A new study by researchers at the UNC School of Medicine has identified a new biological function of 2’3’-cGAMP in the control of cell migration and cancer metastasis. This research also provides further insights into statin drugs that block cell migration.
Tag: Innate Immune Response
Study Explores Sex Differences in the Effects of SARS-CoV-2 in Young Adults
Suggests a more proactive, innate immune response among females
MD Anderson Research Highlights for July 13, 2022
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include new targets involved in protecting DNA replication forks and preventing inflammatory responses, a new treatment option for elderly patients with late-stage acute myeloid leukemia, insights into the breast cancer tumor microenvironment, biomarkers of response to targeted and immune therapies, a novel cellular therapy option for osteosarcoma and a new target for inducing ferroptosis in cancer cells.
New pathogenic mechanism for influenza NS1 protein found
Researchers report the biological effects of influenza protein NS1 binding to RIG-I — the binding directly quiets the alarm that activates the cellular innate immunity defense against the infection. This is a newly described way for flu to antagonize the host cellular antiviral response.