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Tag: Breast Cancer
Overweight and obesity linked to higher cancer risks in large Danish study
Overweight and obesity were associated with higher risks of several common cancers in a 40-year, nationwide Danish study. In the Journal of Internal Medicine study, there were 20,706 cancers among 313,321 adults diagnosed with overweight and obesity compared with 18,480…
Cancer mortality continues steady decline, driven by progress against lung cancer
Drop of 2.2% from 2016 to 2017 is largest ever reported
Despite effective therapy, US rate of breast conservation lower than other countries
Women in North America more likely to undergo mastectomy in one or both breasts relative to comparable women treated in Europe or Asia
Overweight and obesity linked to higher cancer risks in large Danish study
Overweight and obesity were associated with higher risks of several common cancers in a 40-year, nationwide Danish study. In the Journal of Internal Medicine study, there were 20,706 cancers among 313,321 adults diagnosed with overweight and obesity compared with 18,480…
Cancer mortality continues steady decline, driven by progress against lung cancer
Drop of 2.2% from 2016 to 2017 is largest ever reported
Two projects receive NIH grant for breast cancer research
UC Riverside research is supported by a four-year grant worth more than $1.2 million
Despite effective therapy, US rate of breast conservation lower than other countries
Women in North America more likely to undergo mastectomy in one or both breasts relative to comparable women treated in Europe or Asia
Two projects receive NIH grant for breast cancer research
UC Riverside research is supported by a four-year grant worth more than $1.2 million
Can the flu shot help fight cancer?
Researchers at Rush University Medical Center find that injecting influenza vaccines into tumors triggers immune system response
Genetic study provides most comprehensive map of risk to date of breast cancer risk
A major international study of the genetics of breast cancer has identified more than 350 DNA ‘errors’ that increase an individual’s risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes. The…
New compounds block master regulator of cancer growth, metastasis
CHAMPAIGN, Ill. — Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and in mouse models…
Start of phase II clinical trial in four types of terminal cancers
December 15, 2019 N. N. The Alexandrov National Cancer Centre begins phase II case-control clinical trial of its immuno-oncology agent, Elenagen. Inoperable late-stage cancer patients with triple-negative breast cancer, ovarian cancer, stomach cancer or prostate cancer will be randomized and…
Can the flu shot help fight cancer?
Researchers at Rush University Medical Center find that injecting influenza vaccines into tumors triggers immune system response
Genetic study provides most comprehensive map of risk to date of breast cancer risk
A major international study of the genetics of breast cancer has identified more than 350 DNA ‘errors’ that increase an individual’s risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes. The…
New compounds block master regulator of cancer growth, metastasis
CHAMPAIGN, Ill. — Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and in mouse models…
Start of phase II clinical trial in four types of terminal cancers
December 15, 2019 N. N. The Alexandrov National Cancer Centre begins phase II case-control clinical trial of its immuno-oncology agent, Elenagen. Inoperable late-stage cancer patients with triple-negative breast cancer, ovarian cancer, stomach cancer or prostate cancer will be randomized and…
Can the flu shot help fight cancer?
Physicians and scientists at Rush University Medical Center have found that injecting tumors with influenza vaccines, including some FDA-approved seasonal flu shots, turns cold tumors to hot, a discovery that could lead to an immunotherapy to treat cancer. The study results were published December 30th in the Proceedings of the National Academy of Sciences.
Combining neurologic and blood pressure drugs reduces breast tumor development in mice
WASHINGTON — Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat…
Report links recommended physical activity levels to lower risk of seven cancers
More activity linked to lower risk for several cancer types
Scientists learn what women know — and don’t know — about breast density and cancer risk
Breast density is a risk factor for cancer, but no study has asked women what they know about breast density in relation to screening. A new three-state-wide study out of Dartmouth’s Norris Cotton Cancer Center reveals varying knowledge on the topic
Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer
Anthracyclines remain a cornerstone of breast cancer therapy in combination with new-generation targeted drugs such as trastuzumab. Both types of drugs are major culprits in chemotherapy-induced heart disease. A recent study showed that being overweight or obese was a risk…
Fibroblasts involved in healing spur tumor growth in cancer
Vital to healing wounds, fibroblasts have a ‘misguided’ response to cancer cells, according to Tel Aviv University researchers
A new role for a triple-negative breast cancer target
The protein, known to be implicated in an aggressive form of cancer, is also critical for normal mammary gland development during puberty, according to research in mice led by the University of Pennsylvania’s Rumela Chakrabarti
Penn researchers predict 10-year breast cancer recurrence with MRI scans
Using imaging to characterize the genetic makeup of tumors paves the way for individualized, non-invasive treatment
Fibroblasts involved in healing spur tumor growth in cancer
Vital to healing wounds, fibroblasts have a ‘misguided’ response to cancer cells, according to Tel Aviv University researchers
A new role for a triple-negative breast cancer target
The protein, known to be implicated in an aggressive form of cancer, is also critical for normal mammary gland development during puberty, according to research in mice led by the University of Pennsylvania’s Rumela Chakrabarti
Penn researchers predict 10-year breast cancer recurrence with MRI scans
Using imaging to characterize the genetic makeup of tumors paves the way for individualized, non-invasive treatment
Bonni Lee Guerin, MD Honored By American Cancer Society – Northeast Region
Bonni Lee Guerin, MD, hematologist/oncologist and physician researcher at Overlook Medical Center, was honored by the American Cancer Society for her role in advancing breast cancer treatment and prevention. In addition to her forward-looking clinical approach, Dr. Guerin is the principal investigator (PI) of numerous clinical trials exploring new ways to incorporate the latest advances in the management of breast cancer. Dr. Guerin was PI at Atlantic Health System, with the largest number of study participants of any center in the New York-New Jersey metro area, for the landmark TAILORx clinical trial.
