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UrduATLANTA –New research found that the 30-day death rate for Medicaid patients with systemic lupus erythematosus (SLE) who underwent coronary revascularization procedures for cardiovascular disease was double that of patients with diabetes mellitus who underwent the same procedures. This study…
Tag: MEDICINE/HEALTH
Additional medications to treat children with JIA are urgently needed
ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, there is a profound ongoing need for additional medications to control the signs and symptoms of juvenile idiopathic arthritis (JIA), despite the availability of…
Tocilizumab more effective than Rituximab in RA patients with low B-cell levels
ATLANTA –New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying…
Babies exposed to TNFi or tofacitinib in utero experience very few serious infections
ATLANTA — A new study found that very few serious infections were seen in children born to mothers with chronic inflammatory diseases who used non-TNFi biologics or tofacitinib during pregnancy compared to children not exposed to these drugs and children…
Ultrasound to guide treatment strategy not beneficial in early RA
ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, a treatment strategy guided by ultrasound information use does not appear to provide better treatment decisions in patients with early rheumatoid arthritis . The…
Biologics offer similar disease activity improvement for elderly & young-onset RA patients
ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, both patients with rheumatoid arthritis whose disease onset occurred at an older age and those whose disease onset occurred earlier in life have similar…
Hospitalizations among dialysis patients are higher in areas with more black residents
Washington, DC (November 9, 2019) — Patients with kidney failure who receive hemodialysis at US clinics located in residential areas with a high percentage of Black residents are more likely to be hospitalized than those who receive hemodialysis in communities with…
Children with Down syndrome at increased risk for inflammatory, erosive arthritis
ATLANTA –A new study finds that children with Down syndrome are at an increased risk of an associated form of arthritis. Additionally, researchers recommend changing the name to Down syndrome-associated arthritis to more accurately reflect the inflammatory and erosive nature…
Rising rates of kidney injury in women who are hospitalized during pregnancy
Washington, DC (November 9, 2019) — A recent analysis reveals increasing rates of acute kidney injury in women who are hospitalized during pregnancy, especially among those with diabetes. Also, women with pregnancy-related acute kidney injury were much more likely to…
Down syndrome arthropathy diagnosis delayed a year, optimal treatments still unclear
ATLANTA –A new study found that patients with Down syndrome arthropathy continue to have an approximate year-long delay in diagnosis from the onset of their symptoms, and that optimal therapy for this condition remains unclear (Abstract # 2722 ). Details…
Examining muscle relaxant dose, risk of encephalopathy in patients with CKD
What The Study Did: Whether a higher or lower dose of the muscle relaxant baclofen was associated with 30-day risk of hospitalization with encephalopathy (defined as a main diagnosis of delirium, disorientation, transient alteration of awareness, transient ischemic attack or…
Gadolinium-enhanced MRI improves diagnostic accuracy and predicts polymyalgia rheumatica
ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, use of gadolinium-enhanced magnetic resonance imaging (MRI) in shoulders of patients with polymyalgia rheumatica may contribute to more accurate diagnosis and prediction of recurrence.…
Common muscle relaxant causes severe confusion in patients with kidney disease
One in 25 patients with very low kidney function were admitted to hospital with severe confusion and other cognitive-related symptoms a few days after being prescribed a common muscle relaxant. A new study from ICES Western, Western University and Lawson…
Limited access to SLE lab tests in developing nations affects usefulness
ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, supportive laboratory assays to diagnose lupus, specifically the antinuclear antibody (ANA) test, are less often offered in developing nations due to a relative lack…
Low-dose oral prednisolone substantially improves pain and function in hand OA
ATLANTA — Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis ( Abstract #1760 ). Osteoarthritis (also known…
Live zoster vaccine safe and effective for people taking TNF inhibitors
ATLANTA — According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications (Abstract…
Methotrexate reduces joint damage progression over placebo in erosive hand OA
ATLANTA — According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but…
Opioids offer minor pain relief and function benefits, but no quality of life benefit
ATLANTA –New research presented at the 2019 ACR/ARP Annual Meeting suggests that opioids contribute no measurable benefit to quality of life or depression for patients with osteoarthritis (OA). Researchers also found only small benefits on pain and function after two…
Opioid use hospitalization rates increased for patients with common rheumatic diseases
ATLANTA — New research findings presented this week at the 2019 ACR/ARP Annual Meeting show an increase in opioid-use disorder (OUD) hospitalizations among patients with five musculoskeletal conditions, trends that healthcare providers, policy makers and patients need to be more…
Study points to new weapon in fight against lethal fungi
Monash University researchers have gained insights into how nanoparticles could develop a biosensor to prevent deadly diseases contracted on medical equipment, such as catheters. Candida albicans can become a serious problem for people who are seriously ill or immune-suppressed. Researchers…
Psoriasis onset determines if psoriatic arthritis patients develop arthritis or psoriasis first
ATLANTA — In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found that the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis . Additionally, they found that pustular psoriasis…
American Society of Nephrology honors leaders in the fight against kidney diseases
Awards recognizing contributions to research, education, and clinical practice will be presented at ASN Kidney Week 2019
Post-market price changes alone account for most recent spending growth for biologics
ATLANTA — New research findings presented at the 2019 ACR/ARP Annual Meeting found that annual spending on biologic DMARDS (biologics) by U.S. public programs and beneficiaries nearly doubled from 2012 to 2016. The study showed post-market drug price changes alone…
Air pollution in India is associated with higher risk of cardiovascular disease
The association between ambient and household air pollution and carotid intima-media thickness (CIMT), a marker of atherosclerosis, has been explored for the first time in a population of a low-and-middle income country by a team led by the Barcelona Institute…
Did vitamin D, Omega-3 supplements help prevent development, progression of CKD in adults with type 2 diabetes?
