WEST LAFAYETTE, Ind. — The human brain has some remarkable capabilities – including the ability to block cancer drugs from effectively reaching cancer cells in the brain. The greatest obstacle when it comes to treating cancer that has spread to…
Tag: Cancer
Using sound waves to remotely target drugs to tumors
Researchers have combined an ultrafast ultrasound imaging system with ultrasonic tweezers to track, trap and target drug carriers within a phantom blood vessel
Deep learning assists in detecting malignant lung cancers
OAK BROOK, Ill. – Radiologists assisted by deep-learning based software were better able to detect malignant lung cancers on chest X-rays, according to research published in the journal Radiology . “The average sensitivity of radiologists was improved by 5.2% when…
AI-driven single blood cell classification
New method to support physicians in leukemia diagnostics
Protein could offer therapeutic target for pancreatic cancer
A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified by researchers at the Crick. The study, published in Nature Cell Biology , looked into the most common type of…
Contraceptive drug shows promise for preventing and regressing cervical cancer
Findings reported in The American Journal of Pathology suggest medroxyprogesterone acetate as a new affordable non-invasive approach to combat cervical cancer, particularly for women with limited access to healthcare
Cardiac resynchronization therapy benefits cancer survivors with heart failure
A pacemaker-like device restored heart function in a group of cancer survivors — mostly women with breast cancer — who had suffered from heart failure as a result of chemotherapy treatment, a study in the Journal of the American Medical…
Study tests ‘medically tailored’ meals for patients with lung cancer to fight malnutrition
A new clinical trial at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) aims to reduce malnutrition among patients with lung cancer by offering nutritional counseling…
Cardiologists establish how e-cigarettes damage the brain, blood vessels and lungs
Cardiologists have issued a stark warning about the dangers of e-cigarettes, particularly for young people, as results of new research show the damage they cause to the brain, heart, blood vessels and lungs. The study, which is published in the…
Carbon dots make calcium easier to track
In hospitals, doctors often advise patients to take calcium supplements. But does the calcium get into the cells that need it? Until recently, it’s been hard to tell. But now, Prof. DONG Wenfei’s research group from the Suzhou Institute of…
Researchers find new way to target childhood cancer
Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells that therapeutic drugs can be at.
Anthrax may be the next tool in the fight against bladder cancer
WEST LAFAYETTE, Ind. – Anthrax may soon help more people win the fight against bladder cancer, which the Centers for Disease Control and Prevention says strikes about 72,000 Americans each year and kills about 16,000, and is one of the…
Young male cancer survivors may benefit from testosterone replacement
In young male cancer survivors with low testosterone levels, testosterone replacement therapy is associated with an improvement in body composition, according to a new study published this week in PLOS Medicine by Richard Ross of University of Sheffield, UK, and…
The gut may be the ticket to reducing chemo’s side effects
In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired.
New insights into cause and treatments for aggressive form of breast cancer
Potential environmental risk factors and new targets for treating an aggressive form of breast cancer have been identified, according to new data presented at the Society for Endocrinology annual conference in Brighton. The study suggests that exposure to common chemicals…
Ethnic minority women face more barriers to seeing their GP
The study published in Psycho-Oncology found that, in England, women from ethnic minority backgrounds were more likely to feel too embarrassed to talk to a GP (75-91%) than white women (8%). Being too scared that a symptom was a sign…
The Affordable Care Act’s impact on insurance coverage & treatment in patients with HIV and cancer
A recent study reveals that, for people living with both HIV and cancer (PLWHC), implementation of the Patient Protection and Affordable Care Act (ACA) improved insurance coverage, both in states that expanded Medicaid coverage and those that did not. Lack…
Team plucks needle from genomic haystack, finding essential transcription factor binding sites
Using CRISPR/Cas9 knockout screens a multi-institutional research team systematically interrogated the essentiality of more than 10,000 forkhead box protein A1 (FOXA1) and CTCF binding sites in breast and prostate cancer cells, plucking useful needles from a massive genomic haystack that…
Metaphor ‘menu’ for cancer patients launched by researchers
The first manual of expressions describing cancer has been developed by researchers to help patients make sense of their disease.
Lasting tumor regression of leukemia and lymphoma in mouse models achieved by U-M compound
A potent and selective degrader of the transcription factor STAT3 offers a new approach to a previously ‘undruggable’ target
The gut may be the ticket to reducing chemo’s side effects
Study in mice shows chemo affects gut, inflammation and cognitive problems
The Affordable Care Act’s impact on insurance coverage & treatment in patients with HIV and cancer
A recent study reveals that, for people living with both HIV and cancer (PLWHC), implementation of the Patient Protection and Affordable Care Act (ACA) improved insurance coverage, both in states that expanded Medicaid coverage and those that did not. Lack…
UC research finds potential target for tumor-causing condition
CINCINNATI — University of Cincinnati researchers have found additional ways to target the molecular processes involved in activating a certain protein complex to potentially develop new therapies for a tumor-causing disorder. These findings are being published in the Nov. 11…
NIH RO1 grant to help improve ultrasound tomography for breast cancer detection
Mammography is the current state-of-the-art method for detecting and diagnosing breast cancer. However, even a mammogram doesn’t detect certain subtle breast cancers, especially those in younger women who typically have denser breast tissue. In the growing need to improve imaging…
Team plucks needle from genomic haystack, finding essential transcription factor binding sites
Using CRISPR/Cas9 knockout screens a multi-institutional research team systematically interrogated the essentiality of more than 10,000 forkhead box protein A1 (FOXA1) and CTCF binding sites in breast and prostate cancer cells, plucking useful needles from a massive genomic haystack that…
Metaphor ‘menu’ for cancer patients launched by researchers
The first manual of expressions describing cancer has been developed by researchers to help patients make sense of their disease.
