An international consensus panel, led by WIMR researchers, has highlighted the need to redefine non-alcoholic fatty liver disease
Tag: Gastroenterology
Loss of protein disturbs intestinal homeostasis and can drive cancer
Colorectal carcinoma (CRC), the most common form of intestinal cancer, is the second leading cause of cancer related death worldwide. While some patients have a genetic predisposition to the disease, the majority of cases are sporadic and largely influenced by…
MAFLD: A new name and definition brings hope for patients with fatty liver disease
An international consensus panel, led by WIMR researchers, has highlighted the need to redefine non-alcoholic fatty liver disease
New COVID-19 info for gastroenterologists and patients
New paper published in Clinical Gastroenterology and Hepatology outlines key information for gastroenterologists and patients with chronic digestive conditions
Data from Sweden used to examine PPI use, risk of fracture in children
What The Study Did: Data from Sweden were used to compare 115,933 pairs of children who did or didn’t use proton pump inhibitors (PPIs) to examine the association between PPI use and risk of fracture in children. Author: Yun-Han Wang,…
Solving obesity: Could manipulating microbes offer an alternative to weight loss surgery?
Already considered a global epidemic, human obesity continues to be on the rise. According to the Centers for Disease Control, more than 40% of the U.S. population is considered obese. The gamut of adverse health effects associated with obesity is…
Immunosuppressive therapy for inflammatory bowel disease does not increase women’s risk of vulvar or vaginal cancer
However significantly earlier onset of vulvovaginal malignancies in IBD patients, compared with the general population, is reported by researchers in Digestive and Liver Disease
Comparing risk of colorectal cancer after weight-loss surgery
What The Study Did: Researchers used French electronic health data to investigate how risk of colorectal cancer compared among obese adults who had weight-loss surgery and who didn’t. Authors: Laurent Bailly, M.D., Ph.D., Universite Cote d’Azur, Nice, France, and coauthors.…
Study reveals rising colorectal cancer rates among young adults
A population-based analysis from England indicates that the incidence of colorectal cancer is increasing rapidly in young adults.
March 2020 Issue of The American Journal of Gastroenterology Includes Complementary & Alternative Therapies for Functional GI Disorders
The March issue of The American Journal of Gastroenterology features evidence-based articles related to complementary and alternative medicine therapies for functional GI disorders, a new ACG Clinical Guideline for the diagnosis and management of Chronic Pancreatitis, opioid-related constipation, and more.
Mayo Clinic-led study links obesity with pancreatitis
PHOENIX — A study by researchers at Mayo Clinic in Arizona published in the the Journal of Clinical Investigation has found that obesity is not only implicated in chronic diseases such as diabetes, but also in sudden-onset diseases such as…
GI symptoms and potential fecal transmission in coronavirus patients
Gastroenterology publishes two studies describing gastrointestinal manifestations and potential for fecal-oral transmission
Two-faced bacteria
Texas A&M researchers discover previously unknown response within gut microbiota
GI symptoms and potential fecal transmission in coronavirus patients
Gastroenterology publishes two studies describing gastrointestinal manifestations and potential for fecal-oral transmission
Two-faced bacteria
Texas A&M researchers discover previously unknown response within gut microbiota
Using artificial intelligence to assess ulcerative colitis
Researchers from Tokyo Medical and Dental University (TMDU) develop an artificial intelligence system that effectively evaluates endoscopic mucosal findings from patients with ulcerative colitis without the need for biopsy collection Tokyo, Japan – Assessments of patients with ulcerative colitis (UC),…
Electrical stimulation helps treat constipation in clinical trial
Electrical stimulation benefited women with constipation in a recent clinical trial published in Alimentary Pharmacology & Therapeutics . In the trial, 33 women with constipation that had not improved with standard treatment received either real or sham electrical stimulation on…
Weight loss surgery may increase fracture risk
Individuals who undergo weight loss surgery may face an elevated risk of bone fractures, according to a study published in the Journal of Internal Medicine . The study included 2,007 Swedish patients with obesity who were treated with weight loss…
Electrical stimulation helps treat constipation in clinical trial
Electrical stimulation benefited women with constipation in a recent clinical trial published in Alimentary Pharmacology & Therapeutics . In the trial, 33 women with constipation that had not improved with standard treatment received either real or sham electrical stimulation on…
Weight loss surgery may increase fracture risk
Individuals who undergo weight loss surgery may face an elevated risk of bone fractures, according to a study published in the Journal of Internal Medicine . The study included 2,007 Swedish patients with obesity who were treated with weight loss…
CHOP Researchers Develop Novel Approach to Capture Hard-to-View Portion of Colon in 3-D for the First Time
In a groundbreaking discovery, researchers at Children’s Hospital of Philadelphia (CHOP) developed a new imaging method that allows scientists to view the enteric nervous system (ENS) – a key part of the human colon – in three dimensions by making other colon cells that normally block it invisible. The ENS has previously only been visible in thin tissue slices that provide limited clinical information.
