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UrduGlenview, Ill. – Published monthly, the journal CHEST® features peer-reviewed, cutting-edge original research in chest medicine: Pulmonary, critical care, sleep medicine and related disciplines. Journal topics include asthma, chest infections, COPD, critical care, diffuse lung disease, education and clinical practice,…
Tag: PULMONARY/RESPIRATORY MEDICINE
Early antiviral response in the nose may determine the course of COVID-19
Cells sampled at the time of diagnosis from patients who later developed severe COVID-19 show a muted antiviral response, study finds
Advantages of intranasal vaccination against SARS-CoV-2
Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract
Study points to remotely supervised exercise classes as best option during lockdown
Based on data for 344 volunteers, Brazilian researchers compared the physical and mental health benefits of workouts led in person by a fitness instructor, unsupervised online sessions, and classes supervised remotely via video call
Prostate cancer treatment among black, white patients during pandemic
What The Study Did: This study included 647 patients with untreated nonmetastatic prostate cancer (269 patients during the pandemic and 378 from before the pandemic). During the initial COVID-19 lockdown, only 1% of Black men underwent prostatectomy, while 26% of…
Less-sensitive COVID-19 tests may still achieve optimal results if enough people tested
Analysis suggests same epidemiological outcomes possible with rapid-antigen versus RT-PCR tests
Researchers reverse emphysema in mice by injecting blood vessel wall cells
Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells–the cells that line the walls of blood vessels in the lung–can reverse the symptoms of emphysema. The study, which will be…
Association between COVID-19 exposure, self-reported compliance with public health guidelines among essential employees at an institution of higher education
What The Study Did: This study at an institution of higher education in Colorado evaluated the association between self-reported protective behaviors and how common SARS-CoV-2 infection was among essential in-person employees during the first six months of the COVID-19 pandemic…
A breath of fresh air for emphysema research
Tokyo, Japan – Chronic obstructive pulmonary disease (COPD) causes illness and death worldwide. It is characterized by destruction of the walls of tiny air sacs in the lungs, known as emphysema, and a decline in lung function. Little has been…
A small molecule induces readthrough of cystic fibrosis CFTR nonsense mutations
This research suggests that a path to treat currently untreatable cases of cystic fibrosis is clearly achievable.
Firefighters found to have persistent lung damage from Fort McMurray wildfire
Risk of developing asthma is more than doubled, says University of Alberta occupational health researcher who used the same parameters as a study on 9-11 first responders.
The journal CHEST receives Impact Factor of 9.410
Recently released in the latest Journal Citation Reports, the journal CHEST® , the official publication of the American College of Chest Physicians® (CHEST, received a Journal Impact Factor (JIF) of 9.410, up from 8.308 last year. The journal retained the…
COVID-19-related immigration concerns among Latinx immigrants in US
What The Study Did: T hese results suggest that substantial proportions of Latinx immigrants have immigration concerns about engaging in COVID-19-related testing, treatment and contact tracing. Authors: Carol L. Galletly, J.D., Ph.D., Medical College of Wisconsin in Milwaukee, i s…
Exploring gap between excess mortality, COVID-19 deaths in 67 countries
What The Study Did: N ational health care systems have different capacities to correctly identify people who died of COVID-19. Researchers in this study analyzed the gap between excess mortality and COVID-19 confirmed mortality in 67 countries to determine the…
Primary care payment model, telemedicine use for Medicare Advantage during pandemic
What The Study Did: The association between primary care payment models and the use of telemedicine for Medicare Advantage enrollees during the COVID-19 pandemic was examined in this study. Authors: Brian W. Powers, M.D., M.B.A., of Humana Inc. in Louisville,…
Inadequate sequencing of SARS-CoV-2 variants impedes global response to COVID-19
Better international sequencing efforts are needed to track and respond to new SARS-CoV-2 variants
The cells combating a deadly lung disease
A subset of fibroblasts located in small foci of tissue on the edges of extensive scarring produce a protein that protects against cell aging.
Launch of UNITE4TB partnership marks a new era in Tuberculosis treatment development
The partnership will accelerate the development of new Tuberculosis (TB) drug regimens as part of the Innovative Medicines Initiative (IMI), a public-private European Research & Development Consortium
Association of remdesivir treatment with survival, length of hospital stay among US veterans hospitalized with COVID-19
What The Study Did: I n this observational study using data from the Veterans Health Administration for 2,344 U.S. veterans hospitalized with COVID-19, remdesivir treatment was associated with prolonged hospitalization but wasn’t associated with improved survival. Authors: Michael E. Ohl,…
Sociodemographic characteristics, inequities associated with access to in-person, remote elementary schooling during pandemic in New York State
What The Study Did: Among the few New York state public school districts providing full-time in-person elementary school instruction during the COVID-19 pandemic, most districts served predominately white students, rural/suburban students and children who were not disadvantaged (children who were…
Like priming a pump, cells damaged by chronic lung disease can result in severe COVID
Results from a TGen-led international study suggest that SARS-CoV-2 takes advantage of genetic changes among patients with pre-existing lung diseases
CHEST releases expert guidelines for lung cancer screening
Glenview, Illinois – The American College of Chest Physicians® (CHEST) recently released a new clinical guideline, Screening for Lung Cancer: CHEST Guideline and Expert Panel Report . The guideline contains 16 evidence-based recommendations and an update of the evidence base…
New lung cancer screening course focuses on shared decision making
Glenview, IL – The American College of Chest Physicians® (CHEST) and Thomas Jefferson University are launching a free online educational program titled ” Shared Decision Making in Lung Cancer Screening ” to assist healthcare workers with identifying eligible patients for…
