Vinyl Chloride, Nerve Growth Factor, Chemical Warfare, and More Examined in March 2020 Toxicological Sciences

The March 2020 edition of Toxicological Sciences, the Society of Toxicology’s official journal, highlights leading research in toxicology as well as including new features designed to advance the journal. Volume 174, Issue 1, covers investigations in biotransformation, toxicokinetics, and pharmacokinetics in addition to work in exposure sciences and environmental toxicology.

A new article category introduced last month, ToxPoint, sees its second installment in the March 2020 issue of ToxSci. ToxPoint articles are designed to catalyze discussions around a cutting-edge toxicological topic. The March feature is entitled, “Dissecting Functional RNA Modifications in Responses to Environmental Exposure—Mechanistic Toxicology Research Enters a New Era.” 

In addition, the four Tox Spotlight articles in the March 2020 issue represent the diversity within the toxicology field, featuring research on biomarkers, environmental toxicology, and neurotoxicology:

• “Urinary TCP1-eta: A Cortical Damage Marker for the Pathophysiological Diagnosis and Prognosis of Acute Kidney Injury”
• “Hepatic Injury Caused by the Environmental Toxicant Vinyl Chloride Is Sex-Dependent in Mice”
• “A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin”
• “Nerve Growth Factor Protects against Pyrethroid-Induced Endoplasmic Reticulum (ER) Stress in Primary Hippocampal Neurons”

Also published in Volume 174, Issue 1, are manuscripts on computational toxicology and databases; emerging technologies, methods, and models; and molecular, biochemical, and systems toxicology.

The mission of Toxicological Sciences is to publish a broad spectrum of impactful research in the field of toxicology. ToxSci: Your science. Your journal.

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