Celiac disease might be cured by restoring immune tolerance to gliadin
Celiac disease affects 0.3-2.4% of people in most countries world-wide, and approx. 2% in Finland. Celiac patients suffer from a variety of symptoms, typically intestinal complaints, such as diarrhea, but are often symptom-free. Immunologist Tobias Freitag co-developed and tested nanoparticles…
CHOP researchers develop novel approach to capture hard-to-view portion of colon in 3D
New imaging technique of the body’s ‘second brain’ will allow doctors to help patients with diseases involving the colon’s enteric nervous system
Genetic ‘fingerprints’ implicate gut bacterium in bowel cancer
A common type of bacteria found in our guts could contribute to bowel cancer, according to research funded by a £20 million Cancer Research UK Grand Challenge award and published in Nature today (Thursday)*. Scientists in The Netherlands, the UK…
Celiac disease might be cured by restoring immune tolerance to gliadin
Celiac disease affects 0.3-2.4% of people in most countries world-wide, and approx. 2% in Finland. Celiac patients suffer from a variety of symptoms, typically intestinal complaints, such as diarrhea, but are often symptom-free. Immunologist Tobias Freitag co-developed and tested nanoparticles…
CHOP researchers develop novel approach to capture hard-to-view portion of colon in 3D
New imaging technique of the body’s ‘second brain’ will allow doctors to help patients with diseases involving the colon’s enteric nervous system
Genetic ‘fingerprints’ implicate gut bacterium in bowel cancer
A common type of bacteria found in our guts could contribute to bowel cancer, according to research funded by a £20 million Cancer Research UK Grand Challenge award and published in Nature today (Thursday)*. Scientists in The Netherlands, the UK…
Potential New Heartburn Drug Studied at VUMC
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.
How Resident Microbes Restructure Body Chemistry
A comparison of normal and germ-free mice revealed that as much as 70 percent of a mouse’s gut chemistry is determined by its gut microbiome. Even in distant organs, such as the uterus or the brain, approximately 20 percent of molecules were different in the mice with gut microbes.
Structural framework for tumors also provides immune protection
Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report. Immune checkpoints found throughout the body are intended to protect your body from being attacked by your immune system. But in…
Structural framework for tumors also provides immune protection
Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report. Immune checkpoints found throughout the body are intended to protect your body from being attacked by your immune system. But in…
How resident microbes restructure body chemistry
As much as 70% of the molecules in a mouse are determined by the microbes that live within the animal
Potential new heartburn drug studied at VUMC
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests. Michael F. Vaezi,…
How resident microbes restructure body chemistry
As much as 70% of the molecules in a mouse are determined by the microbes that live within the animal
Potential new heartburn drug studied at VUMC
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests. Michael F. Vaezi,…
Ancient gut microbiomes shed light on human evolution
The microbiome of our ancestors might have been more important for human evolution than previously thought, according to a new study published in Frontiers in Ecology and Evolution.
Ancient gut microbiomes shed light on human evolution
A new study on the microbiomes of our ancestors offers hypotheses about the influence of microbes on our early social and daily lives
GI societies issue updated colorectal cancer screening recommendations
Patients at average risk of colorectal cancer who have a normal colonoscopy do not need to repeat screening for 10 years.
GI societies issue updated colorectal cancer screening recommendations
Bethesda, Maryland (Feb. 18, 2020) – Patients at average risk of colorectal cancer who have a normal colonoscopy do not need to repeat screening for 10 years. It is common for polyps to be removed and tested during a colonoscopy,…
Low folate levels can indicate malnutrition in hospital patients
About 10% of patients who come to complex care hospitals may have low levels of folate and other indicators of malnutrition, investigators say. To ensure those patients are identified and helped, those who present with gastrointestinal problems, chronic kidney disease…
Trust your gut on plant-based diets for heart health
Adhering to a gut-healthy plant-based diet over animal products may counteract unfavorable microbes known to increase heart disease risk
AGA announces new journal Techniques and Innovations in Gastrointestinal Endoscopy
The newest addition to the AGA journal family will focus on advances in endoscopic procedures
Poop matters: Making the mouse gut microbiome more human-like
There is a growing consensus that the gut microbiome is involved in many aspects of physical and mental health, including the onset of Parkinson’s disease, multiple sclerosis, and even some behaviors. The microbiota of the small intestine in particular are…
AGA announces new journal Techniques and Innovations in Gastrointestinal Endoscopy
The newest addition to the AGA journal family will focus on advances in endoscopic procedures
Study: Bariatric surgeries can double peak blood alcohol levels, patients may be unaware
CHAMPAIGN, Ill. — A new study of 55 women found that two of the most popular forms of bariatric surgery – Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy – may dramatically change patients’ sensitivity to and absorption of alcohol. Some…
Poop matters: Making the mouse gut microbiome more human-like
There is a growing consensus that the gut microbiome is involved in many aspects of physical and mental health, including the onset of Parkinson’s disease, multiple sclerosis, and even some behaviors. The microbiota of the small intestine in particular are…
Study: Bariatric surgeries can double peak blood alcohol levels, patients may be unaware
CHAMPAIGN, Ill. — A new study of 55 women found that two of the most popular forms of bariatric surgery – Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy – may dramatically change patients’ sensitivity to and absorption of alcohol. Some…
What would it take to make FMT mainstream? Two publications consider the opportunities
Many of the microbes that live in your gut are also found in your stool, and fecal microbiota transplants (FMTs) are being studied to determine whether they can improve health outcomes in patients with various diseases such as ulcerative colitis…
NETRF funds $3.5 million in research to advance neuroendocrine tumor treatment
The Neuroendocrine Tumor Research Foundation (NETRF), Boston, MA, today announced $3.5 million in neuroendocrine tumor (NET) research grants to fund 12 projects around the world in pursuit of more precise treatments for this uncommon cancer affecting an estimated 171,000 Americans.…
What would it take to make FMT mainstream? Two publications consider the opportunities
Many of the microbes that live in your gut are also found in your stool, and fecal microbiota transplants (FMTs) are being studied to determine whether they can improve health outcomes in patients with various diseases such as ulcerative colitis…