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UrduPatients with advanced chronic kidney disease (CKD) typically suffer from impaired bone quality and quantity, with a non-vertebral fracture risk which is 4-to 6-fold higher than the fracture risk of matched controls. However, despite their high risk of fragility fractures,…
Tag: ORTHOPEDIC MEDICINE
Personalised 3D printed knee implant could help thousands of arthritis sufferers
Pioneering ‘printed metal’ procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval. World’s first 3D printed high tibial osteotomy (HTO) device and procedure developed at University of Bath given approval…
High-grade acetabular cartilage lesions versus low-grade lesions
Which patients fare better?
Progression to glenohumeral arthritis after arthroscopic posterior stabilization
Nashville, Tenn. (3:24 p.m. EDT–July 10, 2021)–Approximately 12 percent of patients who underwent shoulder stabilization surgery experience arthritis in the shoulder joint within a seven-year period, according to research presented today at the American Orthopedic Society for Sports Medicine-Arthroscopy Association…
Yoga helps reduce work-related stress
Physical relaxation through yoga or other practices can help reduce work-related stress, according to an analysis of studies conducted in healthcare staff. The analysis, which is published in the Journal of Occupational Health , included 15 randomized clinical trials with…
Ulnar collateral ligament injury in gymnasts can be successfully treated
Ulnar Collateral Ligament Injury in Gymnasts: An Analysis of Return to Competition Rates and Patient Outcomes Nashville, Tenn. (1:20 p.m. EDT, July 8, 2021)–In a small study of gymnasts with ulnar (elbow) collateral ligament injury, orthopedic sports medicine researchers found…
Multimodal analgesia: The new ‘standard of care’ for pain control after total joint replacement
July 8, 2021 – Until relatively recently, opioids were a mainstay of treatment for pain following total hip or knee replacement . Today, a growing body of evidence supports the use of multimodal analgesia – combinations of different techniques and…
Muscles retain positional memory from fetal life
New perspectives on the pathological mechanisms of muscle diseases and regenerative medicine development
State of the art and future directions in the clinical application of HR-pQCT in adults
A new international guidance on the clinical application of high-resolution peripheral computed tomography (HR-pQCT) offers an important overview of current clinical applications in adults and direction on the interpretation of results
Osteoporosis: New approach to understanding bone strength pays dividends
Osteoporosis researchers at the UVA School of Medicine have taken a new approach to understanding how our genes determine the strength of our bones, allowing them to identify several genes not previously known to influence bone density and, ultimately, our…
A new reporter mouse line to detect mitophagy changes during muscle tissue loss
Mitophagy reporter mouse could provide cues for future therapies and rehabilitation strategies
Ibuprofen and other NSAIDs superior to codeine for managing outpatient postoperative pain
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen provide better pain control and have fewer adverse effects than codeine, a commonly prescribed opioid, when prescribed after outpatient surgery, according to new research published in CMAJ (Canadian Medical Association Journal) https:/ /…
Calcified Tissue International announces top-cited papers
The authors of the journal’s 10 most oft-cited 2019 papers in 2019-20 have been awarded a certificate of publishing excellence; Get free online access to these notable papers until August 31
Birth weight is associated with osteoporosis risk later in life
New research published in the Journal of Bone and Mineral Research has linked heavier birth weight with lower bone mineral density and a higher risk of bone fracture later in life. The research, which relied on data from the UK…
Osteoarthritis linked to higher Parkinson’s disease risk
A study published in Arthritis Care & Research has uncovered an elevated risk of Parkinson’s disease in individuals with osteoarthritis. The retrospective study using Taiwan’s Longitudinal Health Insurance Database 2005 included 33,360 patients who were 50-64 years old and had…
Study examines care received by patients with knee osteoarthritis
New research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and knee injections, and few were treated by rheumatologists, physiatrists, or pain specialists. The study, which is…
Osteoporosis detection by a simple physical function test
Osteoporosis is a condition that does not exhibit symptoms until there is a bone fracture, so it is said that there is a high percentage of people who remain unaware of their condition. When people are unaware their bones have…
Study supports gene therapy as a promising treatment for soft bone disease
A single dose of AAV8-TNAP-D10 may be safe and effective for hypophosphatasia
Fragility fractures cost European health care systems €56.9 billion annually
New International Osteoporosis Foundation report provides unique overview of osteoporosis in Europe, revealing the enormous disease burden and an unacceptable treatment gap; 71% of women at high risk of fracture are not receiving much-needed medication
New book explores novel techniques in minimally invasive sports medicine procedures
HUNTINGTON, W.Va. – A new book edited by Chad D. Lavender, M.D., an assistant professor of orthopaedic surgery at the Marshall University Joan C. Edwards School of Medicine, explores novel minimally invasive techniques and technology for treating sports medicine and…
MLB ‘FEVER’ — improved elbow MRI view for Major League Baseball pitchers
Flexed elbow valgus external rotation (FEVER) view improves MRI evaluation of ulnar collateral ligament in Major League Baseball throwing athletes
Researchers discover potential new approach to treating psoriatic joint inflammation
(SACRAMENTO, Calif.) – An international team of researchers, led by UC Davis Health , has developed a new therapeutic approach to treating psoriatic arthritis , a chronic inflammatory disease affecting the joints. Using a novel chemical blocker targeting chemokine proteins,…
High-intensity strength and impact training attenuates skeletal aging
The tibial bone properties of middle-aged and older male sprint athletes were followed over 10 years
ALS development could be triggered by loss of network connections in the spinal cord