Cancer therapy may be aided by induced macropinocytosis, a rare form of cell death
In preclinical experiments, a metabolic inhibitor killed a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues
National clinical trial provides mastectomy alternative for recurrent breast cancer
Mastectomy has historically been the standard treatment for breast cancer patients experiencing recurrence after an initial lumpectomy and whole-breast radiation. Now, a phase 2 clinical trial led by Douglas W. Arthur, M.D., chair and professor in the Department of Radiation…
Cancer therapy may be aided by induced macropinocytosis, a rare form of cell death
In preclinical experiments, a metabolic inhibitor killed a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues
National clinical trial provides mastectomy alternative for recurrent breast cancer
Mastectomy has historically been the standard treatment for breast cancer patients experiencing recurrence after an initial lumpectomy and whole-breast radiation. Now, a phase 2 clinical trial led by Douglas W. Arthur, M.D., chair and professor in the Department of Radiation…
Large study links sustained weight loss to reduced breast cancer risk
Results show that higher breast cancer risk from excess body weight can be reversed with weight loss
Dense breast notifications are having little impact
FDA should address potential unintended consequences of the notifications before implementing them
Novel genetic signature that can predict some kinds of breast cancer is identified
The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, as a model of angiogenesis, with analysis of transcriptomic gene expression profiles from public breast cancer databases.
Large study links sustained weight loss to reduced breast cancer risk
Results show that higher breast cancer risk from excess body weight can be reversed with weight loss
AI improves breast cancer risk prediction
OAK BROOK, Ill. – A sophisticated type of artificial intelligence (AI) can outperform existing models at predicting which women are at future risk of breast cancer, according to a study published in the journal Radiology . Most existing breast cancer…
Dense breast notifications are having little impact
FDA should address potential unintended consequences of the notifications before implementing them
Novel genetic signature that can predict some kinds of breast cancer is identified
The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, as a model of angiogenesis, with analysis of transcriptomic gene expression profiles from public breast cancer databases.
AI improves breast cancer risk prediction
OAK BROOK, Ill. – A sophisticated type of artificial intelligence (AI) can outperform existing models at predicting which women are at future risk of breast cancer, according to a study published in the journal Radiology . Most existing breast cancer…
Study examines causes of death in US breast cancer survivors
Survival rates for patients with breast cancer have improved significantly in the last four decades, and many patients will eventually die from non-cancer-related causes. Researchers recently conducted the largest population-based long-term retrospective analysis of non-cancer causes of death among patients…
Study examines causes of death in US breast cancer survivors
Survival rates for patients with breast cancer have improved significantly in the last four decades, and many patients will eventually die from non-cancer-related causes. Researchers recently conducted the largest population-based long-term retrospective analysis of non-cancer causes of death among patients…
Mayo Clinic researchers present findings at the 2019 San Antonio Breast Cancer Symposium
Mayo Clinic researchers will present findings at the San Antonio Breast Cancer Symposium Dec. 10–14 in San Antonio.
Study on Negative Perception of Support Groups Garners Research Paper Award
A study on the negative perception of support groups among older breast cancer survivors was selected as a 2019 Best Original Research Paper in the journal Cancer Nursing.
Breast biopsies after neoadjuvant chemotherapy accurately predict presence of residual breast cancer
Researchers from The University of Texas MD Anderson Cancer Center have identified a standardized protocol that uses image-guided breast biopsies to reliably predict residual disease in breast cancer patients and that potentially identifies exceptional responders who may not require surgery.
Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival
Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden (RCB) continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes.
Breast cancer patients with government insurance at higher risk of death
Medicare and Medicaid patients with breast cancer also had an increased likelihood of stopping their clinical trial treatment early, same study found
IU School of Medicine team learns how to predict triple negative breast cancer recurrence
Discovery marks progress in IU Precision Health Initiative Grand Challenge
Breast-conserving treatment without surgery not supported at this time
Results of NRG Oncology study BR005