are missing in conventional prosthetic designs. The neuroprosthesis improved mobility…