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UrduNewly-published “contact lens technologies of the future” paper reviews innovative uses for disease detection and therapy, drug delivery, vision enhancement and mor
Tag: IMMUNOLOGY/ALLERGIES/ASTHMA
Analysis of the sensitivity of the UK (B.1.1.7) and South African (B.1.351) variants to SARS-CoV-2
The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries. Scientists from the Institut Pasteur joined forces with Orléans Regional Hospital, Tours University Hospital, Créteil…
Inflammation-fighting protein could improve treatment of rheumatoid arthritis
SPOKANE, Wash. – New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune…
Chronic viral infections can have lasting effects on human immunity, similar to aging
Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C
How much peanut does it take to trigger an allergic reaction?
University of Cincinnati toxicologist says finding an ‘eliciting dose’ may help those who suffer mild or moderate allergic reactions to peanut
Study reveals how long-term infection and inflammation impairs immune response as we age
Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections.
Evidence for reduced antibody protection against SARS-CoV-2 variants
Cell culture studies show that mutated viruses are less susceptible to inhibition by antibodies from recovered or vaccinated individuals
Relieve your stress, relieve your allergies
Osaka City University finds link between the corticotropin-releasing stress hormone and increased expression of allergy-causing mast cells.
SMART develops rapid deterministic lateral displacement assay to assess immune response
Novel DLD assay is capable of rapidly assessing host inflammatory response, allowing patients exhibiting a life-threatening hyper-aggressive immune response to be identified and treated expeditiously
Study reveals how long-term infection and inflammation impairs immune response as we age
HOUSTON, TX – March 25, 2021 – Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. HSCs can either duplicate to produce…
New study published in Science maps wildlife microbiota
Discovering millions of previously unknown potential human therapeutics
Lupus Research Alliance announces awards aimed at new lupus treatments
NEW YORK, March 25, 2021 — The Lupus Research Alliance proudly announces two exceptional recipients of the 2020 Dr. William E. Paul Distinguished Innovator Award in Lupus and Autoimmunity: Jacques Banchereau, PhD and Ignacio Sanz, MD. Both projects funded by…
Scientists identify ‘Goldilocks’ protein critical for getting immune response ‘just right’
Scientists at Sinai Health say they have discovered a new pathway that controls dangerous overreactions in a body’s immune system, including deadly forms of hyper-inflammation. In new findings out today in the journal Science , researchers at the Lunenfeld-Tanenbaum Research…
Pregnant women show robust immune response to COVID vaccines, pass antibodies to newborns
The largest study of its kind to date also found benefit for lactating women
HIV vaccine candidate’s mysteries unlocked 20 years later
Highly effective cytomegalovirus-based vaccine explained in new scientific studies
A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation
This study will aid the understanding of, and future research on, inflammatory bowel disease, which afflicts about 1.6 million Americans
Preservative used in hundreds of popular foods may harm the immune system
New science suggests the FDA should test all food chemicals for safety
Snapshot of COVID-19 vaccine intentions highlights challenges of achieving community immunity goals
Survey fielded in late November and early December suggests half of Americans were either hesitant or unlikely to get vaccinated; findings continue to inform where there’s more work to do
Researchers find cellular evidence behind lasting immune response in some cancer survivors
Researchers at Norris Cotton Cancer Center have found that resident memory T cells that enter a patient’s skin and blood during immunotherapy are behind the excellent and long-lasting immune responses to cancer that some survivors develop.
Survey of Geisinger employees shows increasing acceptance of COVID-19 vaccines
Research also reveals reasons for COVID-19 vaccine hesitancy among healthcare workers
Liver cancer appears to be resistant to immunotherapy in patients with liver condition
Immunotherapy also appears to fuel tumor growth in these cancers
Fatty liver hepatitis is caused by auto-aggressive immune cells
Non-alcoholic steatohepatitis (NASH), often called ‘fatty liver hepatitis’, can lead to serious liver damage and liver cancer. A team of researchers at the Technical University of Munich (TUM) has discovered that this condition is caused by cells that attack healthy…
Patients should receive COVID-19 vaccine before surgery to reduce risk of death
Governments should prioritise surgical patients for COVID-19 vaccination Patients waiting for elective surgery should get COVID-19 vaccines ahead of the general population – potentially helping to avoid thousands of post-operative deaths linked to the virus, according to a new study…
New cancer immunotherapy recruits help from lymphatic vessels
CHICAGO — Immunotherapy, which recruits the body’s own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease. But many cancer immunotherapy treatments can be expensive, have devastating side effects, and only work…
Nanoparticle flu vaccine blocks seasonal and pandemic strains
Scientists at UW Medicine and the NIH have created experimental flu shots that spur broad immunity in animal trials.