Association of socioeconomic characteristics with disparities in COVID-19 outcomes in Japan
What The Study Did: This study found an unequal pattern of COVID-19 outcomes that was associated with the socioeconomic circumstances in regions of Japan, suggesting that these disparities in COVID-19 outcomes aren’t unique to the United States and Europe. Authors:…
Changes in admissions to specialty addiction treatment facilities in California during COVID-19 pandemic
What The Study Did: T he COVID-19 pandemic was associated with a decline in addiction treatment initiations but more research is needed to understand the cause of the decline in initiations and the extent to which it was due to…
Effect of physician-delivered COVID-19 public health messages on adults’ knowledge, beliefs, practices related to COVID-19
What The Study Did: In this randomized clinical trial, a physician messaging campaign was effective in increasing COVID-19 knowledge, information-seeking and self-reported protective behaviors among diverse groups. Authors: Esther Duflo, Ph.D., of the Massachusetts Institute of Technology in Cambridge, is…
Symptoms of depression, anxiety among women experiencing homelessness/unstable housing during pandemic
What The Study Did: About half the women experiencing homelessness and unstable housing who were surveyed experienced symptoms of depression or anxiety or both during the pandemic and, in addition to unmet subsistence needs and social isolation, these symptoms were…
Short chain fatty acids: An ‘ace in the hole’ against SARS-CoV-2 infection
Scientists find that short chain fatty acids can be used to reduce susceptibility to SARS-CoV-2 infection and mortality from COVID-19
Scientists identify new gut-liver drug recycling process
Implications for developing treatments for intestinal diseases
Early anticoagulant treatment shown to reduce death in moderately ill COVID-19 patients
International RAPID Trial could contribute to clinical practice
Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality
Study suggests spatial relationship between COVID-19 mortality and population-level health factors
COVID-19 ARDS Focus of Latest ATS/CSL Behring Research Grant Recipient
New York, NY – July 13, 2021- The ATS Research Program is pleased to announce that William Zhang, MD, of Weill Cornell Medical Center is the recipient of the 2020-2021 ATS/CSL Behring Research Award in Acute Respiratory Distress Syndrome. The…
New research aims to improve treatments and outcomes for people with severe asthma
PrecISE study is now enrolling local patients and will use personalized medicine approach to test multiple therapies to treat severe asthma
Study assesses the prevalence of mental illness during the pandemic among folks aged 50-80
The study was conducted in the city of São Paulo, with over 2,000 participants who were active or retired staff of the University of São Paulo and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil).
Neither remdesivir nor HCQ affect viral clearance in hospitalized patients with COVID-19
Embargoed news from Annals of Internal Medicine
Reduced vs. standard CT dose for lung nodules in children, young adults with cancer
Reduced-dose CT depicts greater than 90% of lung nodules in children and young adults with cancer, identifying the presence of nodules with moderate sensitivity and high specificity
The incidence of COVID-19 in a Brazilian regional soccer league is one of the highest
Researchers analyzed almost 30,000 RT-PCR tests on swabs from 4,269 players in 2020: 11.7% turned out positive; the rate was the same as among front-line health workers
Changes in care delivery during COVID-19
What The Study Did: Researchers characterized clinical content of ambulatory care among office-based compared with telemedicine visits in the United States before and during the COVID-19 pandemic. Authors: G. Caleb Alexander, M.D., M.S., of the Johns Hopkins Bloomberg School of…
Disparities in vaccine acceptance among adults in China
What The Study Did: This survey study examined disparities in COVID-19 vaccine acceptance and approaches to improve vaccination rates among adults in China. Authors: Jingjing Ma, Ph.D., of Peking University in Beijing, is the corresponding author. To access the embargoed…
COVID-19 infections among health care workers before, after vaccination
JAMA Network Open
Children’s Hospital Colorado one of 7 US children’s hospitals driving asthma research
NIH awards $2.3 million to Colorado to support first long-term pediatric asthma study in emergency department patients experiencing asthma symptoms
Prolonged physiological, behavioral changes associated with COVID-19 infection
What The Study Did: W earable sensor data were used to examine the duration and variation of recovery among COVID-19-positive and COVID-19-negative participants. Authors: Jennifer M. Radin, Ph.D., M.P.H., of the Scripps Research Translational Institute in La Jolla, California, is…
Study shows laboratory developed protein spikes consistent with COVID-19 virus
A new international study has found that the key properties of the spikes of SARS-CoV-2 virus which causes COVID-19 are consistent with those of several laboratory-developed protein spikes, designed to mimic the infectious virus.
Engineered cells successfully treat cardiovascular and pulmonary disease
Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.
Novel coronavirus infects and replicates in salivary gland cells
A study conducted at the University of São Paulo suggests that tissues specializing in saliva production and secretion serve as reservoirs for SARS-CoV-2, magnifying its infectious potential.
Diabetes care, glycemic control during pandemic in US
What The Study Did: R ates at which patients with type 2 diabetes received diabetes-related health services prior to and during the COVID-19 pandemic are compared in this study. Authors: Ateev Mehrotra, M.D., M.P.H., of Harvard Medical School in Boston,…
Evaluation of messenger RNA from COVID-19 vaccines in human milk
What The Study Did: COVID-19 v accine-associated messenger RNA (mRNA) wasn’t detected in 13 human milk samples collected after vaccination from seven breast feeding mothers. Authors: Stephanie L. Gaw, M.D., Ph.D., of the University of California, San Francisco, is the…
Seroprevalence, risk factors associated with SARS-CoV-2 infection in health care workers in Italy early in pandemic
What The Study Did: This study in the Lombardy region of Italy examined the association of different health care professional categories and operational units, including in-hospital wards and outpatient facilities, with the seroprevalence of positive IgG antibody tests for SARS-CoV-2…