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Tag: Cancer
Patients with advanced breast cancer are being denied access to life-prolonging drug
Experts also call for better access to opioid pain relief for patients
Genetic alterations caused by cancer therapies identified
Living implies change. This is what happens to the cells of our bodies as we grow older: they accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain genes and can lead…
Gut microbiota imbalance promotes the onset of colorectal cancer
The gastroenterology team at Henri-Mondor AP-HP Hospital and University Paris-Est Créteil, led by Professor Iradj Sobhani, together with teams from Inserm and the Institut Pasteur Molecular Microbial Pathogenesis Unit (U1202), led by Professor Philippe Sansonetti – holder of the Microbiology…
More children survive neuroblastoma
Both the survival rate and the incidence of neuroblastoma have increased in the last decennia, as was shown by a study from the Princess Máxima Center. The improved chance of survival and the increase in the number of patients has…
One-two punch drug combination offers hope for pancreatic cancer therapy
Study provides rationale for an immediate clinical trial evaluating the 2 therapies
From childhood cancer to mapping human development
Pioneering scientist awarded 2019 Foulkes Foundation medal
Omega-3 shows protection against heart disease-related death, without prostate cancer risk
Should you take omega-3 pills? Or try to have two to servings of omega-3 rich fish a week, as the American Heart Association recommends? It may seem a bit murky if you follow headlines about nutrition and health. That’s why…
New candidate cancer genes identified using math models
Results available to the research community via web-based portal
Children’s National Hospital, Virginia Tech announce partnership for new Children’s National Research & Innovation Campus
Children’s National Hospital and Virginia Tech announce a formal partnership that will include the construction of a 12,000-square foot Virginia Tech biomedical research facility within the new Children’s National Research & Innovation Campus.
Study: Multidisciplinary transplantation evaluation shows promise for older adults
Patients receiving integrative treatment plans prior to transplantation have improved outcomes
The ways astronauts prep for spaceflight could benefit cancer patients, say researchers
During spaceflight, astronauts experience similar physical stress as cancer patients undergoing treatments such as chemotherapy, immunotherapy, and targeted therapy. In a commentary published November 14 in the journal Cell , researchers suggest that by mimicking a NASA astronaut’s schedule of…
FDA accepts submission for selumetinib as treatment for neurofibromatosis
Would become first approved drug for genetic disorder affecting millions
FEFU scientists obtained new compounds with potential antitumor effect from sea sponge
Chemists from Far Eastern Federal University’s School of Natural Sciences (SNS FEFU) developed a new method to synthesize biologically active derivatives of fascaplysin — cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of…
Blocking a survival mechanism could tackle melanoma treatment resistance
The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the ‘survival system’ of cancer cells according to a study published in Nature Communications today.* Researchers from the…
How Crohn’s disease-associated bacteria tolerate antibiotics
Bacteria associated with Crohn’s disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14 in the open-access journal PLOS Pathogens by Olivier Espéli of the…
Researchers block metastasis-promoting enzyme, halt spread of breast cancer
Findings in mice point to new approach that may help make some metastatic breast cancers susceptible to immunotherapy
Study: Multidisciplinary transplantation evaluation shows promise for older adults
Patients receiving integrative treatment plans prior to transplantation have improved outcomes
The ways astronauts prep for spaceflight could benefit cancer patients, say researchers
During spaceflight, astronauts experience similar physical stress as cancer patients undergoing treatments such as chemotherapy, immunotherapy, and targeted therapy. In a commentary published November 14 in the journal Cell , researchers suggest that by mimicking a NASA astronaut’s schedule of…
FDA accepts submission for selumetinib as treatment for neurofibromatosis
Would become first approved drug for genetic disorder affecting millions
FEFU scientists obtained new compounds with potential antitumor effect from sea sponge
Chemists from Far Eastern Federal University’s School of Natural Sciences (SNS FEFU) developed a new method to synthesize biologically active derivatives of fascaplysin — cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of…
How Crohn’s disease-associated bacteria tolerate antibiotics
Bacteria associated with Crohn’s disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14 in the open-access journal PLOS Pathogens by Olivier Espéli of the…
Treatment with anti-cancer drug T-DM1 after pertuzumab is ‘good option’
Results from largest group of advanced breast cancer patients answers questions about efficacy of T-DM1 when cancer returns following treatment with pertuzumab
Blocking a survival mechanism could tackle melanoma treatment resistance
The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the ‘survival system’ of cancer cells according to a study published in Nature Communications today.* Researchers from the…
Researchers block metastasis-promoting enzyme, halt spread of breast cancer
Findings in mice point to new approach that may help make some metastatic breast cancers susceptible to immunotherapy
New Technique Aims to Improve Imaging of Cells
In research published in Proceedings of the National Academy of Sciences, a team from Rensselaer Polytechnic Institute developed and demonstrated a new technique for fluorescence lifetime imaging of tissue and cells in a fast and comprehensive manner — laying the groundwork for use in a clinical setting.
LUDWIG LAUSANNE’S PING-CHIH HO NAMED AN EMBO YOUNG INVESTIGATOR
Ludwig Cancer Research congratulates Ping-Chih Ho on his selection by the European Molecular Biology Association (EMBO) as a member of its Young Investigator Programme.
