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UrduA UCLA-led team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, possibly leading to new therapies for heart disease and cardiac damage.
Tag: Heart Damage
Professor and students seek to uncover Nature’s chilling secret
Eric Bredahl, PhD, and his team of undergraduate research assistants are trusting that Nature, if asked nicely, or at least insistently, will yield another of her secrets.
Researchers Look at Role of Potassium Channels in Sirtuin-mediated Cardioprotection
Article title: The cardioprotective role of sirtuins is mediated in part by regulating KATP channel surface expression Authors: Erkan Tuncay, Ivan Gando, Jian-Yi Huo, Gautham Yepuri, Natalie Sampler, Belma Turan, Hua-Qian Yang, Ravichandran Ramasamy, William A. Coetzee From the authors: “Overall,…
Cause of heart damage from cancer drugs identified
Safer cancer drugs are now one step closer after a new study led by UCL (University College London) researchers found the likely reason that some treatments damage the heart.
How a SARS-CoV-2 Virus Protein Damages the Heart
Researchers at the University of Maryland School of Medicine’s (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.
Stress Testing Can Help Determine Which Patients Are Likely to Benefit From Heart Procedures to Improve Survival
Mount Sinai study can help guide proper treatment course for patients depending on heart function and severity of heart damage
COVID-19 can kill heart muscle cells, interfere with contraction
A new study from Washington University School of Medicine in St. Louis provides evidence that COVID-19 patients’ heart damage is caused by the virus invading and replicating inside heart muscle cells, leading to cell death and interfering with heart muscle contraction. The researchers used stem cells to engineer heart tissue that models the human infection and could help in studying the disease and developing possible therapies.
Bone Marrow SPARC Protein Production Causes Fibrosis in Mouse Hearts
Article title: SPARC production by bone marrow-derived cells contributes to myocardial fibrosis in pressure overload Authors: Hannah J. Riley, Ryan R. Kelly, An O. Van Laer, Lily S. Neff, Shaoni Dasgupta, Catalin F. Baicu, Lindsay T. McDonald, Amanda C. LaRue,…
Finding a way to stop chemotherapy from damaging the heart
There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.
Mount Sinai Cardiologist Awarded $2.9 Million NIH Grant to Advance Work with Stem Cells and Heart Repair after Heart Attack
Research may lead to identifying novel therapies for cardiac patients
Smidt Heart Institute Launches Clinic to Treat Heart Damage in COVID-19 Survivors
The Smidt Heart Institute at Cedars-Sinai has established a specialized cardiac clinic to care for COVID-19 survivors who may be subject to long-term heart damage. Experts available for interviews in English and Spanish; HD video is available upon request.
Ultrasounds Show Impact of COVID-19 on the Heart
International study may guide therapeutic strategies in patients with and without underlying heart conditions
Heart Injury Among Hospitalized COVID-19 Patients Associated with Higher Risk of Death
Study findings may help doctors better triage coronavirus patients admitted to the hospital
Cheaper Drug Just As Effective Protecting Heart in Duchenne Muscular Dystrophy
A new clinical trial conducted at The Ohio State University Wexner Medical Center found a cost-effective generic medication works just as well as a more expensive drug in preserving cardiovascular function in boys with Duchenne muscular dystrophy (DMD).
Hearts and Stripes: A Tiny Fish Offers Clues to Regenerating Damaged Cardiac Tissue
Zebrafish and mammals share key cellular features; researchers have identified how the former repair their damaged hearts and now wonder if humans might someday be able to do so, too Research into the hearts of zebrafish, a pet shop staple…