Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
Tag: Cas9
GW Wins Contract to Develop Antidote-Bearing Organisms to Protect Against Biological, Chemical Threats
The George Washington University has been awarded a $3.6 million contract to genetically modify commensal organisms to produce antidotes for harmful biological and chemical agents, such as anthrax, Ebola, and even COVID-19.
UC San Diego Scientists Develop the First CRISPR/Cas9-based Gene Drive in Plants
Researchers have created the first CRISPR-Cas9-based gene drive designed for plants. The new technology, which allows scientists to cut and copy key genetic elements, helps scientists breed plants that defend against crop diseases and withstand the impacts of climate change.
Scientists Use DNA Origami to Monitor CRISPR Gene Targeting
ROCKVILLE, MD – The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target.
Advancing Gene Editing With New CRISPR/Cas9 Variant
Researchers report the ability to improve safety and efficacy using a CRISPR-Cas9 variant known as miCas9.
The Gut Microbiome, CRISPR/Cas-9, and More Featured in August 2020 Toxicological Sciences
The August 2020 issue of Toxicological Sciences includes exciting advances in toxicology research. The edition features pieces on biotransformation, toxicokinetics, and pharmacokinetics; developmental and reproductive toxicology; and more.
Xenobiotic Receptor Activation, CRISPR/Cas9, Magnetic Resonance-Guided Radiotherapy, and More Featured in May 2020 Toxicological Sciences
During these difficult times, the Society of Toxicology’s official journal, Toxicological Sciences, remains a source for leading research in toxicology, including in the areas of biomarkers, carcinogenesis, and organ-specific toxicology.