Updated Cochrane review assesses how accurate rapid tests are for detecting COVID-19
Today, Cochrane, a global independent network that gathers and summarizes the best evidence from research to help informed health decision-making, publishes an updated systematic review assessing rapid tests for the detection of SARS-CoV-2 infection (COVID-19). The review shows that rapid…
Variances in critical protein may guide fate of those infected with SARS CoV-2
Of the many perplexing questions surrounding SARS CoV-2, a mysterious new pathogen that has killed an estimated 2.6 million people worldwide, perhaps the most insistent is this: why does the illness seem to strike in such a haphazard way, sometimes…
Prolonged immune response may contribute to post-COVID-19 blood clots
COVID-19 survivors, particularly those with heart disease or diabetes, may have an increased risk of blood clots or strokes due to prolonged immune response
Breakthrough in developing new diagnostic procedure for pulmonary aspergillosis
Scientists have developed a pioneering new procedure that will help diagnose a potentially lethal fungal lung disease with greater speed and accuracy, and with less distress to the patient. A team of international scientists, including Professor Chris Thornton from the…
Arsenal used by parasite to affect cellular defense and enhance leishmaniasis is revealed
Group affiliated with a FAPESP-supported research center showed that the parasite blocks the action of an enzyme using autophagy
Containing the coronavirus effects on the nervous system
INRS research could prevent infection of nervous system cells by coronaviruses, such as the one responsible for COVID-19
Delaying 2nd doses of COVID-19 vaccines has benefits, but effects depend on immunity
Researchers analyze projected incidence of COVID-19 cases and degree of immunity of the population
Toronto researchers develop rapid low cost method to measure COVID-19 immunity
New test can accurately detect coronavirus antibodies in a drop of blood in less than an hour
Bacteria may aid anti-cancer immune response
The findings of a new study may explain the microbiome-immunotherapy connection
Study underscores need for multidisciplinary care for COVID-19 long-haulers
Physicians across the country have analyzed the emerging scientific data about the long-term effects of COVID-19, creating an initial knowledge base about the clinical experiences of so-called “long-haulers” – patients with COVID-19 who experience prolonged symptoms and/or the emergence of…
Common inflammatory bowel disease treatment linked to reduced COVID-19 antibody response
New evidence indicates the commonly-prescribed inflammatory bowel disease (IBD) drug infliximab blunts the immune system to COVID-19 infection, potentially increasing the risk of reinfection.
New study implicates disease-driving B cells in fatty liver disease development
University of Minnesota Medical School research suggests a Western diet and changes in gut microbes turn pathogen-fighting B-cells into ‘disease-promoters’
COVID-19: Scientists, doctors launch virtual town halls to address vaccine concerns
More than 50 scientific experts from across the United States, including virologists, infectious disease specialists and medical doctors, are launching a series of virtual town halls to answer the public’s questions about the COVID-19 vaccines. The effort aims to bring…
COVID-19 can cause atypical thyroid inflammation
Study will follow patients to determine if inflammation causes long-term health effects
Supplements may protect those with low vitamin D levels from severe COVID-19
Study finds more than half of patients with low vitamin D do not receive supplements
In pandemic, potentially avoidable hospitalizations for non-COVID conditions fell more among whites
UCLA study suggests new way in which COVID-19 crisis has exacerbated racial health disparities
Important advance in research on future drugs
Most drugs operate via the membranes that surround the body’s cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme that, amongst other things, plays a part in…
Vaccination by inhalation
Delivering vaccines directly to the lungs can boost immune responses to respiratory infections or lung cancer, study finds.
NIH study of early predictors, mechanisms of food allergy and eczema has begun
A study to identify prenatal and early childhood markers of high risk for food allergy and atopic dermatitis, or eczema, as well as biological pathways that lead to these conditions, has begun. The observational study of children from birth to…
High vitamin D levels may protect against COVID-19, especially for Black people
In a retrospective study of individuals tested for COVID-19, vitamin D levels above those traditionally considered sufficient were associated with a lower risk of COVID-19.
Researchers identify immune cells that contribute to transplant rejection
PITTSBURGH, March 19, 2021 – Non-circulating memory T cells, whose main function is to provide local protection against re-infection, contribute to chronic transplant rejection, University of Pittsburgh School of Medicine researchers reveal in a paper published today in Science Immunology.…
HIV: An antidiabetic drug to reduce chronic inflammation
Researchers at the CRCHUM find that metformin could help people living with HIV who are being treated with antiretroviral therapy
Double duty: Gut’s immune system helps regulate food processing, too
The small intestine is ground zero for survival of animals. It is responsible for absorbing the nutrients crucial to life and it wards off toxic chemicals and life-threatening bacteria. In a new study published March 18 in the journal Science…
Targeting a new antibody supersite key to COVID immunity
Antibodies from recovered patients recognize a lesser-known site on the pandemic coronavirus and block infection in lab studies
Study finds inflammatory mechanism responsible for bone erosion in rheumatoid arthritis
In a study of the effects of cigarette smoking on exacerbation of the disease, scientists at a FAPESP-supported research center identified a novel pathway in the inflammatory process relating to bone damage