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UrduResearchers at Keck School of Medicine of USC identify a novel target related to the blood-brain barrier and a potential therapy that offers hope for slowing progression of Alzheimer’s disease in people with the APOE4 gene
Tag: genes
Largescale brain epigenetics study provides new insights into dementia
The largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linked to the disease.
LIM domain only 1: One gene, many roles in cancer
Researchers detail another gene target that could be the crucial link to curing different cancers
Study identifies how COVID-19 linked to Alzheimer’s disease-like cognitive impairment
Cleveland Clinic-led research team used artificial intelligence to uncover association between COVID-19 and brain changes
How cells measure themselves
Ever since scientists discovered cells under the microscope more than 350 years ago, they have noted that each type of cell has a characteristic size. From tiny bacteria to inches-long neurons, size matters for how cells work. The question of…
Scientists uncover the mysteries of how viruses evolve
Scientists uncover the mysteries of how viruses evolve
Preliminary genetic link to developmental coordination disorder, dyspraxia identified
New research by scientists at Oxford Brookes University has identified specific genes which could provide vital information about the biology of developmental coordination disorder (DCD), also known as dyspraxia. Dyspraxia is a common motor coordination condition which is estimated to…
Scientists use public databases to leap over scourge of publication bias
Scientists have leapt over the emerging problem of publication bias within genetic research by performing a meta-analysis of publicly available databases of ‘transcriptomes’, or the full range of messenger RNA molecules produced by an organism. Researchers from Hiroshima University applied…
SARS-CoV-2 protease cuts human proteins; possible link to COVID-19 symptoms
The SARS-CoV-2 papain-like protease (PLpro) plays an essential role in processing viral proteins needed for replication. In addition, the enzyme can cut and inactivate some human proteins important for an immune response. Now, researchers reporting in ACS Infectious Diseases have…
Advancing manufacture of cell and gene therapies webinar
An ECI webinar on July 21, 2021
Breast cancer risk in African-Americans tied to genetic variations
Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The study…
Experiments show natural selection opposes sexual selection
Natural selection can reverse evolution that occurs through sexual selection and this can lead to better females, new research shows. The study – led by the University of Exeter and Okayama University – examined broad-horned flour beetles, whose males have…
Researchers identify gene linked to congenital heart disease
Researchers have identified a gene that plays a minor role in congenital heart disease, using a combined approach that could aid studies of this and other multigenic diseases
A mechanism through which ‘good’ viruses kill ‘bad’ bacteria and block their reproduction
An important step in the battle against antibiotic-resistant bacteria
Measuring gene expression changes over time may help predict T1D diabetes progression
An international research team, including the University of South Florida Health Informatics Institute, created and validated a predictive model with potential for early monitoring of infants at risk for type 1 diabetes
Fruit fly links sleep problems in autism to glial cells, blood-brain-barrier and serotonin
Bad sleep causes severe health issues and affects our ability to concentrate, memorize, and cope with challenging situations. Individuals with neurodevelopmental disorders such as autism and intellectual disability, frequently suffer from sleep problems. However, little is known about their underlying…
Research advances one step closer to stem cell therapy for type 1 diabetes
Salk research shows how to optimize the production of insulin-producing cells from stem cells
A Computational Look at How Genes Change the Human Brain
Pitt Engineer’s research will focus on better understanding the mechanisms behind Alzheimer’s disease and other neurological disorders
The 8th International Horticulture Research Conference Announcement
To showcase the latest achievements and research progress in the field of horticulture, and promote communication and cooperation among world experts, the 8th International Horticulture Research Conference will be held from July 20 to 22, 2021 in Nanjing, China, and…
Puppies are born ready to communicate with people, study shows
Anyone that’s ever interacted with a dog knows that they often have an amazing capacity to interact with people. Now researchers reporting in the journal Current Biology on June 3 have found that this ability is present in dogs from…
No evidence that the shift to farming made males and females more physically similar
Genomic study finds that natural selection is not changing the size and shape of the sexes
Expression of ‘fat’ genes correlate with metabolic, behavioral changes linked to obesity
New study identifies a constellation of genetic variants in FTO, which in turn influence expression of IRX3 and IRX5, collectively mediating risk of obesity
Elevating African cichlid fish as a scientific model of social disorders
University of Houston researcher wins prestigious Beckman Young Investigator Award
Biomarker predicts bowel cancer recurrence
A biomarker in the blood of patients with bowel cancer may provide valuable insight into the risk of cancer relapse after surgery and the effectiveness of chemotherapy. Research published in PLOS found circulating tumour DNA (ctDNA) measured before and after…
Target protein identified for improving heart attack treatment
A new study led by researchers at Washington State University has identified a protein that could be the key to improving treatment outcomes after a heart attack. Published in the Journal of Biological Chemistry , the research suggests that protein…
Regulation of the genome affects its 3D structure
All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell “reads” different chapters of the genome, thus producing alternative sets of proteins and embarking on…
Researchers figured out how the ancestors of modern horses migrated
Molecular biologists studied the DNA of ones that migrated from North America to Eurasia and back
The Varroa mite dsRNA is not toxic to monarch butterflies
The Varroa mite dsRNA which could help save honeybees is not toxic to monarch butterflies, despite them having the same target gene as the mite
Male piglets less resilient to stress when moms get sick during pregnancy
URBANA, Ill. -When pigs get hit with significant illnesses during key stages of pregnancy, their immune response may negatively affect developing piglets, making them less productive on the farm. New research from the University of Illinois shows that when those…
Unprecedented data sharing driving new rare disease diagnoses in Europe
Results are just ‘tip of the iceberg’, according to researchers
Researchers discover how cells can survive in high salt concentrations
Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a…
Mass of human chromosomes measured for the first time
The mass of human chromosomes, which contain the instructions for life in nearly every cell of our bodies, has been measured with X-rays for the first time in a new study led by UCL researchers.