ALS is a very severe neurodegenerative disease in which nerve cells in the spinal cord controlling muscles and movement slowly die. There is no effective treatment and the average life expectancy after being diagnosed with ALS is usually short. Because…
Blood test detects childhood tumors based on their epigenetic profiles
A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease. The scientists analyzed short fragments of tumor DNA that are circulating in the blood. These “liquid biopsy” analyses exploit the unique epigenetic…
NTU Singapore scientists turn aquaculture waste into new biomaterial for tissue repair
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new biomaterial made entirely from discarded bullfrog skin and fish scales that could help in bone repair. The porous biomaterial, which contains the same compounds that are predominant in…
Hip replacement surgery improves symptoms and biomechanics — but not physical activity
May 27, 2021 – Patients undergoing total hip arthroplasty (THA) show significant reduction in pain and other symptoms and improvement in walking gait biomechanics . However, those improvements do not lead to increased daily physical activity levels, reports a study…
Higher incidence of carpal tunnel syndrome after bilateral oophorectomy
New study suggests the risk of severe carpal tunnel syndrome increases for women after surgery to remove the fallopian tubes and ovaries
Proteomics reveals how exercise increases the efficiency of muscle energy production
Mitochondria are the cell’s power plants and produce the majority of a cell’s energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation. A number of different proteins in mitochondria facilitate these…
New technique breaks the mould for 3D printing medical implants
How to use glue and a high school 3D printer to create tiny implants for tissue engineering
New study shows how to boost muscle regeneration and rebuild tissue
Salk research reveals clues about molecular changes underlying muscle loss tied to aging
In severe ankle arthritis, total ankle replacement yields better function than ankle arthrodesis
May 19, 2021 – For patients with severe arthritis of the ankle , total ankle arthroplasty (TAA) provides better long-term function than ankle arthrodesis (AA), reports a study in The Journal of Bone & Joint Surgery . The journal is…
Total knee replacement may be more painful for vitamin-D deficient postmenopausal women
New study suggests that vitamin D deficiency, smoking, and high body mass index are independent risk factors for increased postoperative pain for postmenopausal women undergoing total knee replacement
How to manage osteoporosis in hematologic stem cell transplant recipients
IOF Cancer & Bone Disease Working Group summary and algorithm outlines main recommendations to maintain bone health in HSCT patients: includes guidance for bone assessment, management and treatment as well as dietary and lifestyle recommendations.
Polymer-based coatings on metallic implants improve bone-implant integration
Polysaccharide and protein-based coatings on metallic implants increase bone tendency to attach on implants, prevent loosening and bacterial invasion
Visio-vestibular examination is critical part of diagnosing concussion in young athletes
CHOP researchers recommend specific updates to clinical examinations to improve initial diagnosis
Urolithin A shows effective against muscular dystrophy
Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today. The findings, published in Science Translational Medicine , raise hopes that new treatment options could one-day…
A common shoulder injury could heal faster, thanks to this first-of-a-kind tissue implant
Longer-lasting rotator cuff repair may be possible with BioEnthesis, a Purdue University invention available on the market
High risk of acute kidney injury in patients undergoing treatment for infected total knee replacement
March 29, 2021 – Acute kidney injury (AKI) occurred in nearly 20 percent of patients who underwent surgery with implantation of antibiotic-loaded “spacers” and intravenous (IV) antibiotics for the treatment of deep infections after total knee arthroplasty , reports a…
Detecting for carpal tunnel syndrome with a smartphone game
Early diagnosis enabled by identifying syndrome based on thumb movements through machine leaning
Scientists use nanotechnology to detect bone-healing stem cells
Researchers at the University of Southampton have developed a new way of using nanomaterials to identify and enrich skeletal stem cells – a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost…
Direct oral anticoagulants show better safety and effectiveness versus warfarin in patients with val
Embargoed news from Annals of Internal Medicine
IFCC-IOF study investigates harmonization of assays for ß-CTX
New study by the IFCC-IOF Committee for Bone Metabolism shows large within- & between-assay variation for ß-CTX measurement; until harmonization is achieved, proposes measuring ß-CTX by the same assay on EDTA plasma, especially for research
Total knee replacement cost effective for patients with osteoarthritis and extreme obesity
Embargoed news from Annals of Internal Medicine
Inflammation and pressure-sensing leads to ‘feed-forward’ loop in osteoarthritis
Cushioning cells in cartilage are reprogrammed in a way that makes things worse
Osteoporosis drug prescribing often does not follow guidelines
Recommended osteoporosis treatment after hip fracture rarely occurs, study finds
Predicting the likelihood of bone fractures in older men
Fractures in the vertebrae of the spine and calcification in a blood vessel called the abdominal aorta can both be visualized through the same spinal imaging test. A new study published in the Journal of Bone and Mineral Research that…
Examining the value of lumbar spine surgery
New prospective clinical study shows that patients have three times greater chance of positive outcomes when their surgeons follow evidence-based guidelines for lumbar spinal fusion
For hip fracture patients, hospital reimbursements rising faster than surgeon reimbursements
March 17, 2021 – In recent years, hospital charges and Medicare payments for patients with hip fractures have increased much more rapidly than charges and payments for orthopaedic surgeons , reports a study in the Journal of Orthopaedic Trauma .…
Telemedicine versus office-based follow-up after meniscal surgery: Trial shows ‘equivalent’ patient satisfaction scores
March 15, 2021 – After arthroscopic surgery on the meniscus of the knee , patients using telemedicine for postoperative follow-up are just as satisfied with their care as those making in-person visits, reports a study in The Journal of Bone…