What The Study Did: Researchers in this randomized clinical trial investigated if supplementation with vitamin D or omega-3 fatty acids compared with placebo over five years helped prevent the development or progression of chronic kidney disease among adults with type…
Study finds brains of girls and boys are similar, producing equal math ability
New research at Carnegie Mellon University indicates that there is no gender disparity in how children learn and perform math skills
Predicting risk of chronic kidney disease
What The Study Did: Data from about 5 million people (with and without diabetes) in 28 countries were used to develop equations to help identify people at increased five-year risk of chronic kidney disease, defined as reduced estimated glomerular filtration…
World’s first AI-powered ultrasound guided automated spinal landmark identification
Study shows that world’s first AI-powered ultrasound guided automated spinal landmark identification system increases accuracy and success rate of first-attempt needle insertion in spinal anaesthesia
Depressed MS-patients suffer debilitating symptoms earlier
People with multiple sclerosis (MS) who also have depression are more likely to suffer debilitating symptoms early than people with MS who are not depressed, according to a study at Karolinska Institutet in Sweden that is published in the journal…
Stress hormone helps control the circadian rhythm of brain cells
As day turns into night, and night turns into day, the vast majority of living organisms follow a fixed circadian rhythm that controls everything from sleep needs to body temperature. This internal clock is found in everything from bacteria to…
Study shows biomarker accurately diagnoses deadly infant disease
New Orleans, LA – A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis (NEC). Led by researchers and…
What you don’t know about these cute animals could harm you (video)
WASHINGTON, Nov. 08, 2019 — Don’t let their cuteness fool you — these animals are not to be messed with. This week on Reactions, we break down the chemistry behind what makes these adorable critters deadly: https:/ / youtu. be/…
Doctors don’t realize hair care prevents many African-American women from exercise
Education needed to help doctors work with patients, find solutions to stay active
Oral health for older adults
Research summary from the Journal of the American Geriatrics Society
Genetic diversity facilitates cancer therapy
Cancer patients with more different HLA genes respond better to treatment
High-impact clinical trials yield results that could improve kidney care
Washington, DC (November 8, 2019) — The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented at ASN Kidney Week 2019 November 5-November 10 at the Walter E. Washington Convention Center in Washington, DC.…
Study vaccine protects monkeys against four types of hemorrhagic fever viruses
WHAT: Scientists funded by the National Institutes of Health have developed an investigational vaccine that protected cynomolgus macaques against four types of hemorrhagic fever viruses endemic to overlapping regions in Africa. The University of Texas Medical Branch in Galveston and…
Investigators build a better targeted drug therapy using the power of computation
Team designs LEGO-like linkers that can stably click a drug payload to an antibody that can bind to tumor tissue with specificity
Leading risk factors, causes of death underrepresented in NIH-supported prevention research
Study finds leading risk factors and causes of death and disability underrepresented in NIH-supported prevention research
High numbers of youth report using prescription opioids in the past year
Results from national survey on drug use and health for 2015-2016
Regenstrief playing major role in nationwide effort to improve care for dementia patients
Brown University and Hebrew SeniorLife leading research incubator
Kidney disease outcomes differ between severely obese kids vs. adults after bariatric surgery
WASHINGTON – Adolescents with Type 2 diabetes experienced more hyperfiltration and earlier attenuation of their elevated urine albumin-to-creatinine ratio (UACR) after gastric bypass surgery compared with adults. This finding contrasts with adolescents or adults who did not have diabetes prior…
TTUHSC researchers publish preclinical data on new drug combination to treat neuroblastoma
Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most…
Study finds glutamates such as MSG can help reduce Americans’ sodium intake
Promising results from a new study published in the journal Nutrients add to accumulating evidence that glutamates such as monosodium glutamate (MSG) can be used to reduce sodium in the food supply. The study analyzed data from the National Health…
University of Cincinnati finds new option for liver transplant patients
Common drug offers fewer side effects than prednisone, but similar organ rejection rates in liver transplants in preliminary studies
Best practice treatment guidelines help doctors identify, treat vaping-associated lung injuries
As the outbreak of lung injuries and deaths associated with e-cigarettes, or vaping, continues to spread across the U.S., researchers at Intermountain Healthcare in Salt Lake City have effectively developed a best practice treatment guide to quickly identify and treat…
Physicians create guide for identifying, treating vaping lung illness
Clinicians’ tool for EVALI treatment published in The Lancet Respiratory Medicine
Researchers report new insights into Parkinson’s disease-related mortality
A Dutch study published in the Journal of Parkinson’s Disease identifies risk factors associated with increased mortality in patients with PD compared to the general population
Supplements don’t preserve kidney health in Type 2 diabetes
Vitamin D and fish oil don’t prevent loss of kidney function in adults with type 2 diabetes, a clinical study shows.
New technique to identify a common cause to TMA diseases for which there is a treatment
Researchers develop a new technique to identify a cause that is common to diseases related to thrombotic microangiopathies (TMA) for which there is a treatment that could be used more widely