Below are summaries of recent Fred Hutch Cancer Center research findings, patient stories and other news.
Tag: Hiv Infection
Scientists at The Wistar Institute Clone Several New Anti-Interferon Antibodies – Developing Future Therapeutic Candidates with Broad Application Potential
Wistar Institute scientists have successfully isolated and cloned fully human antibodies that can block specific Type-I interferon molecules in vitro; their discovery has an array of potential clinical & research applications, enabling scientists with a new way to investigate the role of specific Type-I interferons in a variety of diseases.
Study confirms how RNA chemical modifications benefit HIV-1
A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus’s ability to survive and thrive after infecting host cells, a new study has found.
Gut bacteria may contribute to susceptibility to HIV infection, UCLA-led research suggests
New UCLA-led research suggests certain gut bacteria — including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected. The findings, published in the peer-reviewed journal eBioMedicine, suggest that the gut microbiome could contribute to one’s risk for HIV infection, said study lead Dr.
Researchers Receive $4.2M Grant to Improve PrEP Access and Prevent New HIV Infections
Bronx county has the country’s fifth-highest rate of HIV diagnosis—but the lowest rate in New York State for use of HIV pre-exposure prophylaxis (PrEP), medications that are extremely effective in preventing HIV infection. Physician-researchers at Albert Einstein College of Medicine and Montefiore Health System have received a five-year, $4.2 million grant from the National Institutes of Health to compare two strategies for improving PrEP access and use in the Bronx.
Neuroscientists identify how the brain links related memories
UCLA scientists have discovered how the brain links memories and a way to restore this function in aging mice–as well as an FDA-approved drug that achieves the same thing. The Nature findings suggest a new method for combatting middle-aged memory loss.
Discovery of cell protein that keeps Kaposi’s sarcoma herpesvirus dormant
A study led by UC Davis Cancer Center identified a binding protein in cancer cell’s nucleus, known as CHD4, as a critical agent keeping Kaposi’s sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body’s immune system. CHD4 is linked to cancer cell growth in many types of cancers.