Twenty-seven life scientists become EMBO Young Investigators
Heidelberg, 13 November 2019 – EMBO congratulates twenty-seven life scientists on their selection as new EMBO Young Investigators. They join a network of 129 current and 340 former Young Investigators, and will begin their four-year programme tenure in January 2020.…
Analysis of melanoma in US by age groups
What The Study Did: This study used registry data to determine annual rates of melanoma in pediatric, adolescent, young adult and adult age groups, and the findings suggest an apparent decrease among adolescent and young adults between 2006 and 2015…
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers
The cover for issue 61 of Oncotarget features Figure 4, ‘The influence of stress conditions on API-5 expression and inhibition,’ by Bousquet, et al.
Pacemakers can improve heart function in patients with chemotherapy-induced heart disease
BOSTON – With the advent of new therapies, cancer patients are surviving longer than ever before — but the incidence of side-effect chemotherapy-induced cardiomyopathy (CHIC), or weakness of the heart muscle, is increasing. Research published in JAMA has shown that…
Leukaemia cells can transform into non-cancerous cells through epigenetic changes
All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects. For example, a lymphocyte and a neuron share the same genetic material, but they play very different tasks, and…
Precisely poking cells en masse to cure cancer
Device can mass-produce engineered cells at lower cost, a tipping point for emerging lifesaving therapies
Analysis of melanoma in US by age groups
What The Study Did: This study used registry data to determine annual rates of melanoma in pediatric, adolescent, young adult and adult age groups, and the findings suggest an apparent decrease among adolescent and young adults between 2006 and 2015…
Discovery: New biomarker for cancer stem cells
Protein linked to tumor survival and spread
Pacemakers can improve heart function in patients with chemotherapy-induced heart disease
BOSTON – With the advent of new therapies, cancer patients are surviving longer than ever before — but the incidence of side-effect chemotherapy-induced cardiomyopathy (CHIC), or weakness of the heart muscle, is increasing. Research published in JAMA has shown that…
Secondary surgery does not improve overall survival for recurrent ovarian cancer patients
Researchers from The University of Texas MD Anderson Cancer Center reported that secondary tumor-reduction, or cytoreduction, surgery followed by chemotherapy did not result in longer survival than chemotherapy alone in patients with platinum-sensitive recurrent ovarian cancer. The Phase III Gynecologic…
Driver found for more deadly prostate cancer
AUGUSTA, Ga. (Nov. 13, 2019) – A transcription factor that aids neuron function also appears to enable a cell conversion in the prostate gland that can make an already recurrent cancer even more deadly, scientists say. BRN4 is mostly expressed…
Study: Melanoma rates drop sharply among teens, young adults
Public health efforts to encourage sun-protection behaviors may be gaining traction, say UW Medicine and Fred Hutch researchers
Lung cancer survival is up, but more lives can be saved, new lung association report says
Second annual ‘State of Lung Cancer’ report explores what states can do to accelerate promising increase in survival rates
ELeCt-ing a better candidate for chemo delivery
Drug-loaded nanoparticles bound to circulating red blood cells inhibit lung cancer metastasis
Precisely poking cells en masse to cure cancer
Device can mass-produce engineered cells at lower cost, a tipping point for emerging lifesaving therapies
Yale study finds ‘hyperhotspots’ that could predict skin cancer risk
New Haven, Conn. — New research by Yale University scientists reports the discovery of “hyperhotspots” in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average. Exposure to…
Discovery: New biomarker for cancer stem cells
Protein linked to tumor survival and spread
Complementary therapies can do more harm than good when breast cancer becomes visible
Lisbon, Portugal: Patients with advanced breast cancer that has spread to the skin are likely to cause more harm than good if they use complementary therapies to treat their skin lesions. Professor Maria João Cardoso, head breast surgeon at the…
Twenty-seven life scientists become EMBO Young Investigators
Heidelberg, 13 November 2019 – EMBO congratulates twenty-seven life scientists on their selection as new EMBO Young Investigators. They join a network of 129 current and 340 former Young Investigators, and will begin their four-year programme tenure in January 2020.…
Giving breast cancer patients an average survival time is more often wrong than right
Lisbon, Portugal: Doctors who give advanced breast cancer patients just one estimate, such as 12 months, for the average amount of time they are expected to live are only accurate 20-30% of the time, according to Dr Belinda Kiely, medical…
Secondary surgery does not improve overall survival for recurrent ovarian cancer patients
Researchers from The University of Texas MD Anderson Cancer Center reported that secondary tumor-reduction, or cytoreduction, surgery followed by chemotherapy did not result in longer survival than chemotherapy alone in patients with platinum-sensitive recurrent ovarian cancer. The Phase III Gynecologic…
Lithium can reverse radiation damage after brain tumor treatment
Children who have received radiotherapy for a brain tumour can develop cognitive problems later in life. In their studies on mice, researchers at Karolinska Institutet have now shown that the drug lithium can help to reverse the damage caused long…
Study: Melanoma rates drop sharply among teens, young adults
Public health efforts to encourage sun-protection behaviors may be gaining traction, say UW Medicine and Fred Hutch researchers