Researchers report reference genome for maize B chromosome
Three groups (Dr. James Birchler’s group from University of Missouri, Dr. Jan Barto’s group from Institute of Experimental Botany of the Czech Academy of Sciences and Dr. HAN Fangpu’s group from the Institute of Genetics and Developmental Biology of the…
Scientists discover a new genetic form of ALS in children
NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy
Ethnic diversity helps identify more genomic regions linked to diabetes-related traits
By including multi-ethnic participants, a largescale genetic study has identified more regions of the genome linked to type 2 diabetes-related traits than if the research had been conducted in Europeans alone.
Scientists call for international investment to tackle major wheat losses
Urgent investment in new tools is needed to address major global losses of wheat crops which cost £22 billion per year. Leading scientific experts are calling for governments around the world to come together and fund a new international research…
Study sheds light on population history of northern east Asia
A study led by research groups of Prof. FU Qiaomei from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences and Prof. ZHANG Hucai from Yunnan University covers the largest temporal transect of population dynamics…
Microbial gene discovery could mean greater gut health
URBANA, Ill. – As the owner of a human body, you’re carrying trillions of microbes with you everywhere you go. These microscopic organisms aren’t just hitching a ride; many of them perform essential chemical reactions that regulate everything from our…
UVA develops new tools to battle cancer, advance genomics research
University of Virginia School of Medicine scientists have developed important new resources that will aid the battle against cancer and advance cutting-edge genomics research. UVA’s Chongzhi Zang, PhD, and his colleagues and students have developed a new computational method to…
Ultrafast, on-chip PCR could speed diagnosis during current and future pandemics
Reverse transcription-polymerase chain reaction (RT-PCR) has been the gold standard for diagnosis during the COVID-19 pandemic. However, the PCR portion of the test requires bulky, expensive machines and takes about an hour to complete, making it difficult to quickly diagnose…
Immune function of small chloroplasts in the epidermal cells of plants
It is said that 10 to 15% of the world’s agricultural production loss is caused by diseases, which is equivalent of the food for about 500 million people. And since 70-80% of this plant disease is caused by filamentous fungi,…
Scientists discover a protein that naturally enhances wheat resistance to head scab
Fusarium Head Blight (FHB), also known as scab, is a significant disease of small grain cereals, such as wheat and barley, that impacts farmers around the world. The disease has been reducing acreage and increasing the price of wheat production…
Cocaine’s effect on the brain: Fruit fly research shows impact at the cellular level
Study lays groundwork for developing drugs to treat or prevent addiction in humans and provides contextual framework for future research
Unforeseen links to chronic pancreatitis found in cancer-related signals
Researchers at Osaka University reveal the molecular mechanisms that underlie the development and progression of chronic pancreatitis and identify a therapeutic target for further research
New study shows how to boost muscle regeneration and rebuild tissue
Salk research reveals clues about molecular changes underlying muscle loss tied to aging
Virus infection cycle revealed in dynamic detail
A critical process in the infection cycle of viruses has been revealed for the first time in dynamic detail using pioneering plant-based technology. Evidence about the process of virus maturation revealed in the research could help us develop new methods…
How tendons become stiffer and stronger
Tendons are what connect muscles to bones. They are relatively thin but have to withstand enormous forces. Tendons need a certain elasticity to absorb high loads, such as mechanical shock, without tearing. In sports involving sprinting and jumping, however, stiff…
Chemical changes to peptide siRNA-carrier enhance gene silencing for future cancer drugs
MUSC Hollings Cancer Center researchers improve peptide siRNA drug carriers for use as a novel cancer treatment
How do clownfish earn their stripes?
The distinctive white stripes in clownfish form at different rates depending on their sea anemone hosts, a PNAS study finds
Full-genome CRISPR screen reveals surprising ways neurons survive oxidative stress
When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of the cell. In a new study appearing May 24 in Nature Neuroscience , UCSF researchers have…