Lasting tumor regression of leukemia and lymphoma in mouse models achieved by U-M compound
A potent and selective degrader of the transcription factor STAT3 offers a new approach to a previously ‘undruggable’ target
The gut may be the ticket to reducing chemo’s side effects
Study in mice shows chemo affects gut, inflammation and cognitive problems
UC research finds potential target for tumor-causing condition
CINCINNATI — University of Cincinnati researchers have found additional ways to target the molecular processes involved in activating a certain protein complex to potentially develop new therapies for a tumor-causing disorder. These findings are being published in the Nov. 11…
NIH RO1 grant to help improve ultrasound tomography for breast cancer detection
Mammography is the current state-of-the-art method for detecting and diagnosing breast cancer. However, even a mammogram doesn’t detect certain subtle breast cancers, especially those in younger women who typically have denser breast tissue. In the growing need to improve imaging…
TTUHSC researchers publish preclinical data on new drug combination to treat neuroblastoma
Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most…
ESMO Asia Congress 2019 [ESMO media alert]
Asia 2019 Congress, Nov. 22-24, Singapore
Genetic diversity facilitates cancer therapy
Cancer patients with more different HLA genes respond better to treatment
Leading risk factors, causes of death underrepresented in NIH-supported prevention research
Study finds leading risk factors and causes of death and disability underrepresented in NIH-supported prevention research
VUMC’s Rathmell to Receive 2019 Eugene P. Schonfeld Award
The Kidney Cancer Association is recognizing the research accomplishments and leadership achievements of W. Kimryn Rathmell, MD, PhD, with its most prestigious honor, the Eugene P. Schonfeld Award.
Russian biotechnology company BIOCAD announced plans to enter the EU market
CPhI-2019 became the first large-scale international platform to present the BIOCAD’s latest original drugs based on monoclonal antibodies – netakimab and progolimab; plans were also announced for their entry to the European market
Learning to stop cancer at its roots
Why do some cancers come back? Sometimes, a treatment can effectively eliminate cancer cells to undetectable levels, but, if the treatment stops, cancer may return. This is the case of chronic myeloid leukemia treated with drugs known as tyrosine kinase…
New molecule reduces the aggressiveness of pediatric cancer
A microRNA inhibitor identified by researchers at the FAPESP-supported Human Genome and Stem Cell Research Center reduced the sizes of aggressive tumors and improved survival in mice
Cervical cancer screening numbers drop off in women 45-65
Although half of cervical cancers are detected in women over 49, a first-of-its-kind study finds women are less likely to get screenings as they age.
Researchers discover how cells know their future and forget their past
Stem cells all share the potential of developing into any specific cell in the body. Many researchers are therefore trying to answer the fundamental questions of what determines the cells’ developmental fate as well as when and why the cells…
Tailor-made for older adults, new tools improve doctor-patient relations
A Wilmot Cancer Institute-led study in JAMA Oncology shows that when physicians fully appreciate the concerns of older adults with cancer, such as function and forgetfulness, it elevates patient care and satisfaction. The study is believed to be the first…
NUS researchers discover enzyme’s role in ‘natural killer T cell lymphoma’
Natural killer T cell lymphoma (NKTL) is an aggressive form of cancer with very poor treatment outcomes in the advanced stages. NKTL generally affects the upper airways and digestive tracts in patients, but can also involve the gastrointestinal system, skin…
MD Anderson, Artios Pharma and ShangPharma announce in-licensing agreement for DNA damage response inhibitor
MD Anderson, Artios and ShangPharma have announced the in-licensing by Artios of a small-molecule ATR inhibitor program, developed jointly by MD Anderson and ShangPharma.
Brain cancer-detecting innovation by CCNY researchers receives two US patents
Raising hopes of rapid and more specific brain cancer diagnoses, a new “Resonance Raman” technique developed by world-renowned physicist Robert R. Alfano and his IUSL research group at The City College of New York is the recipient of two U.S.…
Scientists crack structure of a novel enzyme linked to cell growth and cancer
UC Riverside-led study could lead to the development of drugs that target liver and other cancers
Vitamin D dials down the aggression in melanoma cells
Vitamin D influences the behaviour of melanoma cells in the lab by making them less aggressive, Cancer Research UK scientists have found. The researchers from the University of Leeds discovered that vitamin D influences the behaviour of a signalling pathway…
Tumor-specific therapy targets ovarian cancer
UConn and UNC startup, Nami Therapeutics, develops nanotechnologies for targeted cancer therapy
A new machine learning approach detects esophageal cancer better than current methods
Researchers at Dartmouth’s Norris Cotton Cancer Center have created a deep learning model that can accurately identify cancerous esophagus tissue on microscopy images without the time-consuming manual data input required for current methods
Dr. Yamamoto receives the Karl Landsteiner Memorial Award and Lectureship
Dr. Fumiichiro Yamamoto receives the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes
How sweet it isn’t: Diminished taste function affects cancer patients’ food intake
UMass Amherst sensory expert seeks strategies to help patients eat well