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UrduScientists have discovered a mechanism by which an area of a protein shape-shifts to convert vitamin A into a form usable by the eye’s light-sensing photoreceptor cells.
Tag: Endoplasmic Reticulum
Research Group Identifies Potential Therapeutic Target for Lupus
Inhibiting IRE1α, a molecule activated by the endoplasmic reticulum in neutrophils, counters disease progression in lupus mice.
Vinyl Chloride, Nerve Growth Factor, Chemical Warfare, and More Examined in March 2020 Toxicological Sciences
The March 2020 issue of Toxicological Sciences features leading research in toxicology, covering investigations in biotransformation, toxicokinetics, and pharmacokinetics in addition to work in exposure sciences and environmental toxicology.
Study Reveals New Way to Treat Stroke Using an Already FDA-Approved Drug
Granulocyte colony-stimulating factor (GCSF) is currently used to treat neutropenia due to chemotherapy and has been successfully used for patients who require bone marrow transplants. The study is the first to report on the neuroprotective effect of GCSF in vivo and showed that it improved neurological deficits that occur in the first few days following cerebral ischemia. GCSF improved long-term behavioral outcomes while also stimulating a neural progenitor recovery response in a mouse model.